PMID- 28389122
OWN - NLM
STAT- MEDLINE
DCOM- 20180321
LR  - 20180321
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 241
DP  - 2017 Aug 15
TI  - Venoarterial extracorporeal membrane oxygenation after coronary artery bypass 
      grafting: Results of a multicenter study.
PG  - 109-114
LID - S0167-5273(16)34341-8 [pii]
LID - 10.1016/j.ijcard.2017.03.120 [doi]
AB  - BACKGROUND: The evidence of the benefits of using venoarterial extracorporeal 
      membrane oxygenation (VA-ECMO) after coronary artery bypass grafting (CABG) is 
      scarce. METHODS: We analyzed the outcomes of patients who received VA-ECMO 
      therapy due to cardiac or respiratory failure after isolated CABG in 12 centers 
      between 2005 and 2016. Patients treated preoperatively with ECMO were excluded 
      from this study. RESULTS: VA-ECMO was employed in 148 patients after CABG for 
      median of 5.0days (mean, 6.4, SD 5.6days). In-hospital mortality was 64.2%. 
      Pooled in-hospital mortality was 65.9% without significant heterogeneity between 
      the centers (I(2) 8.6%). The proportion of VA-ECMO in each center did not affect 
      in-hospital mortality (p=0.861). No patients underwent heart transplantation and 
      six patients received a left ventricular assist device. Logistic regression 
      showed that creatinine clearance (p=0.004, OR 0.98, 95% CI 0.97-0.99), pulmonary 
      disease (p=0.018, OR 4.42, 95% CI 1.29-15.15) and pre-VA-ECMO blood lactate 
      (p=0.015, OR 1.10, 95% CI 1.02-1.18) were independent baseline predictors of 
      in-hospital mortality. One-, 2-, and 3-year survival was 31.0%, 27.9%, and 26.1%, 
      respectively. CONCLUSIONS: One third of patients with need for VA-ECMO after CABG 
      survive to discharge. In view of the burden of resources associated with VA-ECMO 
      treatment and the limited number of patients surviving to discharge, further 
      studies are needed to identify patients who may benefit the most from this 
      treatment.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Biancari, Fausto
AU  - Biancari F
AD  - Department of Surgery, Oulu University Hospital, Oulu, Finland. Electronic 
      address: fausto.biancari@oulu.fi.
FAU - Dalen, Magnus
AU  - Dalen M
AD  - Department of Molecular Medicine and Surgery, Department of Cardiothoracic 
      Surgery and Anesthesiology, Karolinska Institutet, Karolinska University 
      Hospital, Stockholm, Sweden.
FAU - Perrotti, Andrea
AU  - Perrotti A
AD  - Department of Thoracic and Cardio-Vascular Surgery, University Hospital Jean 
      Minjoz, Besancon, France.
FAU - Fiore, Antonio
AU  - Fiore A
AD  - Department of Cardiothoracic Surgery, Henri Mondor University Hospital, AP-HP, 
      Paris-Est University, Creteil, France.
FAU - Reichart, Daniel
AU  - Reichart D
AD  - Hamburg University Heart Center, Hamburg, Germany.
FAU - Khodabandeh, Sorosh
AU  - Khodabandeh S
AD  - Department of Molecular Medicine and Surgery, Department of Cardiothoracic 
      Surgery and Anesthesiology, Karolinska Institutet, Karolinska University 
      Hospital, Stockholm, Sweden.
FAU - Gulbins, Helmut
AU  - Gulbins H
AD  - Hamburg University Heart Center, Hamburg, Germany.
FAU - Zipfel, Svante
AU  - Zipfel S
AD  - Hamburg University Heart Center, Hamburg, Germany.
FAU - Al Shakaki, Mosab
AU  - Al Shakaki M
AD  - Department of Cardiothoracic Surgery, University Hospital Muenster, Muenster, 
      Germany.
FAU - Welp, Henryk
AU  - Welp H
AD  - Department of Cardiothoracic Surgery, University Hospital Muenster, Muenster, 
      Germany.
FAU - Vezzani, Antonella
AU  - Vezzani A
AD  - Division of Cardiac Surgery, University of Parma, Parma, Italy.
