PMID- 28412612
OWN - NLM
STAT- MEDLINE
DCOM- 20180119
LR  - 20191210
IS  - 1872-7123 (Electronic)
IS  - 0165-1781 (Linking)
VI  - 253
DP  - 2017 Jul
TI  - Impairment in Social Functioning differentiates youth meeting Ultra-High Risk for 
      psychosis criteria from other mental health help-seekers: A validation of the 
      Italian version of the Global Functioning: Social and Global Functioning: Role 
      scales.
PG  - 296-302
LID - S0165-1781(16)31520-7 [pii]
LID - 10.1016/j.psychres.2017.04.008 [doi]
AB  - Social and occupational impairments are present in the schizophrenia prodrome, 
      and poor social functioning predicts transition to psychosis in Ultra-High Risk 
      (UHR) individuals. We aimed to: 1) validate the Italian version of the Global 
      Functioning: Social (GF: S) and Global Functioning: Role (GF: S) scales; 2) 
      evaluate their association with UHR criteria. Participants were 12-21-years-old 
      (age, mean=15.2, standard deviation=2.1, male/female ratio=117/120) nonpsychotic 
      help-seekers, meeting (N=39) or not (N=198) UHR criteria. Inter-rater reliability 
      was excellent for both scales, which also showed good to excellent concurrent 
      validity, as measured by correlation with Global Assessment of Functioning (GAF) 
      scores. Furthermore, GF:S and GF: R were able to discriminate between UHRs and 
      non-UHRs, with UHRs having lower current scores. After adjusting for current GAF 
      scores, only current GF:S scores independently differentiated UHR from non-UHR 
      (OR=1.33, 95%CI: 1.02-1.75, p=0.033). Finally, UHR participants showed a steeper 
      decrease from highest GF:S and GF: R scores in the past year to their respective 
      current scores, but not from highest past year GAF scores to current scores. 
      GF:S/GS: R scores were not affected by age or sex. GF:S/GF: R are useful 
      functional level and outcome measures, having the advantage over the GAF to not 
      confound functioning with symptom severity. Additionally, the GF:S may be helpful 
      in identifying UHR individuals.
CI  - Copyright (c) 2017. Published by Elsevier B.V.
FAU - Lo Cascio, Nella
AU  - Lo Cascio N
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy; Department of Neurosciences and 
      Neurorehabilitation, Bambino Gesu Children's Hospital, Rome, Italy. Electronic 
      address: nellalocascio@gmail.com.
FAU - Curto, Martina
AU  - Curto M
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy.
FAU - Pasqualetti, Patrizio
AU  - Pasqualetti P
AD  - Department of Neurosciences and Neurorehabilitation, Bambino Gesu Children's 
      Hospital, Rome, Italy; Service of Medical Statistics and Information Technology, 
      Fatebenefratelli Foundation for Health Research and Education, AFaR Division, 
      Rome, Italy.
FAU - Lindau, Juliana Fortes
AU  - Lindau JF
AD  - Neurosciences, Mental Health and Sensory Functions (NESMOS) Department, School of 
      Medicine and Psychology, Sapienza University - Rome, Acute Psychiatric Care Unit, 
      Sant'Andrea Hospital, Rome, Italy.
FAU - Girardi, Nicoletta
AU  - Girardi N
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy.
FAU - Saba, Riccardo
AU  - Saba R
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy.
FAU - Brandizzi, Martina
AU  - Brandizzi M
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy.
FAU - Monducci, Elena
AU  - Monducci E
AD  - Department of Neurosciences and Neurorehabilitation, Bambino Gesu Children's 
      Hospital, Rome, Italy.
FAU - Masillo, Alice
AU  - Masillo A
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy.
FAU - Colafrancesco, Giada
AU  - Colafrancesco G
AD  - Pediatrics and Pediatric Neuropsychiatry Department, School of Medicine and 
      Dentistry, Sapienza University, Rome, Italy.
FAU - Solfanelli, Andrea
AU  - Solfanelli A
AD  - Neurosciences, Mental Health and Sensory Functions (NESMOS) Department, School of 
      Medicine and Psychology, Sapienza University - Rome, Acute Psychiatric Care Unit, 
      Sant'Andrea Hospital, Rome, Italy.
