PMID- 28407284
OWN - NLM
STAT- MEDLINE
DCOM- 20180131
LR  - 20181202
IS  - 1098-108X (Electronic)
IS  - 0276-3478 (Linking)
VI  - 50
IP  - 8
DP  - 2017 Aug
TI  - Executive functions in adolescents with binge-eating disorder and obesity.
PG  - 933-941
LID - 10.1002/eat.22714 [doi]
AB  - OBJECTIVE: Binge-eating disorder (BED) in adults is associated with alterations 
      in executive functions (EF) and obesity. Much less is known about these 
      relationships in adolescents, including whether poor EF are associated with 
      eating disorder psychopathology and/or elevated body mass index. This study 
      examined EF in response to neutral stimuli in youth with BED. METHOD: Adolescents 
      with BED and obesity (n = 22), individually matched adolescents with obesity 
      (n = 22), and normal weight (n = 22) completed neuropsychological tests targeting 
      inhibition (Color-Word Interference Test), sustained attention (D2 Concentration 
      Endurance Test), cognitive flexibility (Comprehensive Trail Making Test), and 
      decision-making (Iowa Gambling Task). RESULTS: Adolescents with BED and obesity 
      displayed significantly poorer inhibitory control compared to normal-weight 
      adolescents. This effect persisted after controlling for the level of secondary 
      education. However, initial differences between adolescents with obesity and 
      normal-weight controls regarding inhibitory control and sustained attention 
      vanished after controlling for education. The three groups did not differ 
      regarding cognitive flexibility and decision-making. Moreover, adolescents with 
      BED and obesity did not perform worse than adolescents with obesity on any of the 
      neuropsychological tests. DISCUSSION: Overall, our results indicate that 
      adolescent BED is associated with only a few alterations in general EF, 
      specifically inhibitory control, and underline BED and educational level as 
      confounding factors in neuropsychological research on obesity. To further 
      delineate EF profiles of adolescents with BED, future research should focus on EF 
      in response to disorder-related stimuli and experimental settings with high 
      ecological validity.
CI  - (c) 2017 Wiley Periodicals, Inc.
FAU - Kittel, Rebekka
AU  - Kittel R
AUID- ORCID: 0000-0002-1506-2218
AD  - Department of Medical Psychology and Medical Sociology, Department of 
      Psychosomatic Medicine and Psychotherapy, Leipzig University Medical Center, 
      Integrated Research and Treatment Center Adiposity Diseases, 04103, Leipzig, 
      Germany.
FAU - Schmidt, Ricarda
AU  - Schmidt R
AD  - Department of Medical Psychology and Medical Sociology, Department of 
      Psychosomatic Medicine and Psychotherapy, Leipzig University Medical Center, 
      Integrated Research and Treatment Center Adiposity Diseases, 04103, Leipzig, 
      Germany.
FAU - Hilbert, Anja
AU  - Hilbert A
AD  - Department of Medical Psychology and Medical Sociology, Department of 
      Psychosomatic Medicine and Psychotherapy, Leipzig University Medical Center, 
      Integrated Research and Treatment Center Adiposity Diseases, 04103, Leipzig, 
      Germany.
LA  - eng
PT  - Journal Article
DEP - 20170413
PL  - United States
TA  - Int J Eat Disord
JT  - The International journal of eating disorders
JID - 8111226
SB  - IM
MH  - Adolescent
MH  - Binge-Eating Disorder/*psychology
MH  - *Executive Function
MH  - Female
MH  - Humans
MH  - Male
MH  - Obesity/*psychology
OTO - NOTNLM
OT  - adolescents
OT  - binge-eating disorder
OT  - executive functions
OT  - inhibitory control
OT  - obesity
EDAT- 2017/04/14 06:00
MHDA- 2018/02/01 06:00
CRDT- 2017/04/14 06:00
PHST- 2016/09/08 00:00 [received]
PHST- 2017/03/20 00:00 [revised]
PHST- 2017/03/26 00:00 [accepted]
PHST- 2017/04/14 06:00 [pubmed]
PHST- 2018/02/01 06:00 [medline]
PHST- 2017/04/14 06:00 [entrez]
AID - 10.1002/eat.22714 [doi]
PST - ppublish
SO  - Int J Eat Disord. 2017 Aug;50(8):933-941. doi: 10.1002/eat.22714. Epub 2017 Apr 
      13.