PMID- 28424243
OWN - NLM
STAT- MEDLINE
DCOM- 20171003
LR  - 20171010
IS  - 2154-1663 (Print)
IS  - 2154-1671 (Linking)
VI  - 7
IP  - 5
DP  - 2017 May
TI  - Nutrition and High-Flow Nasal Cannula Respiratory Support in Children With 
      Bronchiolitis.
PG  - 256-262
LID - 10.1542/hpeds.2016-0194 [doi]
AB  - OBJECTIVES: No guidelines are available regarding initiation of enteral nutrition 
      in children with bronchiolitis on high-flow nasal cannula (HFNC) support. We 
      hypothesized that the incidence of feeding-related adverse events (AEs) would not 
      be associated with HFNC support. METHODS: This retrospective study included 
      children </=24 months old with bronchiolitis receiving HFNC in a PICU from 
      September 2013 through April 2014. Data included demographics, respiratory 
      support during feeding, and feeding-related AEs. Feeding-related AEs were 
      extracted from nursing documentation and defined as respiratory distress or 
      emesis. Feed route and maximum HFNC delivery were recorded in 8-hour shifts (6 
      am-2 pm, 2 pm-10 pm, and 10 pm-6 am). RESULTS: 70 children were included, with a 
      median age of 5 (interquartile range [IQR] 2-10) months. HFNC delivery at feed 
      initiation varied widely, and AEs related to feeding occurred rarely. Children 
      were fed in 501 of 794 (63%) of nursing shifts, with AEs documented in only 29 of 
      501 (5.8%) of those shifts. The incidence of AEs at varying levels of respiratory 
      support did not differ (P = .092). Children in the "early feeding" (fed within 
      first 2 shifts) group (n = 22) had a shorter PICU length of stay (2.2 days [IQR 
      1.4-3.9] vs 3.2 [IQR 2.5-5.3], P = .006) and shorter duration of HFNC use (26.0 
      hours [IQR 15.8-57.0] vs 53.5 [IQR 37.0-84.8], P = .002), compared with children 
      in the "late feeding" group (n = 48). CONCLUSIONS: In this small, 
      single-institution patient cohort, feeding-related AEs were rare and not related 
      to the delivered level of respiratory support.
CI  - Copyright (c) 2017 by the American Academy of Pediatrics.
FAU - Slain, Katherine N
AU  - Slain KN
AD  - Rainbow Babies & Children's Hospital, Cleveland, Ohio; and 
      katherine.slain@uhhospitals.org.
FAU - Martinez-Schlurmann, Natalia
AU  - Martinez-Schlurmann N
AD  - Children's Hospital of Georgia, Augusta, Georgia.
FAU - Shein, Steven L
AU  - Shein SL
AD  - Rainbow Babies & Children's Hospital, Cleveland, Ohio; and.
FAU - Stormorken, Anne
AU  - Stormorken A
AD  - Rainbow Babies & Children's Hospital, Cleveland, Ohio; and.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Hosp Pediatr
JT  - Hospital pediatrics
JID - 101585349
SB  - IM
CIN - Hosp Pediatr. 2017 May;7(5):297-299. PMID: 28424244
MH  - Bronchiolitis/*therapy
MH  - *Enteral Nutrition
MH  - Female
MH  - Humans
MH  - Infant
MH  - Infant, Newborn
MH  - Intensive Care Units, Pediatric
MH  - Length of Stay/statistics & numerical data
MH  - Male
MH  - *Oxygen Inhalation Therapy
MH  - Respiratory Insufficiency/etiology
MH  - Retrospective Studies
MH  - Vomiting/etiology
COIS- POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential 
      conflicts of interest to disclose.
EDAT- 2017/04/21 06:00
MHDA- 2017/10/04 06:00
CRDT- 2017/04/21 06:00
PHST- 2017/04/21 06:00 [pubmed]
PHST- 2017/10/04 06:00 [medline]
PHST- 2017/04/21 06:00 [entrez]
AID - hpeds.2016-0194 [pii]
AID - 10.1542/hpeds.2016-0194 [doi]
PST - ppublish
SO  - Hosp Pediatr. 2017 May;7(5):256-262. doi: 10.1542/hpeds.2016-0194.