PMID- 28420896 OWN - NLM STAT- MEDLINE DCOM- 20171016 LR - 20220331 IS - 0386-300X (Print) IS - 0386-300X (Linking) VI - 71 IP - 2 DP - 2017 Apr TI - Toe Pinch Force in Male Type 2 Diabetes Mellitus Patients. PG - 143-149 LID - 10.18926/AMO/54983 [doi] AB - We compared the toe pinch force in men with and without type 2 diabetes mellitus (T2DM). Sixty-eight male T2DM patients and 35 apparently healthy men matched for age, sex, and body mass index (BMI) were enrolled in this cross-sectional study. We compared the toe pinch force between the subjects with and without T2DM, and we evaluated the effect of diabetic polyneuropathy on toe pinch force in the patients. The toe pinch force of the T2DM patients was significantly lower than that of the subjects without diabetes (3.12+/-1.22 kg vs. 4.40+/-1.19 kg, p<0.001). Multiple regression analysis showed that T2DM was a determinant of reduced toe pinch force. In addition, the toe pinch force of patients with diabetic polyneuropathy was significantly lower than that of patients without diabetic polyneuropathy (2.31+/-0.93 kg vs. 3.70+/-1.07 kg, p<0.001). Multiple regression analysis showed that diabetic polyneuropathy was a determinant of the toe pinch force in men with T2DM, even after adjusting for age, BMI, HbA1c, and duration of diabetes. Reduced toe pinch force is a fundamental feature of motor dysfunction in men with T2DM, and diabetic polyneuropathy might be associated with toe pinch force in these patients. FAU - Kataoka, Hiroaki AU - Kataoka H AD - Rehabilitation Center, KKR Takamatsu Hospital, Kagawa 760-0018, Japan.h.kataoka59@gmail.com. FAU - Miyatake, Nobuyuki AU - Miyatake N FAU - Kitayama, Naomi AU - Kitayama N FAU - Murao, Satoshi AU - Murao S FAU - Tanaka, Satoshi AU - Tanaka S LA - eng PT - Journal Article PL - Japan TA - Acta Med Okayama JT - Acta medica Okayama JID - 0417611 SB - IM MH - Aged MH - Analysis of Variance MH - Case-Control Studies MH - Cross-Sectional Studies MH - Diabetes Mellitus, Type 2/*physiopathology MH - Diabetic Nephropathies/*physiopathology MH - Diabetic Neuropathies/etiology MH - Humans MH - Male MH - Middle Aged MH - *Muscle Strength MH - Statistics, Nonparametric MH - Toes/*physiopathology OTO - NOTNLM OT - diabetic polyneuropathy OT - toe pinch force OT - type 2 diabetes mellitus COIS- No potential conflict of interest relevant to this article was reported. EDAT- 2017/04/20 06:00 MHDA- 2017/10/17 06:00 CRDT- 2017/04/20 06:00 PHST- 2017/04/20 06:00 [entrez] PHST- 2017/04/20 06:00 [pubmed] PHST- 2017/10/17 06:00 [medline] AID - 10.18926/AMO/54983 [doi] PST - ppublish SO - Acta Med Okayama. 2017 Apr;71(2):143-149. doi: 10.18926/AMO/54983.