PMID- 28370456
OWN - NLM
STAT- MEDLINE
DCOM- 20190920
LR  - 20221207
IS  - 1520-6777 (Electronic)
IS  - 0733-2467 (Linking)
VI  - 37
IP  - 1
DP  - 2018 Jan
TI  - Predictors for detrusor overactivity following extensive vaginal pelvic 
      reconstructive surgery.
PG  - 192-199
LID - 10.1002/nau.23273 [doi]
AB  - AIM: This study aims to identify the predictors for detrusor overactivity (DO) in 
      women following extensive vaginal pelvic reconstructive surgery (PRS) for 
      advanced pelvic organ prolapse (POP). METHODS: We enrolled 1503 women who had 
      prolapse POP-Q stage >/= 3 and underwent vaginal PRS with or without MUS from 
      January 2006 to December 2015. All subjects completed a 72-h voiding diary, 
      IIQ-7, UDI-6, POPDI-6, and PISQ-12. Urodynamics (UDS) was performed pre- and 
      post-operatively. RESULTS: Among 1503 women, 56 patients were excluded due to 
      incomplete data. Women who had trans-vaginal mesh were 1083 of 1447 (74.8%) and 
      concomitant MUS were 353 (24.4%). Pre-operative DO were 245 (16.9%) and 24.5% 
      (60/245) of them continued to have persistent DO post-operatively. Women who had 
      normal pre-operative stable detrusor were 1202 (83.1%) and 3.5% (30/1202) 
      developed de novo DO post-operatively. The overall incidence of post-operative DO 
      was 6.2% (90/1447). Patients with age >/=66 year, neurological factors like 
      Cerebrovascular accident and Parkinsonian disease, pre-operative bladder outlet 
      obstruction (BOO) maximum urethral closure pressure (MUCP) >/=60 cmH(2) O, Maximum 
      flow rate (MFR) <15 mL/s and detrusor at maximum flow (Dmax) >/=20 cmH(2) O) and 
      post-void residue (PVR) >/=200 mL hold a significant higher risk of developing DO 
      either persistent or de novo following PRS. CONCLUSION: Age >/=66 year, 
      neurological factors like CVA and Parkinsonian disease, pre-operative MUCP 
      >/=60 cmH(2) O, MFR < 15 mL, Dmax >/= 20 cmH(2) O, and PVR >/= 200 mL are independent 
      risk factors for developing post-operative DO following vaginal PRS for advanced 
      POP.
CI  - (c) 2017 Wiley Periodicals, Inc.
FAU - Lo, Tsia-Shu
AU  - Lo TS
AUID- ORCID: 0000-0002-3885-1359
AD  - Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Keelung 
      Medical Center, Keelung, Taiwan, People's Republic of China.
AD  - Division of Urogynecology, Department of Obstetrics and Gynecology, Linkou, Chang 
      Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, People's Republic 
      of China.
AD  - Department of Obstetrics and Gynaecology, Chang Gung Memorial Hospital, Xiamen 
      Medical Center, Xiamen, People's Republic of China.
AD  - Chang Gung University, School of Medicine, Taoyuan, Taiwan, People's Republic of 
      China.
FAU - Nagashu, Shailaja
AU  - Nagashu S
AD  - Department of Obstetrics and Gynaecology, Peoples Education Society Medical 
      College and Research Centre, Kuppam, Andhra Pradesh, India.
AD  - Fellow, Division of Urogynaecology, Department of Obstetrics and Gynaecology, 
      Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, People's 
      Republic of China.
FAU - Hsieh, Wu-Chiao
AU  - Hsieh WC
AD  - Division of Urogynecology, Department of Obstetrics and Gynecology, Linkou, Chang 
      Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, People's Republic 
      of China.
FAU - Uy-Patrimonio, Ma Clarissa
AU  - Uy-Patrimonio MC
AD  - Fellow, Division of Urogynaecology, Department of Obstetrics and Gynaecology, 
      Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, People's 
      Republic of China.
AD  - Department of Obstetrics and Gynecology, Dr. Pablo O. Torre Memorial Hospital, 
      Bacolod City, Philippines.
FAU - Yi-Hao, Lin
AU  - Yi-Hao L
AD  - Division of Urogynecology, Department of Obstetrics and Gynecology, Linkou, Chang 
      Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, People's Republic 
      of China.
LA  - eng
PT  - Journal Article
DEP - 20170331
PL  - United States
TA  - Neurourol Urodyn
JT  - Neurourology and urodynamics
JID - 8303326
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Factors
MH  - Aged
MH  - Female
MH  - Gynecologic Surgical Procedures/*adverse effects
MH  - Humans
MH  - Middle Aged
MH  - Pelvic Floor/surgery
MH  - Postoperative Complications/*diagnosis
MH  - Predictive Value of Tests
MH  - Preexisting Condition Coverage
MH  - Plastic Surgery Procedures/*adverse effects
MH  - Risk Factors
MH  - Urinary Bladder, Overactive/*diagnosis/epidemiology/etiology
MH  - Urodynamics
MH  - Young Adult
OTO - NOTNLM
OT  - bladder outlet obstruction
OT  - detrusor at maximum flow
OT  - detrusor overactivity
OT  - overactive bladder (OAB)
OT  - post-void residue (PVR)
EDAT- 2017/04/04 06:00
MHDA- 2019/09/21 06:00
CRDT- 2017/04/04 06:00
PHST- 2016/09/03 00:00 [received]
PHST- 2016/12/26 00:00 [accepted]
PHST- 2017/04/04 06:00 [pubmed]
PHST- 2019/09/21 06:00 [medline]
PHST- 2017/04/04 06:00 [entrez]
AID - 10.1002/nau.23273 [doi]
PST - ppublish
SO  - Neurourol Urodyn. 2018 Jan;37(1):192-199. doi: 10.1002/nau.23273. Epub 2017 Mar 
      31.