PMID- 28408778
OWN - NLM
STAT- MEDLINE
DCOM- 20171011
LR  - 20181113
IS  - 1928-9022 (Electronic)
IS  - 0830-9000 (Print)
IS  - 0830-9000 (Linking)
VI  - 81
IP  - 2
DP  - 2017 Apr
TI  - Concurrent vaccination of boars with type 1 and type 2 porcine reproductive and 
      respiratory syndrome virus (PRRSV) reduces seminal shedding of type 1 and type 2 
      PRRSV.
PG  - 108-117
AB  - The objective of the present study was to determine the effect of concurrent 
      vaccination of boars with type 1 and type 2 porcine reproductive and respiratory 
      syndrome virus (PRRSV) on seminal shedding of both genotypes. The boars tolerated 
      well concurrent administration of 2 commercial PRRSV vaccines, and no adverse 
      reactions were observed. No interference in the humoral immune response (measured 
      as the level of anti-PRRSV antibodies) or the cell-mediated immune response 
      (measured as the level of PRRSV-specific interferon-gamma-secreting cells) was 
      observed after concurrent administration compared with single administration of 
      the same vaccines. Concurrent vaccination significantly reduced the load of type 
      1 and type 2 PRRSV in blood and semen after singular (type 1 or type 2) and dual 
      (type 1 and type 2) PRRSV challenge, and it did not significantly affect the 
      efficacy of each vaccine. The results demonstrate that concurrent vaccination of 
      boars with type 1 and type 2 PRRSV reduces shedding of both genotypes in semen.
FAU - Jeong, Jiwoon
AU  - Jeong J
AD  - Seoul National University, College of Veterinary Medicine, Department of 
      Veterinary Pathology, 1 Gwanak-ro, Gwanak-gu, 151-742, Seoul, Republic of Korea.
FAU - Park, Changhoon
AU  - Park C
AD  - Seoul National University, College of Veterinary Medicine, Department of 
      Veterinary Pathology, 1 Gwanak-ro, Gwanak-gu, 151-742, Seoul, Republic of Korea.
FAU - Kang, Ikjae
AU  - Kang I
AD  - Seoul National University, College of Veterinary Medicine, Department of 
      Veterinary Pathology, 1 Gwanak-ro, Gwanak-gu, 151-742, Seoul, Republic of Korea.
FAU - Park, Su-Jin
AU  - Park SJ
AD  - Seoul National University, College of Veterinary Medicine, Department of 
      Veterinary Pathology, 1 Gwanak-ro, Gwanak-gu, 151-742, Seoul, Republic of Korea.
FAU - Chae, Chanhee
AU  - Chae C
AD  - Seoul National University, College of Veterinary Medicine, Department of 
      Veterinary Pathology, 1 Gwanak-ro, Gwanak-gu, 151-742, Seoul, Republic of Korea.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - Canada
TA  - Can J Vet Res
JT  - Canadian journal of veterinary research = Revue canadienne de recherche 
      veterinaire
JID - 8607793
RN  - 0 (Antibodies, Viral)
RN  - 0 (Viral Vaccines)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/blood
MH  - Male
MH  - Porcine Reproductive and Respiratory Syndrome/blood/*prevention & 
      control/virology
MH  - Porcine respiratory and reproductive syndrome virus/*classification/physiology
MH  - Semen/*virology
MH  - Swine
MH  - Viral Vaccines/*immunology
MH  - *Virus Shedding
PMC - PMC5370536
EDAT- 2017/04/15 06:00
MHDA- 2017/10/12 06:00
PMCR- 2017/10/01
CRDT- 2017/04/15 06:00
PHST- 2016/07/04 00:00 [received]
PHST- 2016/10/21 00:00 [accepted]
PHST- 2017/04/15 06:00 [entrez]
PHST- 2017/04/15 06:00 [pubmed]
PHST- 2017/10/12 06:00 [medline]
PHST- 2017/10/01 00:00 [pmc-release]
AID - cjvr_02_108 [pii]
PST - ppublish
SO  - Can J Vet Res. 2017 Apr;81(2):108-117.