FAU - Gherli, Tiziano
AU  - Gherli T
AD  - Division of Cardiac Surgery, University of Parma, Parma, Italy.
FAU - Lommi, Jaakko
AU  - Lommi J
AD  - Cardiac Surgery, Heart and Lung Center, Helsinki University Central Hospital, 
      Helsinki, Finland.
FAU - Juvonen, Tatu
AU  - Juvonen T
AD  - Cardiac Surgery, Heart and Lung Center, Helsinki University Central Hospital, 
      Helsinki, Finland.
FAU - Svenarud, Peter
AU  - Svenarud P
AD  - Department of Molecular Medicine and Surgery, Department of Cardiothoracic 
      Surgery and Anesthesiology, Karolinska Institutet, Karolinska University 
      Hospital, Stockholm, Sweden.
FAU - Chocron, Sidney
AU  - Chocron S
AD  - Department of Thoracic and Cardio-Vascular Surgery, University Hospital Jean 
      Minjoz, Besancon, France.
FAU - Verhoye, Jean Philippe
AU  - Verhoye JP
AD  - Division of Cardiothoracic and Vascular Surgery, Pontchaillou University 
      Hospital, Rennes, France.
FAU - Bounader, Karl
AU  - Bounader K
AD  - Division of Cardiothoracic and Vascular Surgery, Pontchaillou University 
      Hospital, Rennes, France.
FAU - Gatti, Giuseppe
AU  - Gatti G
AD  - Division of Cardiac Surgery, Ospedali Riuniti, Trieste, Italy.
FAU - Gabrielli, Marco
AU  - Gabrielli M
AD  - Division of Cardiac Surgery, Ospedali Riuniti, Trieste, Italy.
FAU - Saccocci, Matteo
AU  - Saccocci M
AD  - Department of Cardiac Surgery, Centro Cardiologico-Fondazione Monzino IRCCS, 
      University of Milan, Milan, Italy.
FAU - Kinnunen, Eeva-Maija
AU  - Kinnunen EM
AD  - Department of Surgery, Oulu University Hospital, Oulu, Finland.
FAU - Onorati, Francesco
AU  - Onorati F
AD  - Division of Cardiovascular Surgery, Verona University Hospital, Verona, Italy.
FAU - Santarpino, Giuseppe
AU  - Santarpino G
AD  - Cardiovascular Center, Paracelsus Medical University, Nuremberg, Germany.
FAU - Alkhamees, Khalid
AU  - Alkhamees K
AD  - Saud Al-Babtain Cardiac Center, Ministry of Health, Dammam, Saudi Arabia.
FAU - Ruggieri, Vito G
AU  - Ruggieri VG
AD  - Division of Cardiothoracic and Vascular Surgery, Pontchaillou University 
      Hospital, Rennes, France.
FAU - Dell'Aquila, Angelo M
AU  - Dell'Aquila AM
AD  - Department of Cardiothoracic Surgery, University Hospital Muenster, Muenster, 
      Germany.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20170328
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Aged
MH  - Coronary Artery Bypass/mortality/*trends
MH  - Extracorporeal Membrane Oxygenation/mortality/*trends
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Failure/mortality/*surgery
MH  - Hospital Mortality/*trends
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Patient Discharge/*trends
OTO - NOTNLM
OT  - CABG
OT  - Coronary artery bypass
OT  - ECLS
OT  - ECMO
OT  - Extracorporeal life support
OT  - Extracorporeal membrane oxygenation
OT  - Heart failure
OT  - Post-cardiotomy
EDAT- 2017/04/09 06:00
MHDA- 2018/03/22 06:00
CRDT- 2017/04/09 06:00
PHST- 2016/12/07 00:00 [received]
PHST- 2017/02/16 00:00 [revised]
PHST- 2017/03/24 00:00 [accepted]
PHST- 2017/04/09 06:00 [pubmed]
PHST- 2018/03/22 06:00 [medline]
PHST- 2017/04/09 06:00 [entrez]
AID - S0167-5273(16)34341-8 [pii]
AID - 10.1016/j.ijcard.2017.03.120 [doi]
PST - ppublish
SO  - Int J Cardiol. 2017 Aug 15;241:109-114. doi: 10.1016/j.ijcard.2017.03.120. Epub 
      2017 Mar 28.