PMID- 28378564
OWN - NLM
STAT- MEDLINE
DCOM- 20170908
LR  - 20181113
IS  - 1598-6357 (Electronic)
IS  - 1011-8934 (Print)
IS  - 1011-8934 (Linking)
VI  - 32
IP  - 5
DP  - 2017 May
TI  - Factors Influencing the Gross Motor Outcome of Intensive Therapy in Children with 
      Cerebral Palsy and Developmental Delay.
PG  - 873-879
LID - 10.3346/jkms.2017.32.5.873 [doi]
AB  - The study was designed to identify factors influencing the short term effect of 
      intensive therapy on gross motor function in children with cerebral palsy or 
      developmental delay. Retrospectively, total Gross Motor Function Measure-88 
      (GMFM-88) scores measured during the first and last weeks of intensive therapy 
      were analyzed (n = 103). Good and poor responder groups were defined as those in 
      the top and bottom 25% in terms of score difference, respectively. The GMFM-88 
      score increased to 4.67 +/- 3.93 after 8 weeks of intensive therapy (P < 0.001). 
      Gross Motor Function Classification System (GMFCS) level (I-II vs. IV-V; odds 
      ratio [OR] = 7.763, 95% confidence interval [CI] = 2.177-27.682, P = 0.002) was a 
      significant factor in a good response to therapy. Age (>/= 36 months; OR = 2.737, 
      95% CI = 1.003-7.471, P = 0.049) and GMFCS level (I-II vs. IV-V; OR = 0.189, 95% 
      CI = 0.057-0.630, P = 0.007; and III vs. IV-V; OR = 0.095, 95% CI = 0.011-0.785, 
      P = 0.029) were significantly associated with a poor response. GMFCS level is the 
      most important prognostic factor for the effect of intensive therapy on gross 
      motor function. In addition, age >/= 36 months, is associated with a poor outcome.
CI  - (c) 2017 The Korean Academy of Medical Sciences.
FAU - Hong, Bo Young
AU  - Hong BY
AUID- ORCID: 0000-0001-9290-6173
AD  - Department of Rehabilitation Medicine, St. Vincent's Hospital, College of 
      Medicine, The Catholic University of Korea, Suwon, Korea. byhong@catholic.ac.kr.
FAU - Jo, Leechan
AU  - Jo L
AUID- ORCID: 0000-0001-7375-3626
AD  - Department of Rehabilitation Medicine, St. Vincent's Hospital, College of 
      Medicine, The Catholic University of Korea, Suwon, Korea.
FAU - Kim, Joon Sung
AU  - Kim JS
AUID- ORCID: 0000-0001-7457-593X
AD  - Department of Rehabilitation Medicine, St. Vincent's Hospital, College of 
      Medicine, The Catholic University of Korea, Suwon, Korea.
FAU - Lim, Seong Hoon
AU  - Lim SH
AUID- ORCID: 0000-0002-5475-4153
AD  - Department of Rehabilitation Medicine, St. Vincent's Hospital, College of 
      Medicine, The Catholic University of Korea, Suwon, Korea.
FAU - Bae, Jung Min
AU  - Bae JM
AUID- ORCID: 0000-0001-5975-8519
AD  - Department of Dermatology, St. Vincent's Hospital, College of Medicine, The 
      Catholic University of Korea, Suwon, Korea.
LA  - eng
PT  - Journal Article
PL  - Korea (South)
TA  - J Korean Med Sci
JT  - Journal of Korean medical science
JID - 8703518
SB  - IM
MH  - Cerebral Palsy/physiopathology/rehabilitation/*therapy
MH  - Child, Preschool
MH  - Developmental Disabilities/physiopathology/rehabilitation/*therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Motor Activity
MH  - Multivariate Analysis
MH  - Odds Ratio
MH  - Prognosis
MH  - Severity of Illness Index
PMC - PMC5383623
OTO - NOTNLM
OT  - Cerebral Palsy
OT  - Developmental Disabilities
OT  - Early Intervention
OT  - Rehabilitation
COIS- The authors have no potential conflicts of interest to disclose.
EDAT- 2017/04/06 06:00
MHDA- 2017/09/09 06:00
PMCR- 2017/05/01
CRDT- 2017/04/06 06:00
PHST- 2017/01/06 00:00 [received]
PHST- 2017/01/31 00:00 [accepted]
PHST- 2017/04/06 06:00 [entrez]
PHST- 2017/04/06 06:00 [pubmed]
PHST- 2017/09/09 06:00 [medline]
PHST- 2017/05/01 00:00 [pmc-release]
AID - 32.873 [pii]
AID - 10.3346/jkms.2017.32.5.873 [doi]
PST - ppublish
SO  - J Korean Med Sci. 2017 May;32(5):873-879. doi: 10.3346/jkms.2017.32.5.873.