PMID- 28402180
OWN - NLM
STAT- MEDLINE
DCOM- 20171016
LR  - 20171016
IS  - 1944-0057 (Electronic)
IS  - 1944-0057 (Linking)
VI  - 34
IP  - 7
DP  - 2017 Jul
TI  - Analytical determination of bisphenol A (BPA) and bisphenol analogues in paper 
      products by GC-MS/MS.
PG  - 1225-1238
LID - 10.1080/19440049.2017.1319076 [doi]
AB  - Bisphenol A (BPA; 4-[2-(4-hydroxyphenyl)propan-2-yl]phenol), a suspected 
      endocrine disruptor with a weak estrogenic activity, is used in a variety of 
      consumer products, including food-contact materials made of paper and cardboard 
      products. Due to restrictions on the use of BPA because of its potential health 
      risks, BPA is gradually being replaced by other bisphenols because no limitations 
      exist for these substances. This study presents a method for the simultaneous 
      analysis of BPA, bisphenol AF (BPAF), bisphenol B (BPB), bisphenol E (BPE), 
      bisphenol F (BPF) and bisphenol S (BPS) in paper and board products using gas 
      chromatography-tandem mass spectrometry (GC-MS/MS). Paper samples were extracted 
      by liquid extraction, as well as by Folch extraction, derivatised with 
      N,O-bis(trimethylsilyl)trifluoroacetamide (BSTFA) and the results compared. The 
      developed method showed good linearity (R(2) > 0.9965) and precision, yielding 
      relative standard deviations (RSDs) of less than 16.6% for reproducibility and 
      19.8% for repeatability. The limits of detection and limits of quantification for 
      the different bisphenols ranged from 0.23 to 2.70 microg kg(-)(1) paper and from 0.78 
      to 9.10 microg kg(-)(1) paper, respectively. Analysis of different paper products 
      (recycled, virgin fibre) showed that all the analysed bisphenols were present in 
      the samples, except for BPAF and BPB. A calculation of the 'worst-case' scenario 
      assuming a maximum potential migration of 100% of the analytes into food showed 
      that the analysed products can be assumed to be safe regarding the migration of 
      bisphenols.
FAU - Jurek, A
AU  - Jurek A
AD  - a Food Chemistry and Human Sensory Analysis, Institute of Analytical Chemistry 
      and Food Chemistry , Graz University of Technology , Graz , Austria.
FAU - Leitner, E
AU  - Leitner E
AD  - a Food Chemistry and Human Sensory Analysis, Institute of Analytical Chemistry 
      and Food Chemistry , Graz University of Technology , Graz , Austria.
LA  - eng
PT  - Journal Article
DEP - 20170517
PL  - England
TA  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess
JT  - Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & 
      risk assessment
JID - 101485040
RN  - 0 (Benzhydryl Compounds)
RN  - 0 (Phenols)
RN  - MLT3645I99 (bisphenol A)
SB  - IM
MH  - Benzhydryl Compounds/*analysis
MH  - Chromatography, Gas
MH  - *Paper
MH  - Phenols/*analysis
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - Bisphenol A (BPA)
OT  - bisphenol analogues
OT  - derivatisation
OT  - food packaging
OT  - gas chromatography-tandem mass spectrometry(GC-MS/MS)
OT  - paper and cardboard
EDAT- 2017/04/13 06:00
MHDA- 2017/10/17 06:00
CRDT- 2017/04/13 06:00
PHST- 2017/04/13 06:00 [pubmed]
PHST- 2017/10/17 06:00 [medline]
PHST- 2017/04/13 06:00 [entrez]
AID - 10.1080/19440049.2017.1319076 [doi]
PST - ppublish
SO  - Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2017 
      Jul;34(7):1225-1238. doi: 10.1080/19440049.2017.1319076. Epub 2017 May 17.