PMID- 28372473
OWN - NLM
STAT- MEDLINE
DCOM- 20170605
LR  - 20181113
IS  - 1744-5116 (Electronic)
IS  - 1388-0209 (Print)
IS  - 1388-0209 (Linking)
VI  - 55
IP  - 1
DP  - 2017 Dec
TI  - Selection of chemical markers for the quality control of medicinal plants of the 
      genus Cecropia.
PG  - 1500-1512
LID - 10.1080/13880209.2017.1307421 [doi]
AB  - CONTEXT: Several Cecropia (Cecropiaceae) species are traditionally used in Latin 
      America for the treatment of a variety of diseases including diabetes, arterial 
      hypertension, asthma, bronchitis, anxiety, and inflammation. At present, a number 
      of commercial products based on these plants have been introduced into the market 
      with very little information on methods for guaranteeing their quality and 
      safety. OBJECTIVE: This work proposes potential chemical markers for the quality 
      control of the raw materials of Cecropia obtusifolia Bertol., Cecropia peltata 
      L., Cecropia glaziovii Snethl., Cecropia pachystachya Trecul, and Cecropia 
      hololeuca Miq. METHODS: The Herbal Chemical Marker Ranking System (Herb MaRS) 
      developed by the National Institute of Complementary Medicine (NICM) at the 
      University of Western Sydney was used for selecting chemical markers for the 
      quality control of selected medicinal species of Cecropia. This review covers the 
      period from 1982 to 2016. RESULTS: Chlorogenic acid, flavonoidal glycosides 
      (orientin, isoorientin, vitexin, isovitexin, and rutin), catechin, epicatechin, 
      procyanidins (B2, B5, and C1), steroids (beta-sitosterol), and triterpenoids 
      (alpha-amyrin, pomolic, tormentic and ursolic acids) were selected as chemical 
      markers for the quality control of the leaves. CONCLUSION: It is necessary to 
      establish comprehensive standards for guaranteeing quality, safety and efficacy 
      of herbal drugs. The selection of adequate chemical markers for quality control 
      purposes requires a good knowledge about the chemical composition of medicinal 
      plants and their associated biological properties. To the best of our knowledge 
      this review article is the first to address the identification and quantitative 
      determination of the chemical markers for the genus Cecropia.
FAU - Rivera-Mondragon, Andres
AU  - Rivera-Mondragon A
AD  - a Natural Products & Food Research and Analysis (NatuRA), Department of 
      Pharmaceutical Sciences , University of Antwerp , Antwerp , Belgium.
FAU - Ortiz, Orlando O
AU  - Ortiz OO
AD  - b Herbarium PMA , Universidad de Panama, Estafeta Universitaria , Panama City , 
      Republic of Panama.
FAU - Bijttebier, Sebastiaan
AU  - Bijttebier S
AD  - a Natural Products & Food Research and Analysis (NatuRA), Department of 
      Pharmaceutical Sciences , University of Antwerp , Antwerp , Belgium.
FAU - Vlietinck, Arnold
AU  - Vlietinck A
AD  - a Natural Products & Food Research and Analysis (NatuRA), Department of 
      Pharmaceutical Sciences , University of Antwerp , Antwerp , Belgium.
FAU - Apers, Sandra
AU  - Apers S
AD  - a Natural Products & Food Research and Analysis (NatuRA), Department of 
      Pharmaceutical Sciences , University of Antwerp , Antwerp , Belgium.
FAU - Pieters, Luc
AU  - Pieters L
AD  - a Natural Products & Food Research and Analysis (NatuRA), Department of 
      Pharmaceutical Sciences , University of Antwerp , Antwerp , Belgium.
FAU - Caballero-George, Catherina
AU  - Caballero-George C
AD  - c Group of Pharmaceutical Research , Institute of Scientific Research and High 
      Technology Services (INDICASAT-AIP) , Panama , Republic of Panama.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Pharm Biol
JT  - Pharmaceutical biology
JID - 9812552
RN  - 0 (Phytochemicals)
RN  - 0 (Plant Extracts)
SB  - IM
MH  - Animals
MH  - Cecropia Plant/*chemistry/classification
MH  - Humans
MH  - Phytochemicals/isolation & purification/*standards/therapeutic use
MH  - Phytotherapy
MH  - Plant Extracts/isolation & purification/*standards/therapeutic use
MH  - Plants, Medicinal
MH  - *Quality Control
PMC - PMC6130728
OTO - NOTNLM
OT  - Urticaceae
OT  - herbal medicine
OT  - quality control
EDAT- 2017/04/05 06:00
MHDA- 2017/06/06 06:00
PMCR- 2017/04/04
CRDT- 2017/04/05 06:00
PHST- 2017/04/05 06:00 [entrez]
PHST- 2017/04/05 06:00 [pubmed]
PHST- 2017/06/06 06:00 [medline]
PHST- 2017/04/04 00:00 [pmc-release]
AID - 1307421 [pii]
AID - 10.1080/13880209.2017.1307421 [doi]
PST - ppublish
SO  - Pharm Biol. 2017 Dec;55(1):1500-1512. doi: 10.1080/13880209.2017.1307421.