PMID- 28390742
OWN - NLM
STAT- MEDLINE
DCOM- 20180403
LR  - 20180403
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 240
DP  - 2017 Aug 1
TI  - Long term prognosis of atrial fibrillation in ST-elevation myocardial infarction 
      patients undergoing percutaneous coronary intervention.
PG  - 228-233
LID - S0167-5273(16)32197-0 [pii]
LID - 10.1016/j.ijcard.2017.03.060 [doi]
AB  - BACKGROUND: Atrial fibrillation (AF) is a well-known complication in the setting 
      of ST elevation myocardial infarction (STEMI). Data on the long-term prognostic 
      implications of New-Onset AF (NOAF) complicating STEMI in the era of complete 
      revascularization remains controversial. Our aim therefore was to evaluate the 
      long-term prognosis of prior AF (pAF) and new-onset AF (NOAF) in STEMI patients 
      undergoing percutaneous coronary intervention (PCI). METHODS: We studied 1657 
      consecutive STEMI patients hospitalized in the cardiac intensive care unit during 
      2008-2014. We reviewed patient records for the occurrence of pAF and NOAF. NOAF 
      was defined as AF occurring within 30days of the STEMI episode. Patients were 
      followed for a mean period of 3.4+/-2.1years. RESULTS: Within our cohort 77 (4.6%) 
      patients had pAF and 47 (2.8%) had NOAF. Patients with any AF were older and had 
      a reduced systolic ejection fraction. Thirty-day mortality and all-cause 
      mortality rates were significantly higher in patients with pAF in comparison to 
      those without AF (9.1% vs. 2.2% p<0.001 and 31.2% vs. 9.4%, p<0.001, 
      respectively). NOAF showed a trend for increased all-cause mortality (17% vs. 
      9.1%, p=0.07) and 30-days mortality (6.4% vs. 2.1%. p=0.09). In a multivariate 
      regression model, pAF but not NOAF was a predictor of mortality throughout the 
      follow-up period (HR 2.02, 95% CI 1.2 to 3.1, p=0.005 and HR 1.1, 95% CI 0.56 to 
      2.2, p=0.75, respectively). CONCLUSIONS: Prior AF and not new-onset AF is an 
      independent predictor of both short and long term mortality in patients treated 
      with PCI.
CI  - Copyright (c) 2017. Published by Elsevier B.V.
FAU - Topaz, Guy
AU  - Topaz G
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel.
FAU - Flint, Nir
AU  - Flint N
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel.
FAU - Steinvil, Arie
AU  - Steinvil A
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel.
FAU - Finkelstein, Arik
AU  - Finkelstein A
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel.
FAU - Banai, Shmuel
AU  - Banai S
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel.
FAU - Keren, Gad
AU  - Keren G
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel.
FAU - Shacham, Yacov
AU  - Shacham Y
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel.
FAU - Yankelson, Lior
AU  - Yankelson L
AD  - Tel-Aviv Sourasky Medical Center and Sackler-School of Medicine, Tel Aviv 
      University, Israel; Leon H. Charney Division of Cardiology, New York University 
      Langone Medical Center, New York, New York. Electronic address: 
      lioryan@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20170316
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
CIN - Int J Cardiol. 2017 Nov 1;246:53. PMID: 28867014
MH  - Aged
MH  - Aged, 80 and over
MH  - Atrial Fibrillation/*diagnosis/*mortality/surgery
MH  - Cohort Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mortality/trends
MH  - Percutaneous Coronary Intervention/*mortality/trends
MH  - Prognosis
MH  - Prospective Studies
MH  - Registries
MH  - Retrospective Studies
MH  - ST Elevation Myocardial Infarction/*diagnosis/*mortality/surgery
MH  - Stroke Volume/physiology
MH  - Time Factors
OTO - NOTNLM
OT  - Atrial fibrillation (AF)
OT  - Mortality
OT  - Percutaneous coronary intervention (PCI)
OT  - ST elevation MI (STEMI)
EDAT- 2017/04/10 06:00
MHDA- 2018/04/04 06:00
CRDT- 2017/04/10 06:00
PHST- 2016/09/11 00:00 [received]
PHST- 2017/03/15 00:00 [accepted]
PHST- 2017/04/10 06:00 [pubmed]
PHST- 2018/04/04 06:00 [medline]
PHST- 2017/04/10 06:00 [entrez]
AID - S0167-5273(16)32197-0 [pii]
AID - 10.1016/j.ijcard.2017.03.060 [doi]
PST - ppublish
SO  - Int J Cardiol. 2017 Aug 1;240:228-233. doi: 10.1016/j.ijcard.2017.03.060. Epub 
      2017 Mar 16.