PMID- 28372946 OWN - NLM STAT- MEDLINE DCOM- 20170710 LR - 20180702 IS - 1873-1740 (Electronic) IS - 0033-0620 (Linking) VI - 59 IP - 6 DP - 2017 May-Jun TI - The Role of Embolic Protection in Carotid Stenting Progress in Cardiovascular Diseases (PCVD). PG - 612-618 LID - S0033-0620(17)30050-6 [pii] LID - 10.1016/j.pcad.2017.03.003 [doi] AB - Embolic protection device (EPD) use has become ubiquitous and is currently mandated by the Centers for Medicare and Medicaid (CMS) for reimbursement in conjunction with carotid artery stenting (CAS). There are two classes of EPD devices: distal filter EPD (f-EPD) and proximal EPD (p-EPD). Measuring the incremental benefit of one strategy over the other remains problematic for several reasons. The first lies in the difficulty of defining an embolic event as transcranial Doppler and diffusion-weighted magnetic resonance imaging abnormalities may not correlate with clinical events. Next, f-EPD is used more frequently than p-EPD making direct comparisons challenging, as analyses to this point have been underpowered. However, there are several promising emerging techniques and technologies that warrant further investigation. CI - Copyright (c) 2017 Elsevier Inc. All rights reserved. FAU - Kobayashi, Taisei AU - Kobayashi T AD - Cardiovascular Division, University of Pennsylvania; Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, University of Pennsylvania. FAU - Giri, Jay AU - Giri J AD - Cardiovascular Division, University of Pennsylvania; Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, University of Pennsylvania. Electronic address: Jay.Giri@uphs.upenn.edu. LA - eng PT - Journal Article PT - Review DEP - 20170331 PL - United States TA - Prog Cardiovasc Dis JT - Progress in cardiovascular diseases JID - 0376442 SB - IM MH - Angioplasty/adverse effects/*instrumentation MH - Carotid Artery Diseases/complications/diagnostic imaging/*therapy MH - Diffusion Magnetic Resonance Imaging MH - *Embolic Protection Devices MH - Humans MH - Intracranial Embolism/diagnostic imaging/etiology/prevention & control MH - Predictive Value of Tests MH - Risk Assessment MH - Risk Factors MH - *Stents MH - Treatment Outcome MH - Ultrasonography, Doppler, Transcranial OTO - NOTNLM OT - Carotid artery stenting OT - Embolic protection devices OT - Stroke EDAT- 2017/04/05 06:00 MHDA- 2017/07/14 06:00 CRDT- 2017/04/05 06:00 PHST- 2017/03/28 00:00 [received] PHST- 2017/03/28 00:00 [accepted] PHST- 2017/04/05 06:00 [pubmed] PHST- 2017/07/14 06:00 [medline] PHST- 2017/04/05 06:00 [entrez] AID - S0033-0620(17)30050-6 [pii] AID - 10.1016/j.pcad.2017.03.003 [doi] PST - ppublish SO - Prog Cardiovasc Dis. 2017 May-Jun;59(6):612-618. doi: 10.1016/j.pcad.2017.03.003. Epub 2017 Mar 31.