PMID- 28410684
OWN - NLM
STAT- MEDLINE
DCOM- 20170427
LR  - 20170427
IS  - 1724-191X (Electronic)
IS  - 1120-1797 (Linking)
VI  - 36
DP  - 2017 Apr
TI  - Knowledge-based treatment planning: An inter-technique and inter-system 
      feasibility study for prostate cancer.
PG  - 38-45
LID - S1120-1797(17)30056-X [pii]
LID - 10.1016/j.ejmp.2017.03.002 [doi]
AB  - PURPOSE: Helical Tomotherapy (HT) plans were used to create two RapidPlan 
      knowledge-based (KB) models to generate plans with different techniques and to 
      guide the optimization in a different treatment planning system for prostate 
      plans. Feasibility and performance of these models were evaluated. MATERIAL AND 
      METHODS: two sets of 35 low risk (LR) and 30 intermediate risk (IR) prostate 
      cancer cases who underwent HT treatments were selected to train RapidPlan models. 
      The KB predicted constraints were used to perform new 20KB plans using RapidArc 
      technique (KB-RA) (inter-technique validation), and to optimise 20 new HT (KB-HT) 
      plans in the Tomoplan (inter-system validation). For each validation modality, KB 
      plans were benchmarked with the manual plans created by an expert planner (EP). 
      RESULTS: RapidPlan was successfully configured using HT plans. The KB-RA plans 
      fulfilled the clinical dose-volume requirements in 100% and 92% of cases for 
      planning target volumes (PTVs) and organs at risk (OARs), respectively. For KB-HT 
      plans these percentages were found to be a bit lower: 90% for PTVs and 86% for 
      OARs. In comparison to EP plans, the KB-RA plans produced higher bladder doses 
      for both LR and IR, and higher rectum doses for LR. KB-HT and EP plans produced 
      similar results. CONCLUSION: RapidPlan can be trained to create models by using 
      plans of a different treatment modality. These models were suitable for 
      generating clinically acceptable plans for inter-technique and inter-system 
      applications. The use of KB models based on plans of consolidated technique could 
      be useful with a new treatment modality.
CI  - Copyright (c) 2017 Associazione Italiana di Fisica Medica. Published by Elsevier 
      Ltd. All rights reserved.
FAU - Cagni, Elisabetta
AU  - Cagni E
AD  - Medical Physics Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: 
      elisabetta.cagni@asmn.re.it.
FAU - Botti, Andrea
AU  - Botti A
AD  - Medical Physics Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: andrea.botti@asmn.re.it.
FAU - Micera, Renato
AU  - Micera R
AD  - Radiotherapy Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: renato.micera@asmn.re.it.
FAU - Galeandro, Maria
AU  - Galeandro M
AD  - Radiotherapy Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: 
      maria.galeandro@asmn.re.it.
FAU - Sghedoni, Roberto
AU  - Sghedoni R
AD  - Medical Physics Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: 
      roberto.sghedoni@asmn.re.it.
FAU - Orlandi, Matteo
AU  - Orlandi M
AD  - Medical Physics Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: 
      matteo.orlandi@asmn.re.it.
FAU - Iotti, Cinzia
AU  - Iotti C
AD  - Radiotherapy Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: 
      maria.galeandro@asmn.re.it.
FAU - Cozzi, Luca
AU  - Cozzi L
AD  - Radiotherapy and Radiosurgery Department, Istituto Clinico Humanitas, Rozzano, 
      Milan, Italy. Electronic address: luca.cozzi@varian.com.
FAU - Iori, Mauro
AU  - Iori M
AD  - Medical Physics Unit, Department of Advanced Technology, Arcispedale Santa Maria 
      Nuova, IRCCS, Reggio Emilia, Italy. Electronic address: mauro.iori@asmn.re.it.
LA  - eng
PT  - Journal Article
DEP - 20170317
PL  - Italy
TA  - Phys Med
JT  - Physica medica : PM : an international journal devoted to the applications of 
      physics to medicine and biology : official journal of the Italian Association of 
      Biomedical Physics (AIFB)
JID - 9302888
SB  - IM
MH  - Feasibility Studies
MH  - Humans
MH  - Male
MH  - *Models, Theoretical
MH  - Prostatic Neoplasms/*radiotherapy
MH  - Radiometry
MH  - Radiotherapy Planning, Computer-Assisted/*methods
MH  - Risk
OTO - NOTNLM
OT  - Knowledge based
OT  - Planning Automation
OT  - Prostate
OT  - Rapidarc
OT  - Tomotherapy
EDAT- 2017/04/16 06:00
MHDA- 2017/04/28 06:00
CRDT- 2017/04/16 06:00
PHST- 2016/09/27 00:00 [received]
PHST- 2017/03/03 00:00 [revised]
PHST- 2017/03/07 00:00 [accepted]
PHST- 2017/04/16 06:00 [entrez]
PHST- 2017/04/16 06:00 [pubmed]
PHST- 2017/04/28 06:00 [medline]
AID - S1120-1797(17)30056-X [pii]
AID - 10.1016/j.ejmp.2017.03.002 [doi]
PST - ppublish
SO  - Phys Med. 2017 Apr;36:38-45. doi: 10.1016/j.ejmp.2017.03.002. Epub 2017 Mar 17.