PMID- 28419272
OWN - NLM
STAT- MEDLINE
DCOM- 20170922
LR  - 20190121
IS  - 1938-2928 (Electronic)
IS  - 0022-2585 (Linking)
VI  - 54
IP  - 5
DP  - 2017 Sep 1
TI  - Insecticidal and Behavioral Avoidance Responses of Anopheles minimus and Culex 
      quinquefasciatus (Diptera: Culicidae) to Three Synthetic Repellents.
PG  - 1312-1322
LID - 10.1093/jme/tjx081 [doi]
AB  - Escape responses, knockdown (KD), and toxicity of laboratory strains of Anopheles 
      minimus Theobald and Culex quinquefasciatus Say to three synthetic mosquito 
      repellents, DEET (N, N-diethyl-3-methylbenzamide), IR3535, or picaridin, at 5% 
      v/v concentrations, were evaluated using repellent-treated papers in standard WHO 
      tube assays and an excito-repellency (ER) test chamber system. The tube assays 
      recorded knockdown effects of each repellent immediately after 30-min exposure 
      and the final morality following a 24-h holding period. DEET showed 100% KD at 
      30 min and complete toxicity at 24 h against both species. Both actions were 
      either minimal or absent for IR3535 and picaridin, respectively. Culex 
      quinquefasciatus showed significantly greater escape with DEET compared with the 
      other compounds in both contact irritancy (excitation) and noncontact spatial 
      repellency trials. Anopheles minimus showed much more pronounced irritancy and 
      repellency flight escape to IR3535 than picaridin. DEET was the most active 
      irritant and repellent compound against Cx. quinquefasciatus. When adjusting 
      contact test responses based on paired noncontact repellency assays, DEET and 
      IR3535 showed much stronger spatial repellent properties than irritancy with An. 
      minimus. Picaridin performed poorly as an irritant or repellent against both 
      species. We conclude that DEET, followed by IR3535, act as strong spatial 
      repellents at 5% concentration. DEET also performs as a strong toxicant. Our 
      findings show that different mosquitoes can respond contrastingly to repellents, 
      thus the importance to test a wider range of species and populations to assess 
      the full range of chemical action.
CI  - (c) The Authors 2017. Published by Oxford University Press on behalf of 
      Entomological Society of America. All rights reserved. For Permissions, please 
      email: journals.permissions@oup.com.
FAU - Boonyuan, Wasana
AU  - Boonyuan W
AD  - Department of Entomology, Faculty of Agriculture, Kasetsart University, Bangkok 
      10900, Thailand.
AD  - Center for Advanced Studies for Agriculture and Food, Kasetsart University 
      Institute for Advanced Studies, Kasetsart University, Bangkok 10900, Thailand.
FAU - Sathantriphop, Sunaiyana
AU  - Sathantriphop S
AD  - Ministry of Public Health, National Institute of Health, Nonthaburi 11000, 
      Thailand.
FAU - Tainchum, Krajana
AU  - Tainchum K
AD  - Center for Advanced Studies for Agriculture and Food, Kasetsart University 
      Institute for Advanced Studies, Kasetsart University, Bangkok 10900, Thailand.
AD  - Department of Pest Management, Faculty of Natural Resources, Prince of Songkla 
      University, Bangkok 90110, Thailand.
FAU - Muenworn, Vithee
AU  - Muenworn V
AD  - Department of Plant Science and Agricultural Resources, Faculty of Agriculture, 
      Khon Kaen University, Khon Kaen 40002, Thailand.
FAU - Prabaripai, Atchariya
AU  - Prabaripai A
AD  - Division of Computer and Statistics, Faculty of Liberal Art and Science, 
      Kasetsart University, Kamphaensean, Nakhon Pathom 73140, Thailand.
FAU - Bangs, Michael J
AU  - Bangs MJ
AD  - Department of Entomology, Faculty of Agriculture, Kasetsart University, Bangkok 
      10900, Thailand.
AD  - Public Health & Malaria Control Department, PT Freeport Indonesia, International 
      SOS, Jl. Kertajasa Kuala Kencana, Papua 99920, Indonesia.
FAU - Chareonviriyaphap, Theeraphap
AU  - Chareonviriyaphap T
AD  - Department of Entomology, Faculty of Agriculture, Kasetsart University, Bangkok 
      10900, Thailand.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Med Entomol
JT  - Journal of medical entomology
JID - 0375400
RN  - 0 (Insect Repellents)
RN  - 0 (Piperidines)
RN  - 0 (Propionates)
RN  - 134-62-3 (DEET)
RN  - 65GQA237EH (ethyl-3-(N-n-butyl-N-acetyl)aminopropionate)
RN  - N51GQX0837 (picaridin)
SB  - IM
MH  - Animals
MH  - *Anopheles
MH  - *Culex
MH  - *DEET
MH  - Female
MH  - *Insect Repellents
MH  - *Piperidines
MH  - *Propionates
OTO - NOTNLM
OT  - DEET
OT  - IR3535
OT  - excito-repellency
OT  - mortality
OT  - picaridin
EDAT- 2017/04/19 06:00
MHDA- 2017/09/25 06:00
CRDT- 2017/04/19 06:00
PHST- 2016/10/14 00:00 [received]
PHST- 2017/04/19 06:00 [pubmed]
PHST- 2017/09/25 06:00 [medline]
PHST- 2017/04/19 06:00 [entrez]
AID - 3737816 [pii]
AID - 10.1093/jme/tjx081 [doi]
PST - ppublish
SO  - J Med Entomol. 2017 Sep 1;54(5):1312-1322. doi: 10.1093/jme/tjx081.