PMID- 28444307
OWN - NLM
STAT- MEDLINE
DCOM- 20181126
LR  - 20220408
IS  - 1532-2092 (Electronic)
IS  - 1099-5129 (Linking)
VI  - 20
IP  - 1
DP  - 2018 Jan 1
TI  - Left atrial volume predicts atrial fibrillation recurrence after radiofrequency 
      ablation: a meta-analysis.
PG  - 33-42
LID - 10.1093/europace/eux013 [doi]
AB  - AIMS: Left atrial (LA) diameter is a predictor of atrial fibrillation (AF) 
      recurrence following radiofrequency catheter ablation (RFA). However, LA volume 
      (LAV) is more accurate in assessing LA size. Studies evaluating LAV as a 
      predictor of AF recurrence are contradictory; therefore, we performed a 
      meta-analysis to assess whether LAV is an independent predictor of AF recurrence 
      following RFA. METHODS AND RESULTS: All studies reporting LAV/LAV index (LAVi) as 
      a predictor of AF recurrence following RFA were included. For studies reporting 
      mean LAV/ LAVi in patients with and without AF recurrence, standard difference in 
      means (SDM) and standard errors were calculated, and combined using 
      meta-analytical techniques. For studies reporting adjusted odds ratio (OR) for AF 
      recurrence based on LAV/LAVi, log ORs were combined using generic inverse 
      variance. Twenty one studies (3822 subjects) were included. Meta-analysis of 11 
      studies (1559 subjects) reporting LAV, showed that patients with AF recurrence 
      had a higher mean LA volume compared to patients with no recurrence (SDM 0.801; 
      CI 0.387-1.216). Data from 9 studies (1425 subjects) comparing LAVi showed that, 
      patients with AF recurrence had a higher mean LAVi compared to patients with no 
      recurrence (SDM-0.596; CI 0.305-0.888). Thirteen studies (2886 patients) 
      reporting ORs for AF recurrence based on LAV/ LAVi, showed that LAV/LAVi was 
      independently predictive of AF recurrence post-RFA (OR-1.032, CI- 1.012-1.052). 
      CONCLUSIONS: Patients with AF recurrence following RFA have a higher mean 
      LAV/LAVi compared to patients with no recurrence. Large LAV/LAVi increases the 
      odds of AF recurrence post RFA.
CI  - Published on behalf of the European Society of Cardiology. All rights reserved. (c) 
      The Author 2017. For permissions, please email: journals.permissions@oup.com.
FAU - Njoku, Augustine
AU  - Njoku A
AD  - Division of Cardiology and Center for Cardiovascular Diseases & Sciences, LSUHSC 
      Shreveport, LA, USA.
FAU - Kannabhiran, Munish
AU  - Kannabhiran M
AD  - Division of Cardiology and Center for Cardiovascular Diseases & Sciences, LSUHSC 
      Shreveport, LA, USA.
FAU - Arora, Rishi
AU  - Arora R
AD  - Division of Cardiology and Center for Cardiovascular Diseases & Sciences, LSUHSC 
      Shreveport, LA, USA.
FAU - Reddy, Pratap
AU  - Reddy P
AD  - Division of Cardiology and Center for Cardiovascular Diseases & Sciences, LSUHSC 
      Shreveport, LA, USA.
FAU - Gopinathannair, Rakesh
AU  - Gopinathannair R
AD  - Division of Cardiovascular Medicine, University of Louisville, Louisville, KY, 
      USA.
FAU - Lakkireddy, Dhanunjaya
AU  - Lakkireddy D
AD  - Division of Cardiovascular Diseases and Center for Excellence in AF and Complex 
      Arrhythmias, University of Kansas, Kansas City, KS, USA.
FAU - Dominic, Paari
AU  - Dominic P
AD  - Division of Cardiology and Center for Cardiovascular Diseases & Sciences, LSUHSC 
      Shreveport, LA, USA.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PL  - England
TA  - Europace
JT  - Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal 
      of the working groups on cardiac pacing, arrhythmias, and cardiac cellular 
      electrophysiology of the European Society of Cardiology
JID - 100883649
SB  - IM
MH  - Atrial Fibrillation/diagnostic imaging/physiopathology/*surgery
MH  - *Atrial Function, Left
MH  - *Atrial Remodeling
MH  - Catheter Ablation/*adverse effects
MH  - Female
MH  - Heart Atria/diagnostic imaging/physiopathology/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Observational Studies as Topic
MH  - Odds Ratio
MH  - Proportional Hazards Models
MH  - Recurrence
MH  - Risk Assessment
MH  - Risk Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Atrial fibrillation
OT  - Atrial fibrillation recurrence
OT  - Left atrial volume
OT  - Meta-analysis
OT  - Radiofrequency ablation
EDAT- 2017/04/27 06:00
MHDA- 2018/11/27 06:00
CRDT- 2017/04/27 06:00
PHST- 2016/11/17 00:00 [received]
PHST- 2017/01/21 00:00 [accepted]
PHST- 2017/04/27 06:00 [pubmed]
PHST- 2018/11/27 06:00 [medline]
PHST- 2017/04/27 06:00 [entrez]
AID - 3748226 [pii]
AID - 10.1093/europace/eux013 [doi]
PST - ppublish
SO  - Europace. 2018 Jan 1;20(1):33-42. doi: 10.1093/europace/eux013.