PMID- 28414982
OWN - NLM
STAT- MEDLINE
DCOM- 20180402
LR  - 20181202
IS  - 1557-8615 (Electronic)
IS  - 0883-9441 (Linking)
VI  - 40
DP  - 2017 Aug
TI  - Relation of positive fluid balance to the severity of renal impairment and 
      recovery among ST elevation myocardial infarction complicated by cardiogenic 
      shock.
PG  - 184-188
LID - S0883-9441(17)30095-3 [pii]
LID - 10.1016/j.jcrc.2017.04.011 [doi]
AB  - PURPOSE: We analyzed the relationship between a positive fluid balance and its 
      persistence over time on acute kidney injury (AKI) development, severity and 
      resolution among ST elevation myocardial infarction (STEMI) patients complicated 
      by cardiogenic shock. METHODS: We retrospectively studied the cumulative fluid 
      balance intake and output at 96h following hospital admission in 84 consecutive 
      adult patients with STEMI complicated by cardiogenic shock. The cohort was 
      stratified into two groups, based on the presence or absence of positive fluid 
      balance on day 4. Patients' records were assessed for the development of AKI, AKI 
      severity and recovery. RESULTS: Patients having positive fluid balance were more 
      likely to develop a more severe AKI stage (52% vs. 13%; p<0.001), were less 
      likely to have recovery of their renal function (29% vs. 75%, p=0.001), and 
      demonstrated positive correlation between the amount of fluid accumulated and the 
      rise in serum creatinine (R=0.42, p=0.004). For every 1l increase in positive 
      fluid balance, the adjusted possibility for recovery of renal function decreased 
      by 21% (OR=0.796, 95% CI 0.67-0.93; p=0.006). CONCLUSIONS: A positive fluid 
      balance was strongly associated with higher stage AKI and lower rate of AKI 
      recovery in STEMI complicated by cardiogenic shock.
CI  - Copyright (c) 2017 Elsevier Inc. All rights reserved.
FAU - Margolis, Gilad
AU  - Margolis G
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. Electronic 
      address: gilad.margolis@gmail.com.
FAU - Kofman, Natalia
AU  - Kofman N
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
FAU - Gal-Oz, Amir
AU  - Gal-Oz A
AD  - Intensive Care Unit, Tel-Aviv Sourasky Medical Center Affiliated to the Sackler 
      Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
FAU - Arbel, Yaron
AU  - Arbel Y
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
FAU - Khoury, Shafik
AU  - Khoury S
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
FAU - Keren, Gad
AU  - Keren G
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
FAU - Shacham, Yacov
AU  - Shacham Y
AD  - Department of Cardiology, Tel-Aviv Sourasky Medical Center Affiliated to the 
      Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20170407
PL  - United States
TA  - J Crit Care
JT  - Journal of critical care
JID - 8610642
SB  - IM
MH  - Acute Kidney Injury/*etiology/physiopathology
MH  - Aged
MH  - Cohort Studies
MH  - Female
MH  - Hospitalization/statistics & numerical data
MH  - Humans
MH  - Retrospective Studies
MH  - ST Elevation Myocardial Infarction/*complications/physiopathology
MH  - Shock, Cardiogenic/*complications/physiopathology
MH  - Water-Electrolyte Balance/physiology
MH  - Water-Electrolyte Imbalance/*complications/physiopathology
OTO - NOTNLM
OT  - Acute kidney injury
OT  - Fluid balance
OT  - Myocardial infarction
OT  - Shock
EDAT- 2017/04/18 06:00
MHDA- 2018/04/03 06:00
CRDT- 2017/04/18 06:00
PHST- 2017/01/22 00:00 [received]
PHST- 2017/04/06 00:00 [accepted]
PHST- 2017/04/18 06:00 [pubmed]
PHST- 2018/04/03 06:00 [medline]
PHST- 2017/04/18 06:00 [entrez]
AID - S0883-9441(17)30095-3 [pii]
AID - 10.1016/j.jcrc.2017.04.011 [doi]
PST - ppublish
SO  - J Crit Care. 2017 Aug;40:184-188. doi: 10.1016/j.jcrc.2017.04.011. Epub 2017 Apr 
      7.