PMID- 28374203
OWN - NLM
STAT- MEDLINE
DCOM- 20190114
LR  - 20190114
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 25
IP  - 31
DP  - 2018 Nov
TI  - Association between exposure to pesticides and disorder on hematological 
      parameters and kidney function in male agricultural workers.
PG  - 30802-30807
LID - 10.1007/s11356-017-8958-9 [doi]
AB  - Pesticides occupy a critical position among many chemicals to which man can be 
      exposed; their diffusion into the environment causes killing and damaging of some 
      forms of life. The lack of highly selective pesticide action represents risk both 
      for man and other desirable forms of life present in the environment. The present 
      study was designed to evaluate the relation between exposure to pesticides and 
      disorder on hematological parameters and kidney function of male agricultural 
      workers with the mean age 37.11 +/- 9.3. Another 100 unexposed men matched for age, 
      and socioeconomic status were recruited as a control to compare the levels of 
      hemoglobin, hematocrit, red blood cells (RBCs), mean corpuscular volume (MCV), 
      mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration 
      (MCHC), and urea and creatinine concentration. The results indicate that there 
      was no significant difference in hemoglobin concentration and hematocrit value 
      among exposed group as compared to control group. However, there was a 
      significant decrease (P < 0.05) in the RBCs count and a highly significant 
      increase (P < 0.01) in MCV among exposed group. There was no significant 
      difference in MCH and MCHC among exposed group. There was a significant increase 
      (P < 0.05) in urea (39.4 +/- 22 mg/dl) among exposed group as compared to control 
      (35.7 +/- 26.3 mg/dl). Also, there was a highly significant increase (P < 0.01) in 
      creatinine among exposed group (0.953 +/- 0.3 mg/dl) as compared to control 
      (0.8 +/- 0.2 mg/dl). In conclusion, exposure to pesticides produces a variety of 
      hematological parameter disorders as well as kidney malfunction in human.
FAU - Hassanin, Nagah M
AU  - Hassanin NM
AD  - City of Scientific Research and Technology Applications (SRTA-City), New Borg El 
      Arab City, Alexandria, 21934, Egypt.
FAU - Awad, Osama M
AU  - Awad OM
AD  - High Institute of Public Health, University of Alexandria, Alexandria, Egypt.
FAU - El-Fiki, Sourya
AU  - El-Fiki S
AD  - High Institute of Public Health, University of Alexandria, Alexandria, Egypt.
FAU - Abou-Shanab, Reda A I
AU  - Abou-Shanab RAI
AD  - City of Scientific Research and Technology Applications (SRTA-City), New Borg El 
      Arab City, Alexandria, 21934, Egypt. redaabushanab@yahoo.com.
FAU - Abou-Shanab, Ahmed R A
AU  - Abou-Shanab ARA
AD  - Faculty of Medicine, Alexandria University, Alexandria, Egypt.
FAU - Amer, Ranya A
AU  - Amer RA
AD  - City of Scientific Research and Technology Applications (SRTA-City), New Borg El 
      Arab City, Alexandria, 21934, Egypt.
LA  - eng
PT  - Journal Article
DEP - 20170403
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Pesticides)
SB  - IM
MH  - Adult
MH  - Agriculture/*statistics & numerical data
MH  - Farmers/*statistics & numerical data
MH  - Hematologic Tests
MH  - Humans
MH  - Kidney/*drug effects
MH  - Kidney Function Tests
MH  - Male
MH  - Middle Aged
MH  - Occupational Exposure/*adverse effects
MH  - Pesticides/*toxicity
OTO - NOTNLM
OT  - Agriculture
OT  - Farmer
OT  - Hematological indices
OT  - Kidney
OT  - Pesticides exposure
EDAT- 2017/04/05 06:00
MHDA- 2019/01/15 06:00
CRDT- 2017/04/05 06:00
PHST- 2016/10/11 00:00 [received]
PHST- 2017/03/29 00:00 [accepted]
PHST- 2017/04/05 06:00 [pubmed]
PHST- 2019/01/15 06:00 [medline]
PHST- 2017/04/05 06:00 [entrez]
AID - 10.1007/s11356-017-8958-9 [pii]
AID - 10.1007/s11356-017-8958-9 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2018 Nov;25(31):30802-30807. doi: 
      10.1007/s11356-017-8958-9. Epub 2017 Apr 3.