PMID- 28432626
OWN - NLM
STAT- MEDLINE
DCOM- 20171120
LR  - 20181202
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 24
IP  - 20
DP  - 2017 Jul
TI  - Temporal trends of lipophilic persistent organic pollutants in serum from Danish 
      nulliparous pregnant women 2011-2013.
PG  - 16592-16603
LID - 10.1007/s11356-017-8992-7 [doi]
AB  - The use of the lipophilic persistent organic pollutants (POPs) including 
      polychlorinated biphenyls (PCBs) and several organochlorine pesticides (OCPs) has 
      been prohibited for more than 30 years. In this study, we present the temporal 
      trends of the lipophilic POP serum concentrations in Danish nulliparous pregnant 
      women between 2011 and 2013. We randomly selected 197 pregnant women (gestational 
      age 11-13) from the Aarhus Birth Cohort. The concentrations of the lipophilic 
      POPs in the serum samples were analyzed using gas chromatography. The 
      concentrations were corrected for total serum lipids. The statistical analysis 
      was performed by regression analysis with adjustment for age, BMI, gestational 
      age at blood draw, and smoking status. The serum concentrations of PCB 118, 138, 
      153, 156, 170, 180, 187, and hexachlorobenzen, trans-nonachlor, 
      beta-hexachlorocyclohexane (beta-HCH), and p,p'-dichlorodiphenyldichloroethylene were 
      lower in 2013 than in 2011. However, the oxychlordane concentration was lowest in 
      2011. The serum levels of most lipophilic POPs followed downward trends during 
      the study period, which was expected, as these compounds has been banned for many 
      years. The upward trend of oxychlordane was unexpected and presumably a chance 
      finding.
FAU - Bjerregaard-Olesen, Christian
AU  - Bjerregaard-Olesen C
AD  - Centre for Arctic Health & Molecular Epidemiology, Department of Public Health, 
      Aarhus University, Bartholins Alle 2, Build. 1260, DK-8000, Aarhus C, Denmark.
FAU - Long, Manhai
AU  - Long M
AD  - Centre for Arctic Health & Molecular Epidemiology, Department of Public Health, 
      Aarhus University, Bartholins Alle 2, Build. 1260, DK-8000, Aarhus C, Denmark.
FAU - Ghisari, Mandana
AU  - Ghisari M
AD  - Centre for Arctic Health & Molecular Epidemiology, Department of Public Health, 
      Aarhus University, Bartholins Alle 2, Build. 1260, DK-8000, Aarhus C, Denmark.
FAU - Bech, Bodil H
AU  - Bech BH
AD  - Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, 
      Denmark.
FAU - Nohr, Ellen A
AU  - Nohr EA
AD  - Research Unit for Gynaecology and Obstetrics, Institute of Clinical Research, 
      University of Southern Denmark, Odense, Denmark.
FAU - Uldbjerg, Niels
AU  - Uldbjerg N
AD  - Department of Clinical Medicine-Obstetrics and Gynaecology, Aarhus University 
      Hospital, Skejby, Denmark.
FAU - Henriksen, Tine B
AU  - Henriksen TB
AD  - Perinatal Epidemiology Research Unit, Aarhus University Hospital, Skejby, 
      Denmark.
AD  - Department of Pediatrics, Aarhus University Hospital, Skejby, Denmark.
FAU - Olsen, Jorn
AU  - Olsen J
AD  - Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, 
      Denmark.
FAU - Bonefeld-Jorgensen, Eva C
AU  - Bonefeld-Jorgensen EC
AD  - Centre for Arctic Health & Molecular Epidemiology, Department of Public Health, 
      Aarhus University, Bartholins Alle 2, Build. 1260, DK-8000, Aarhus C, Denmark. 
      ebj@ph.au.dk.
LA  - eng
PT  - Journal Article
DEP - 20170421
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene)
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - YM80ODM9PD (beta-hexachlorocyclohexane)
SB  - IM
EIN - Environ Sci Pollut Res Int. 2017 Jul;24(20):16604. PMID: 28616735
MH  - Adult
MH  - Denmark
MH  - Dichlorodiphenyl Dichloroethylene
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Gestational Age
MH  - Hexachlorocyclohexane
MH  - Humans
MH  - Hydrocarbons, Chlorinated/*blood
MH  - Parity
MH  - Pesticides
MH  - Polychlorinated Biphenyls/*blood
MH  - Pregnancy
OTO - NOTNLM
OT  - Determinants
OT  - Organochlorine pesticides
OT  - Polychlorinated biphenyls
OT  - Predictors
OT  - Pregnancy
OT  - Time trends
EDAT- 2017/04/23 06:00
MHDA- 2017/11/29 06:00
CRDT- 2017/04/23 06:00
PHST- 2016/12/12 00:00 [received]
PHST- 2017/04/04 00:00 [accepted]
PHST- 2017/04/23 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
PHST- 2017/04/23 06:00 [entrez]
AID - 10.1007/s11356-017-8992-7 [pii]
AID - 10.1007/s11356-017-8992-7 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2017 Jul;24(20):16592-16603. doi: 
      10.1007/s11356-017-8992-7. Epub 2017 Apr 21.