PMID- 28431009
OWN - NLM
STAT- MEDLINE
DCOM- 20190208
LR  - 20190215
IS  - 1532-2092 (Electronic)
IS  - 1099-5129 (Linking)
VI  - 20
IP  - 5
DP  - 2018 May 1
TI  - Artefact-free late gadolinium enhancement imaging in patients with implanted 
      cardiac devices using a modified broadband sequence: current strategies and 
      results from a real-world patient cohort.
PG  - 801-807
LID - 10.1093/europace/eux016 [doi]
AB  - AIMS: Cardiac magnetic resonance (CMR) imaging in patients with implanted cardiac 
      devices is often limited by device-related imaging artefacts. Limitations can 
      potentially be overcome by employing a broadband late gadolinium enhancement 
      (LGE)-CMR imaging technique. The purpose of this study was to investigate the 
      relationship between implanted cardiac devices and the optimal frequency offset 
      on broadband LGE-CMR imaging to increase the artefact-free visibility of 
      myocardial segments. METHODS AND RESULTS: A phantom study was performed to 
      characterize magnetic field disturbances related to 15 different cardiac devices. 
      This was complemented by B0 and B1+ imaging of three different device types in 
      four healthy volunteers. Findings were validated in 28 patients with an 
      indication for arrhythmogenic substrate characterization before catheter 
      ablation. In the phantom study, the placement of a PM, implantable 
      cardioverter-defibrillator (ICD) or CRT-D generator led to a significant 
      impairment of the radiofrequency field. B0 mapping in phantom and volunteers 
      showed the highest off-resonance maximum with CRT-D systems with the maximum 
      off-resonance significantly decreasing for ICD or PM systems, respectively. In 
      all patients, with conventional LGE imaging 73.1% (61.5-92.3%) of LV segments 
      were free of device-related artefacts, while with the broadband LGE technique, a 
      significant increase of artefact-free segments was achieved [96.4% (85.7-100%); 
      P = 0.00008]. CONCLUSION: Using a modified broadband sequence for LGE imaging 
      significantly increased the number of artefact-free myocardial segments thereby 
      leading to improved diagnostic value of the CMR exam. Since the occurrence and 
      extent of hyperintensity artefacts are closely related to the individual device, 
      more studies are warranted to evaluate if the results can be extrapolated to 
      other devices and manufacturers.
FAU - Hilbert, Sebastian
AU  - Hilbert S
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Weber, Alexander
AU  - Weber A
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Nehrke, Kay
AU  - Nehrke K
AD  - Philips Research Laboratories, Hamburg, Germany.
FAU - Bornert, Peter
AU  - Bornert P
AD  - Philips Research Laboratories, Hamburg, Germany.
FAU - Schnackenburg, Bernhard
AU  - Schnackenburg B
AD  - Philips Research Laboratories, Hamburg, Germany.
FAU - Oebel, Sabrina
AU  - Oebel S
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Spampinato, Ricardo
AU  - Spampinato R
AD  - Department of Cardiac Surgery, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Rogge, Cathleen
AU  - Rogge C
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Richter, Sergio
AU  - Richter S
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Hindricks, Gerhard
AU  - Hindricks G
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Paetsch, Ingo
AU  - Paetsch I
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
FAU - Jahnke, Cosima
AU  - Jahnke C
AD  - Department of Electrophysiology, HELIOS Heart Center Leipzig, Leipzig, Germany.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Europace
JT  - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal 
      of the working groups on cardiac pacing, arrhythmias, and cardiac cellular 
      electrophysiology of the European Society of Cardiology
JID - 100883649
RN  - 0 (Contrast Media)
RN  - AU0V1LM3JT (Gadolinium)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Arrhythmias, Cardiac/etiology/*prevention & control
MH  - Artifacts
MH  - Contrast Media/therapeutic use
MH  - *Defibrillators, Implantable
MH  - Female
MH  - Gadolinium/*therapeutic use
MH  - Humans
MH  - *Image Enhancement/instrumentation/methods
MH  - Kaplan-Meier Estimate
MH  - *Magnetic Resonance Imaging/instrumentation/methods
MH  - Male
MH  - Middle Aged
MH  - Phantoms, Imaging
MH  - Reproducibility of Results
EDAT- 2017/04/22 06:00
MHDA- 2019/02/09 06:00
CRDT- 2017/04/22 06:00
PHST- 2016/08/07 00:00 [received]
PHST- 2017/01/17 00:00 [accepted]
PHST- 2017/04/22 06:00 [pubmed]
PHST- 2019/02/09 06:00 [medline]
PHST- 2017/04/22 06:00 [entrez]
AID - 3739747 [pii]
AID - 10.1093/europace/eux016 [doi]
PST - ppublish
SO  - Europace. 2018 May 1;20(5):801-807. doi: 10.1093/europace/eux016.