PMID- 28429201
OWN - NLM
STAT- MEDLINE
DCOM- 20171214
LR  - 20181202
IS  - 1534-312X (Electronic)
IS  - 1522-8037 (Linking)
VI  - 19
IP  - 6
DP  - 2017 Jun
TI  - How to Approach Lymphocytic Esophagitis.
PG  - 24
LID - 10.1007/s11894-017-0564-y [doi]
AB  - PURPOSE OF REVIEW: Lymphocytic esophagitis (LE) is an unusual esophageal 
      condition defined by an increased number of lymphocytes in the esophageal 
      epithelium. With few published studies of LE available, it is unclear whether LE 
      is a truly distinct clinical entity or a histological manifestation of other 
      known gastrointestinal disorders. This review summarizes recent studies of 
      lymphocytic esophagitis. RECENT FINDINGS: Studies have suggested that LE may be 
      related to eosinophilic esophagitis (EoE) or a manifestation of gastroesophageal 
      reflux disease (GERD). There is an association between LE and Crohn's disease in 
      children, but not in adults. Patients with LE frequently report symptoms of 
      dysphagia and GERD. Treatment options for LE are limited and involve symptom 
      management similar to treatment of EoE or GERD, including proton pump inhibitors 
      (PPI), swallowed topical steroids, and endoscopic dilation. With no formal 
      definition and a variety of clinical presentations and endoscopic findings, 
      diagnosis and management of symptomatic LE patients is challenging for 
      clinicians.
FAU - Nguyen, Anh D
AU  - Nguyen AD
AD  - Division of Gastroenterology and Hepatology, Department of Medicine, University 
      of Texas Southwestern Medical Center, Dallas, TX, 75231, USA.
FAU - Dunbar, Kerry B
AU  - Dunbar KB
AD  - Esophageal Diseases Center, Division of Gastroenterology and Hepatology, 
      Department of Medicine, Dallas VA Medical Center and the University of Texas 
      Southwestern Medical Center, GI Lab-CA 111-B1, Dallas VAMC, 4500 South Lancaster 
      Road, Dallas, TX, 75231, USA. Kerry.Dunbar@utsouthwestern.edu.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Gastroenterol Rep
JT  - Current gastroenterology reports
JID - 100888896
RN  - 0 (Proton Pump Inhibitors)
SB  - IM
MH  - Age Factors
MH  - Crohn Disease/complications
MH  - Deglutition Disorders/etiology
MH  - Dilatation
MH  - Eosinophilic Esophagitis/pathology
MH  - *Esophagitis/etiology/pathology
MH  - Gastroesophageal Reflux/complications
MH  - Humans
MH  - *Lymphocytosis/etiology/pathology/therapy
MH  - Proton Pump Inhibitors/therapeutic use
OTO - NOTNLM
OT  - Dysphagia
OT  - Gastroesophageal reflux disease (GERD)
OT  - Lymphocytic esophagitis
OT  - Lymphocytic oesophagitis
EDAT- 2017/04/22 06:00
MHDA- 2017/12/15 06:00
CRDT- 2017/04/22 06:00
PHST- 2017/04/22 06:00 [entrez]
PHST- 2017/04/22 06:00 [pubmed]
PHST- 2017/12/15 06:00 [medline]
AID - 10.1007/s11894-017-0564-y [pii]
AID - 10.1007/s11894-017-0564-y [doi]
PST - ppublish
SO  - Curr Gastroenterol Rep. 2017 Jun;19(6):24. doi: 10.1007/s11894-017-0564-y.