PMID- 28425767 OWN - NLM STAT- MEDLINE DCOM- 20170905 LR - 20170906 IS - 1651-2006 (Electronic) IS - 1401-7431 (Linking) VI - 51 IP - 4 DP - 2017 Aug TI - Chronic total coronary occlusion: treatment results. PG - 197-201 LID - 10.1080/14017431.2017.1319575 [doi] AB - OBJECTIVES: To describe the clinical and procedural coronary chronic total occlusion (CTO) treatment results in a Nordic PCI centre during the implementation of a CTO treatment program. DESIGN: In a retrospective registry study, we assessed; (1) indication for the procedure, (2) Canadian Cardiovascular Society angina pectoris score (CCS)/New York Heart Association (NYHA) heart failure score, (3) lesion complexity and (4) adverse events during hospital stay and three months following the index procedure. RESULTS: The study cohort included 503 patients (594 lesions). From 2010 to 2013 96% of procedures were performed with antegrade wire-escalation technique and 4% performed using retrograde techniques, from 2013-2016 the corresponding numbers were 83% and 17.0%. The procedural success rate was 69%, increasing from 64% before to 72% (p = .06) after routinely using the retrograde approach. No individual patient characteristic, lesion variable or score was strongly associated with procedural success or failure. There were 4% serious procedure related complications. In patients with PCI of a CTO lesion only, 87% were in CCS or NYHA functional class >/=2 before the index procedure vs. 22% at follow-up. CONCLUSIONS: Routine use of retrograde techniques tended to increase the procedural success rate. Clinical results after three months were acceptable, but the complication rate was higher than for non-CTO PCI. Individual patient and lesion characteristics had a low predictability for procedural success. Therefore, clinical symptoms, objective signs of myocardial ischemia and procedural risk should be focus points in coronary chronic total occlusion treatment strategies. FAU - Kirk Christensen, Martin AU - Kirk Christensen M AUID- ORCID: 0000-0003-4136-409X AD - a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark. FAU - Freeman, Phillip Fischer AU - Freeman PF AD - a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark. FAU - Rasmussen, Jeppe Groendal AU - Rasmussen JG AD - a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark. FAU - Villadsen, Anton Boel AU - Villadsen AB AD - a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark. FAU - Raungaard, Bent AU - Raungaard B AD - a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark. FAU - Eggert Jensen, Svend AU - Eggert Jensen S AD - a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark. FAU - Thuesen, Leif AU - Thuesen L AD - a Department of Cardiology , Aalborg University Hospital , Aalborg , Denmark. LA - eng PT - Comparative Study PT - Journal Article DEP - 20170420 PL - England TA - Scand Cardiovasc J JT - Scandinavian cardiovascular journal : SCJ JID - 9708377 SB - IM MH - Aged MH - Chronic Disease MH - Coronary Occlusion/diagnostic imaging/*therapy MH - Denmark MH - Female MH - Humans MH - Male MH - Middle Aged MH - Percutaneous Coronary Intervention/adverse effects/*methods MH - Registries MH - Retrospective Studies MH - Time Factors MH - Treatment Outcome OTO - NOTNLM OT - Chronic total occlusion OT - angina OT - coronary OT - cto OT - pci OT - percutaneus coronary intervention EDAT- 2017/04/21 06:00 MHDA- 2017/09/07 06:00 CRDT- 2017/04/21 06:00 PHST- 2017/04/21 06:00 [pubmed] PHST- 2017/09/07 06:00 [medline] PHST- 2017/04/21 06:00 [entrez] AID - 10.1080/14017431.2017.1319575 [doi] PST - ppublish SO - Scand Cardiovasc J. 2017 Aug;51(4):197-201. doi: 10.1080/14017431.2017.1319575. Epub 2017 Apr 20.