PMID- 28379721
OWN - NLM
STAT- MEDLINE
DCOM- 20180207
LR  - 20180207
IS  - 1651-226X (Electronic)
IS  - 0284-186X (Linking)
VI  - 56
IP  - 9
DP  - 2017 Sep
TI  - Adverse events in hospitalised cancer patients: a comparison to a general 
      hospital population.
PG  - 1218-1223
LID - 10.1080/0284186X.2017.1309063 [doi]
AB  - BACKGROUND: Patients with cancer are often treated by many healthcare providers, 
      receive complex and potentially toxic treatments that can increase the risk for 
      iatrogenic harm. The aim of this study is to investigate whether hospitalised 
      cancer patients are at higher risk of adverse events (AEs) compared to a general 
      hospital population. MATERIAL AND METHODS: A total of 6720 patient records were 
      retrospectively reviewed comparing AEs in hospitalised cancer patients to a 
      general hospital population in Norway, using the IHI Global Trigger Tool method. 
      RESULTS: 24.2 percent of admissions for cancer patients had an AE compared to 
      17.4% of admissions of other patients (p < .001, rr 1.39, 95% CI 1.19-1.62). 
      However, cancer patients did not have a higher rate of AEs per 1000 patient days 
      compared to other patients, 37.1 vs. 36.0 (p = .65, rr 0.94, 95% CI 0.90-1.18). 
      No particular cancer category is at higher risk. The rate of AEs increases by 
      1.05 times for each day spent in hospital. For every year increase in age, the 
      risk for AEs increases by 1.3%. Cancer patients more often have hospital-acquired 
      infections, other surgical complications and AEs related to medications. 
      CONCLUSIONS: Because of higher age, longer length of stay and surgical treatment, 
      hospitalised cancer patients experience AEs more often than other patients.
FAU - Haukland, Ellinor Christin
AU  - Haukland EC
AD  - a Department of Oncology and Palliative Medicine , Nordland Hospital Trust , Bodo 
      , Norway.
AD  - b Department of Community Medicine , University of Tromso , Tromso , Norway.
FAU - von Plessen, Christian
AU  - von Plessen C
AD  - c Centre for Quality , Region of Southern Denmark , Middelfart , Denmark.
AD  - d Institute of Regional Health Research , University of Southern Denmark , Odense 
      , Denmark.
FAU - Nieder, Carsten
AU  - Nieder C
AD  - a Department of Oncology and Palliative Medicine , Nordland Hospital Trust , Bodo 
      , Norway.
AD  - e Department of Clinical Medicine , University of Tromso , Tromso , Norway.
FAU - Vonen, Barthold
AU  - Vonen B
AD  - b Department of Community Medicine , University of Tromso , Tromso , Norway.
AD  - f Centre for Clinical Documentation and Evaluation , Northern Norway Regional 
      Health Authority , Tromso , Norway.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20170405
PL  - Sweden
TA  - Acta Oncol
JT  - Acta oncologica (Stockholm, Sweden)
JID - 8709065
RN  - 0 (Antineoplastic Agents)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Antineoplastic Agents/*adverse effects
MH  - Drug-Related Side Effects and Adverse Reactions/*epidemiology/etiology
MH  - Female
MH  - Hospitalization/*statistics & numerical data
MH  - *Hospitals, General
MH  - Humans
MH  - Incidence
MH  - Length of Stay
MH  - Male
MH  - Medical Records
MH  - Middle Aged
MH  - Neoplasms/*drug therapy
MH  - Patient Safety
MH  - Prognosis
MH  - Retrospective Studies
MH  - Young Adult
EDAT- 2017/04/06 06:00
MHDA- 2018/02/08 06:00
CRDT- 2017/04/06 06:00
PHST- 2017/04/06 06:00 [pubmed]
PHST- 2018/02/08 06:00 [medline]
PHST- 2017/04/06 06:00 [entrez]
AID - 10.1080/0284186X.2017.1309063 [doi]
PST - ppublish
SO  - Acta Oncol. 2017 Sep;56(9):1218-1223. doi: 10.1080/0284186X.2017.1309063. Epub 
      2017 Apr 5.