PMID- 28382855
OWN - NLM
STAT- MEDLINE
DCOM- 20171218
LR  - 20220331
IS  - 1544-2217 (Electronic)
IS  - 0300-9858 (Linking)
VI  - 54
IP  - 4
DP  - 2017 Jul
TI  - Natural Infections With Pigeon Paramyxovirus Serotype 1: Pathologic Changes in 
      Eurasian Collared-Doves ( Streptopelia decaocto) and Rock Pigeons ( Columba 
      livia) in the United States.
PG  - 695-703
LID - 10.1177/0300985817695782 [doi]
AB  - Pigeon paramyxovirus serotype 1 (PPMV-1) is a globally distributed, virulent 
      member of the avian paramyxovirus serotype 1 serogroup that causes mortality in 
      columbiformes and poultry. Following introduction into the United States in the 
      mid-1980s, PPMV-1 rapidly spread causing numerous mortality events in Eurasian 
      collared-doves ( Streptopelia decaocto) (ECDOs) and rock pigeons ( Columba livia) 
      (ROPIs). The investigators reviewed pathological findings of 70 naturally 
      infected, free-ranging columbiforms from 25 different mortality events in the 
      United States. Immunohistochemistry targeting PPMV-1 nucleoprotein was used to 
      determine the tissue distribution of the virus in a subset of 17 birds from 10 of 
      the studied outbreaks. ECDOs (61 birds) and ROPIs (9 birds) were the only species 
      in which PPMV-1-associated disease was confirmed by viral isolation and presence 
      of histologic lesions. Acute to subacute tubulointerstitial nephritis and 
      necrotizing pancreatitis were the most frequent histologic lesions, with 
      immunolabeling of viral antigen in renal tubular epithelial cells and pancreatic 
      acinar epithelium. Lymphoid depletion of bursa of Fabricius and spleen was 
      common, but the presence of viral antigen in these organs was inconsistent among 
      infected birds. Hepatocellular necrosis was occasionally present with 
      immunolabeling of hypertrophic Kupffer cells, and immunopositive eosinophilic 
      intracytoplasmic inclusion bodies were present in hepatocytes of 1 ECDO. 
      Immunopositive lymphocytic choroiditis was present in 1 ECDO, while lymphocytic 
      meningoencephalitis was frequent in ROPIs in absence of immunolabeling. This 
      study demonstrates widespread presence of PPMV-1 antigen in association with 
      histologic lesions, confirming the lethal potential of this virus in these 
      particular bird species.
FAU - Isidoro-Ayza, M
AU  - Isidoro-Ayza M
AD  - 1 Department of Pathobiological Sciences, School of Veterinary Medicine, 
      University of Wisconsin, Madison, WI, USA.
FAU - Afonso, C L
AU  - Afonso CL
AD  - 2 Southeast Poultry Research Laboratory, Agricultural Research Service, US 
      Department of Agriculture, Athens, GA, USA.
FAU - Stanton, J B
AU  - Stanton JB
AD  - 3 Department of Pathology, College of Veterinary Medicine, University of Georgia, 
      Athens, GA, USA.
FAU - Knowles, S
AU  - Knowles S
AD  - 4 National Wildlife Health Center-US Geological Survey, Madison, WI, USA.
FAU - Ip, H S
AU  - Ip HS
AD  - 4 National Wildlife Health Center-US Geological Survey, Madison, WI, USA.
FAU - White, C L
AU  - White CL
AD  - 4 National Wildlife Health Center-US Geological Survey, Madison, WI, USA.
FAU - Fenton, H
AU  - Fenton H
AD  - 5 Southeastern Cooperative Wildlife Disease Study, Athens, GA, USA.
FAU - Ruder, M G
AU  - Ruder MG
AD  - 5 Southeastern Cooperative Wildlife Disease Study, Athens, GA, USA.
FAU - Dolinski, A C
AU  - Dolinski AC
AD  - 6 Department of Fisheries and Wildlife, Michigan State University, East Lansing, 
      MI, USA.
FAU - Lankton, J
AU  - Lankton J
AD  - 4 National Wildlife Health Center-US Geological Survey, Madison, WI, USA.
LA  - eng
PT  - Journal Article
DEP - 20170406
PL  - United States
TA  - Vet Pathol
JT  - Veterinary pathology
JID - 0312020
SB  - IM
MH  - Animals
MH  - Animals, Wild/virology
MH  - Bursa of Fabricius/pathology/virology
MH  - Columbidae/*virology
MH  - Disease Outbreaks/veterinary
MH  - Nephritis, Interstitial/pathology/veterinary/virology
MH  - Newcastle Disease/epidemiology/pathology/*virology
MH  - *Newcastle disease virus/isolation & purification
MH  - Spleen/pathology/virology
MH  - United States/epidemiology
OTO - NOTNLM
OT  - Eurasian collared-dove
OT  - Newcastle disease virus
OT  - avian paramyxovirus serotype 1
OT  - histopathology
OT  - immunohistochemistry
OT  - pathogenesis
OT  - pigeon paramyxovirus serotype 1
OT  - rock pigeon
EDAT- 2017/04/07 06:00
MHDA- 2017/12/19 06:00
CRDT- 2017/04/07 06:00
PHST- 2017/04/07 06:00 [pubmed]
PHST- 2017/12/19 06:00 [medline]
PHST- 2017/04/07 06:00 [entrez]
AID - 10.1177/0300985817695782 [doi]
PST - ppublish
SO  - Vet Pathol. 2017 Jul;54(4):695-703. doi: 10.1177/0300985817695782. Epub 2017 Apr 
      6.