PMID- 28403080 OWN - NLM STAT- MEDLINE DCOM- 20170428 LR - 20210109 IS - 1536-5964 (Electronic) IS - 0025-7974 (Print) IS - 0025-7974 (Linking) VI - 96 IP - 15 DP - 2017 Apr TI - Characteristics of diurnal ventricular premature complex variation in right ventricular outflow tract arrhythmias after catheter ablation. PG - e6516 LID - 10.1097/MD.0000000000006516 [doi] LID - e6516 AB - Diurnal variations in ventricular tachyarrhythmias (VAs) have been demonstrated in idiopathic arrhythmogenic heart disease. The electrophysiological characteristics of diurnal variations in idiopathic right ventricular outflow tract (RVOT) VA have not previously been elucidated. Sixty-two consecutive patients undergoing catheter ablation for idiopathic RVOT VA (mean age: 42.8 +/- 12.3 years, 35 females) were enrolled. The diurnal variation type (group 1, n = 36) was defined as those patients who had most ventricular premature contractions (VPCs) during the night hours by preprocedure Holter recordings. Group 2 (n = 26) was defined as those patients who did not have significant VPC variations. The baseline characteristics and electrophysiological properties were collected and analyzed, and the rates of recurrence after catheter ablation were compared between the 2 groups. In this study, heart rate variability analysis demonstrated lower low frequency/high frequency ratios in group 1 than in group 2 (3.95 +/- 3.08 vs 6.26 +/- 5.33; P = 0.042). There were no significant differences in baseline characteristics, echocardiography and electrophysiological characteristics between the 2 groups. During a mean follow-up period of 13.5 +/- 11.0 months, a total of 16 patients had VA recurrences, including 13 patients from group 1 and 3 patients from group 2 (36.1% vs 12.5%, P = 0.039). This study demonstrated the effect of the autonomic nervous system in idiopathic RVOT VAs and that the diurnal variation type leads to a higher recurrence rate after catheter ablation. FAU - Jhuo, Shih-Jie AU - Jhuo SJ AD - Division of Cardiology, Kaohsiung Medical University Hospital Division of Cardiology, Taipei Veterans General Hospital Institute of Clinical Medicine, and Cardiovascular Research Center, Faculty of Medicine, College of Medicine, National Yang-Ming Medical University, Taipei Department of Internal Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan. FAU - Lo, Li-Wei AU - Lo LW FAU - Chang, Shih-Lin AU - Chang SL FAU - Lin, Yenn-Jiang AU - Lin YJ FAU - Chung, Fa-Po AU - Chung FP FAU - Hu, Yu-Feng AU - Hu YF FAU - Chao, Tze-Fan AU - Chao TF FAU - Tuan, Ta-Chuan AU - Tuan TC FAU - Liao, Jo-Nan AU - Liao JN FAU - Lin, Chin-Yu AU - Lin CY FAU - Chang, Yao-Ting AU - Chang YT FAU - Lin, Chung-Hsing AU - Lin CH FAU - Walia, Rohit AU - Walia R FAU - Te, Abigail Louise D AU - Te ALD FAU - Yamada, Shinya AU - Yamada S FAU - Raharjo, Sunu Budhi AU - Raharjo SB FAU - Tang, Wei-Hua AU - Tang WH FAU - Lee, Kun-Tai AU - Lee KT FAU - Lai, Wen-Ter AU - Lai WT FAU - Chen, Shih-Ann AU - Chen SA LA - eng PT - Journal Article PL - United States TA - Medicine (Baltimore) JT - Medicine JID - 2985248R SB - IM MH - Adult MH - Autonomic Nervous System/physiopathology MH - *Catheter Ablation MH - Circadian Rhythm MH - Echocardiography MH - Electrocardiography MH - Female MH - Follow-Up Studies MH - Heart Rate MH - Humans MH - Male MH - Middle Aged MH - Postoperative Period MH - Recurrence MH - Tachycardia, Ventricular/*physiopathology/surgery MH - Treatment Outcome MH - *Ventricular Function, Right MH - Ventricular Premature Complexes/*physiopathology/surgery PMC - PMC5403077 COIS- The authors have no conflicts of interest to disclose. EDAT- 2017/04/14 06:00 MHDA- 2017/04/30 06:00 PMCR- 2017/04/14 CRDT- 2017/04/14 06:00 PHST- 2017/04/14 06:00 [entrez] PHST- 2017/04/14 06:00 [pubmed] PHST- 2017/04/30 06:00 [medline] PHST- 2017/04/14 00:00 [pmc-release] AID - 00005792-201704140-00013 [pii] AID - MD-D-16-07021 [pii] AID - 10.1097/MD.0000000000006516 [doi] PST - ppublish SO - Medicine (Baltimore). 2017 Apr;96(15):e6516. doi: 10.1097/MD.0000000000006516.