FAU - De Crescenzo, Franco
AU  - De Crescenzo F
AD  - Department of Neurosciences and Neurorehabilitation, Bambino Gesu Children's 
      Hospital, Rome, Italy; Institute of Psychiatry and Psychology, Catholic 
      University Medical School, Agostino Gemelli Hospital, Rome, Italy.
FAU - Kotzalidis, Georgios D
AU  - Kotzalidis GD
AD  - Neurosciences, Mental Health and Sensory Functions (NESMOS) Department, School of 
      Medicine and Psychology, Sapienza University - Rome, Acute Psychiatric Care Unit, 
      Sant'Andrea Hospital, Rome, Italy.
FAU - Dario, Claudia
AU  - Dario C
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy.
FAU - Ferrara, Mauro
AU  - Ferrara M
AD  - Pediatrics and Pediatric Neuropsychiatry Department, School of Medicine and 
      Dentistry, Sapienza University, Rome, Italy.
FAU - Vicari, Stefano
AU  - Vicari S
AD  - Department of Neurosciences and Neurorehabilitation, Bambino Gesu Children's 
      Hospital, Rome, Italy.
FAU - Girardi, Paolo
AU  - Girardi P
AD  - Neurosciences, Mental Health and Sensory Functions (NESMOS) Department, School of 
      Medicine and Psychology, Sapienza University - Rome, Acute Psychiatric Care Unit, 
      Sant'Andrea Hospital, Rome, Italy.
FAU - Auther, Andrea M
AU  - Auther AM
AD  - The Zucker Hillside Hospital Department of Psychiatry, Northwell Health, Glen 
      Oaks, NY, USA; Hofstra Northwell School of Medicine, Hofstra University, 
      Hempstead, NY, USA.
FAU - Cornblatt, Barbara A
AU  - Cornblatt BA
AD  - The Zucker Hillside Hospital Department of Psychiatry, Northwell Health, Glen 
      Oaks, NY, USA; Hofstra Northwell School of Medicine, Hofstra University, 
      Hempstead, NY, USA; The Feinstein Institute for Medical Research, Manhasset, NY, 
      USA.
FAU - Correll, Christoph U
AU  - Correll CU
AD  - The Zucker Hillside Hospital Department of Psychiatry, Northwell Health, Glen 
      Oaks, NY, USA; Hofstra Northwell School of Medicine, Hofstra University, 
      Hempstead, NY, USA; The Feinstein Institute for Medical Research, Manhasset, NY, 
      USA.
FAU - Fiori Nastro, Paolo
AU  - Fiori Nastro P
AD  - Department of Neurology and Psychiatry, School of Medicine and Dentistry, 
      Sapienza University, Rome, Italy.
LA  - eng
GR  - P30 MH090590/MH/NIMH NIH HHS/United States
PT  - Journal Article
PT  - Validation Study
DEP - 20170406
PL  - Ireland
TA  - Psychiatry Res
JT  - Psychiatry research
JID - 7911385
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Italy
MH  - Language
MH  - Male
MH  - Mental Disorders/*diagnosis/psychology
MH  - Psychiatric Status Rating Scales/*standards
MH  - Psychotic Disorders/*diagnosis/psychology
MH  - Reproducibility of Results
MH  - Risk Assessment
MH  - *Social Adjustment
MH  - Translations
MH  - Young Adult
OTO - NOTNLM
OT  - Adolescents
OT  - Psychosis
OT  - Rating scales
OT  - Reliability
OT  - Social functioning
OT  - Validation
EDAT- 2017/04/17 06:00
MHDA- 2018/01/20 06:00
CRDT- 2017/04/17 06:00
PHST- 2016/09/05 00:00 [received]
PHST- 2017/02/26 00:00 [revised]
PHST- 2017/04/02 00:00 [accepted]
PHST- 2017/04/17 06:00 [pubmed]
PHST- 2018/01/20 06:00 [medline]
PHST- 2017/04/17 06:00 [entrez]
AID - S0165-1781(16)31520-7 [pii]
AID - 10.1016/j.psychres.2017.04.008 [doi]
PST - ppublish
SO  - Psychiatry Res. 2017 Jul;253:296-302. doi: 10.1016/j.psychres.2017.04.008. Epub 
      2017 Apr 6.