PMID- 28428968 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240325 IS - 2322-4436 (Print) IS - 2322-3219 (Electronic) IS - 2322-3219 (Linking) VI - 6 IP - 1 DP - 2017 Spring TI - Allergic Conjunctivitis in Patients with Respiratory Allergic Symptoms; a Retrospective Study in Greece. PG - 3-9 AB - Here, we report on the prevalence of allergic conjunctivitis and positive skin prick test (SPT) results in relation to respiratory allergic conditions among patients with symptoms of allergies at a respiratory outpatient clinic. A questionnaire survey of symptoms (i.e., asthma-like, rhinitis, and conjunctivitis symptoms) involving 1522 patients was carried out. The responses of 1242 patients indicated that they had allergic conjunctivitis, asthma, rhinitis, or a combination of these conditions, and 869 of these patients underwent SPTs that assessed responses to 40 allergens. Allergic conjunctivitis was found to be very common (40%, 497 out of 1242 patients) among those with symptoms of allergies. Conjunctivitis was slightly more common among women, while rhinitis was more common among men. Patients with both conjunctivitis and rhinitis were more likely to undergo SPTs, and they had a higher rate of positive SPTs. The coexistence of two or more comorbidities increased the risk of having an immunoglobulin E (IgE)-mediated allergy (based on the SPT results) compared to having each of the conditions alone. In conclusion, allergic conjunctivitis can occur either alone or with asthma and/or rhinitis. It is not always accompanied by rhinitis, but the coexistence of these conditions was the strongest indicator of IgE-mediated allergies. FAU - Michailopoulos, Pavlos AU - Michailopoulos P AD - Pulmonary Department, 424 General Military Hospital of Thessaloniki, Greece. AD - Laboratory of Experimental Ophthalmology, Aristotle University of Thessaloniki, Greece. FAU - Almaliotis, Diamantis AU - Almaliotis D AD - Laboratory of Experimental Ophthalmology, Aristotle University of Thessaloniki, Greece. FAU - Georgiadou, Irini AU - Georgiadou I AD - Laboratory of Experimental Ophthalmology, Aristotle University of Thessaloniki, Greece. FAU - Papakosta, Despina AU - Papakosta D AD - Pulmonary Department of G. Papanicolaou Hospital, Aristotle University of Thessaloniki, Greece. FAU - Gougoulias, Kyriakos AU - Gougoulias K AD - Laboratory of Experimental Ophthalmology, Aristotle University of Thessaloniki, Greece. FAU - Giouleka, Paschalina AU - Giouleka P AD - Pulmonary Department of G. Papanicolaou Hospital, Aristotle University of Thessaloniki, Greece. FAU - Gioulekas, Dimitrios AU - Gioulekas D AD - Pulmonary Department of G. Papanicolaou Hospital, Aristotle University of Thessaloniki, Greece. FAU - Siempis, Thomas AU - Siempis T AD - Laboratory of Experimental Ophthalmology, Aristotle University of Thessaloniki, Greece. FAU - Karampatakis, Vasileios AU - Karampatakis V AD - Laboratory of Experimental Ophthalmology, Aristotle University of Thessaloniki, Greece. LA - eng PT - Journal Article PL - United States TA - Med Hypothesis Discov Innov Ophthalmol JT - Medical hypothesis, discovery & innovation ophthalmology journal JID - 101611331 PMC - PMC5392226 OTO - NOTNLM OT - Allergic Comorbidities OT - Allergic Conjunctivitis OT - Allergic Rhinitis OT - Asthma OT - Skin Prick Tests COIS- None declared. All the aforementioned authors met the International Committee of Medical Journal Editors (ICMJE) criteria for authorship for this manuscript, take responsibility for the integrity of the work as a whole, and have provided approval for the revised manuscript to be published. EDAT- 2017/04/22 06:00 MHDA- 2017/04/22 06:01 PMCR- 2017/03/01 CRDT- 2017/04/22 06:00 PHST- 2017/04/22 06:00 [entrez] PHST- 2017/04/22 06:00 [pubmed] PHST- 2017/04/22 06:01 [medline] PHST- 2017/03/01 00:00 [pmc-release] AID - mehdiophth-6-003 [pii] PST - ppublish SO - Med Hypothesis Discov Innov Ophthalmol. 2017 Spring;6(1):3-9.