PMID- 28378152
OWN - NLM
STAT- MEDLINE
DCOM- 20180315
LR  - 20181113
IS  - 2193-6226 (Electronic)
IS  - 2193-6218 (Linking)
VI  - 112
IP  - 3
DP  - 2017 Apr
TI  - [Development of antimicrobial resistance in Germany : What is the current 
      situation?].
PG  - 186-191
LID - 10.1007/s00063-017-0272-2 [doi]
AB  - BACKGROUND: The frequency of multidrug-resistant organisms (MDRO) is increasing 
      in Germany and worldwide. OBJECTIVES: Presentation of MDRO resistance rates and 
      prevalence in Germany MATERIALS AND METHODS: Results from the Antibiotic 
      Resistance Surveillance (ARS) and Hospital Infection Surveillance Systems 
      (Krankenhausinfektions-Surveillance-Systems, KISS) and from recent prevalence 
      surveys are presented. RESULTS: MRSA-resistance rates and the prevalence of 
      methicillin-resistant Staphylococcus aureus (MRSA) have remained at a stable 
      level over the last few years. In contrast, vancomycin-resistant enterococci 
      (VRE) and multidrug-resistant gramnegative (MRGN) bacteria have increased 
      considerably. VRE prevalence has more than tripled in the past 5 years, and 
      Escherichia coli resistant to third-generation cephalosporins, 
      acylureidopenicillins, and fluoroquinolones increased by 43% in 2015 compared 
      with the previous year. CONCLUSIONS: New policies to control MDRO should focus on 
      VRE and the heterogeneous group of MRGN bacteria. In the case of the latter, the 
      different bacterial species' characteristics should be taken into consideration.
FAU - Maechler, F
AU  - Maechler F
AD  - Institut fur Hygiene und Umweltmedizin, Nationales Referenzzentrum fur die 
      Surveillance von Nosokomialen Infektionen, Charite Universitatsmedizin Berlin, 
      Hindenburgdamm 27, 12203, Berlin, Deutschland. friederike.maechler@charite.de.
FAU - Geffers, C
AU  - Geffers C
AD  - Institut fur Hygiene und Umweltmedizin, Nationales Referenzzentrum fur die 
      Surveillance von Nosokomialen Infektionen, Charite Universitatsmedizin Berlin, 
      Hindenburgdamm 27, 12203, Berlin, Deutschland.
FAU - Schwab, F
AU  - Schwab F
AD  - Institut fur Hygiene und Umweltmedizin, Nationales Referenzzentrum fur die 
      Surveillance von Nosokomialen Infektionen, Charite Universitatsmedizin Berlin, 
      Hindenburgdamm 27, 12203, Berlin, Deutschland.
FAU - Pena Diaz, L-A
AU  - Pena Diaz LA
AD  - Institut fur Hygiene und Umweltmedizin, Nationales Referenzzentrum fur die 
      Surveillance von Nosokomialen Infektionen, Charite Universitatsmedizin Berlin, 
      Hindenburgdamm 27, 12203, Berlin, Deutschland.
FAU - Behnke, M
AU  - Behnke M
AD  - Institut fur Hygiene und Umweltmedizin, Nationales Referenzzentrum fur die 
      Surveillance von Nosokomialen Infektionen, Charite Universitatsmedizin Berlin, 
      Hindenburgdamm 27, 12203, Berlin, Deutschland.
FAU - Gastmeier, P
AU  - Gastmeier P
AD  - Institut fur Hygiene und Umweltmedizin, Nationales Referenzzentrum fur die 
      Surveillance von Nosokomialen Infektionen, Charite Universitatsmedizin Berlin, 
      Hindenburgdamm 27, 12203, Berlin, Deutschland.
LA  - ger
PT  - Journal Article
PT  - Review
TT  - Entwicklung der Resistenzsituation in Deutschland : Wo stehen wir wirklich?
DEP - 20170404
PL  - Germany
TA  - Med Klin Intensivmed Notfmed
JT  - Medizinische Klinik, Intensivmedizin und Notfallmedizin
JID - 101575086
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Anti-Bacterial Agents/adverse effects/*therapeutic use
MH  - Bacterial Infections/*drug therapy/epidemiology
MH  - Cross Infection/*drug therapy/epidemiology
MH  - *Drug Resistance, Multiple, Bacterial
MH  - Escherichia coli Infections/drug therapy/epidemiology
MH  - Germany
MH  - Gram-Negative Bacterial Infections/drug therapy/epidemiology/microbiology
MH  - Humans
MH  - Intensive Care Units/statistics & numerical data
MH  - Methicillin-Resistant Staphylococcus aureus
MH  - Population Surveillance
MH  - Staphylococcal Infections/drug therapy
MH  - Vancomycin-Resistant Enterococci
OTO - NOTNLM
OT  - Infectious diseases
OT  - MRSA
OT  - Staphylococcus aureus
OT  - Surveillance
OT  - VRE
EDAT- 2017/04/06 06:00
MHDA- 2018/03/16 06:00
CRDT- 2017/04/06 06:00
PHST- 2017/01/04 00:00 [received]
PHST- 2017/02/13 00:00 [accepted]
PHST- 2017/04/06 06:00 [pubmed]
PHST- 2018/03/16 06:00 [medline]
PHST- 2017/04/06 06:00 [entrez]
AID - 10.1007/s00063-017-0272-2 [pii]
AID - 10.1007/s00063-017-0272-2 [doi]
PST - ppublish
SO  - Med Klin Intensivmed Notfmed. 2017 Apr;112(3):186-191. doi: 
      10.1007/s00063-017-0272-2. Epub 2017 Apr 4.