PMID- 28372711
OWN - NLM
STAT- MEDLINE
DCOM- 20170424
LR  - 20181113
IS  - 1557-9859 (Electronic)
IS  - 0025-7125 (Print)
IS  - 0025-7125 (Linking)
VI  - 101
IP  - 3
DP  - 2017 May
TI  - Outpatient Emergencies: Anaphylaxis.
PG  - 521-536
LID - S0025-7125(16)37396-5 [pii]
LID - 10.1016/j.mcna.2016.12.003 [doi]
AB  - Anaphylactic fatalities are rare; however, mild reactions can rapidly progress to 
      cardiovascular and respiratory arrest. The clinical course of anaphylaxis can be 
      unpredictable. Prompt and early use of epinephrine should be considered. Most 
      anaphylaxis episodes have an immunologic mechanism involving immunoglobulin E 
      (IgE). Foods are the most common cause in children; medications and insect stings 
      are more common in adults. When the cause is not completely avoidable or cannot 
      be determined, a patient should be supplied with autoinjectable epinephrine and 
      be instructed its use. They should keep the device with them at all times and 
      taught the signs and symptoms of anaphylaxis.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Commins, Scott P
AU  - Commins SP
AD  - Division of Rheumatology, Allergy and Immunology, Department of Medicine, 
      Thurston Research Center, University of North Carolina, 3300 Thurston Building, 
      CB 7280, Chapel Hill, NC 27599-7280, USA; Division of Rheumatology, Allergy and 
      Immunology, Department of Pediatrics, Thurston Research Center, University of 
      North Carolina, 3300 Thurston Building, CB 7280, Chapel Hill, NC 27599-7280, USA. 
      Electronic address: scommins@email.unc.edu.
LA  - eng
GR  - K08 AI085190/AI/NIAID NIH HHS/United States
GR  - R56 AI113095/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Review
DEP - 20170302
PL  - United States
TA  - Med Clin North Am
JT  - The Medical clinics of North America
JID - 2985236R
RN  - 0 (Adrenergic beta-Agonists)
RN  - 0 (Glucocorticoids)
RN  - 0 (Histamine Antagonists)
RN  - 37341-29-0 (Immunoglobulin E)
RN  - YKH834O4BH (Epinephrine)
SB  - IM
MH  - Adrenergic beta-Agonists/therapeutic use
MH  - Airway Management/methods
MH  - Anaphylaxis/*diagnosis/*drug therapy/physiopathology
MH  - Cardiopulmonary Resuscitation
MH  - *Emergencies
MH  - Epinephrine/therapeutic use
MH  - Glucocorticoids/therapeutic use
MH  - Hemodynamics
MH  - Histamine Antagonists/therapeutic use
MH  - Humans
MH  - Immunoglobulin E/immunology
MH  - *Outpatients
MH  - Severity of Illness Index
PMC - PMC5381731
MID - NIHMS840301
OTO - NOTNLM
OT  - Allergy
OT  - Anaphylaxis
OT  - IgE
OT  - Mast cell
OT  - Tryptase
EDAT- 2017/04/05 06:00
MHDA- 2017/04/25 06:00
PMCR- 2018/05/01
CRDT- 2017/04/05 06:00
PHST- 2017/04/05 06:00 [entrez]
PHST- 2017/04/05 06:00 [pubmed]
PHST- 2017/04/25 06:00 [medline]
PHST- 2018/05/01 00:00 [pmc-release]
AID - S0025-7125(16)37396-5 [pii]
AID - 10.1016/j.mcna.2016.12.003 [doi]
PST - ppublish
SO  - Med Clin North Am. 2017 May;101(3):521-536. doi: 10.1016/j.mcna.2016.12.003. Epub 
      2017 Mar 2.