PMID- 28444777
OWN - NLM
STAT- MEDLINE
DCOM- 20180312
LR  - 20180312
IS  - 1099-1069 (Electronic)
IS  - 0278-0232 (Linking)
VI  - 36
IP  - 1
DP  - 2018 Feb
TI  - Interphase FISH for BCR-ABL1 rearrangement on neutrophils: A decisive tool to 
      discriminate a lymphoid blast crisis of chronic myeloid leukemia from a de novo 
      BCR-ABL1 positive acute lymphoblastic leukemia.
PG  - 344-348
LID - 10.1002/hon.2416 [doi]
AB  - Discrimination between lymphoid blast crisis of chronic myeloid leukemia (CML) 
      and de novo BCR-ABL1 positive acute lymphoblastic leukemia (ALL) represents a 
      diagnostic challenge because this distinction has a major incidence on the 
      management of patients. Here, we report an uncommon pediatric case of ALL with 
      cryptic ins(22;9)(q11;q34q34) and p190-type BCR-ABL1 transcript. We performed 
      interphase fluorescence in situ hybridization (FISH) for BCR-ABL1 rearrangement 
      on blood neutrophils, which was positive consistent with the diagnosis of 
      lymphoid blast crisis of CML. This case illustrates the major interest of 
      interphase FISH for BCR-ABL1 rearrangement on blood neutrophils as a decisive 
      method to discriminate a lymphoid blast crisis of CML from a de novo BCR-ABL1 
      positive ALL.
CI  - Copyright (c) 2017 John Wiley & Sons, Ltd.
FAU - Balducci, Estelle
AU  - Balducci E
AUID- ORCID: 0000-0002-2634-4288
AD  - APHM, Hopital La Timone, Departement de Genetique Medicale, Marseille, France.
AD  - Aix Marseille Univ, INSERM, GMGF, Marseille, France.
FAU - Loosveld, Marie
AU  - Loosveld M
AD  - APHM, Hopital La Timone, Laboratoire d'Hematologie, Marseille, France.
AD  - Aix Marseille Univ, CNRS, INSERM, CIML, Marseille, France.
FAU - Rahal, Ilhem
AU  - Rahal I
AD  - APHM, Hopital La Timone, Service d'Hematologie et d'Oncologie Pediatrique, 
      Marseille, France.
FAU - Boudjarane, John
AU  - Boudjarane J
AD  - APHM, Hopital La Timone, Departement de Genetique Medicale, Marseille, France.
FAU - Alazard, Emilie
AU  - Alazard E
AD  - APHM, Hopital La Timone, Departement de Genetique Medicale, Marseille, France.
FAU - Missirian, Chantal
AU  - Missirian C
AD  - APHM, Hopital La Timone, Departement de Genetique Medicale, Marseille, France.
FAU - Lafage-Pochitaloff, Marina
AU  - Lafage-Pochitaloff M
AD  - APHM, Hopital La Timone, Departement de Genetique Medicale, Marseille, France.
AD  - Aix Marseille Univ, CNRS, INSERM, CIML, Marseille, France.
FAU - Michel, Gerard
AU  - Michel G
AD  - APHM, Hopital La Timone, Service d'Hematologie et d'Oncologie Pediatrique, 
      Marseille, France.
FAU - Zattara, Helene
AU  - Zattara H
AD  - APHM, Hopital La Timone, Departement de Genetique Medicale, Marseille, France.
AD  - Aix Marseille Univ, INSERM, GMGF, Marseille, France.
LA  - eng
PT  - Case Reports
DEP - 20170425
PL  - England
TA  - Hematol Oncol
JT  - Hematological oncology
JID - 8307268
SB  - IM
MH  - Blast Crisis/*diagnosis
MH  - Child
MH  - Humans
MH  - In Situ Hybridization, Fluorescence/*methods
MH  - Interphase
MH  - Leukemia, Myelogenous, Chronic, BCR-ABL Positive/*genetics
MH  - Male
MH  - Neutrophils/*metabolism
MH  - Precursor Cell Lymphoblastic Leukemia-Lymphoma/*genetics/pathology
OTO - NOTNLM
OT  - BCR-ABL1
OT  - acute lymphoblastic leukemia
OT  - chronic myeloid leukemia
OT  - fluorescence in situ hybridization
OT  - lymphoid blast crisis
OT  - neutrophils
EDAT- 2017/04/27 06:00
MHDA- 2018/03/13 06:00
CRDT- 2017/04/27 06:00
PHST- 2016/10/04 00:00 [received]
PHST- 2017/02/23 00:00 [revised]
PHST- 2017/03/06 00:00 [accepted]
PHST- 2017/04/27 06:00 [pubmed]
PHST- 2018/03/13 06:00 [medline]
PHST- 2017/04/27 06:00 [entrez]
AID - 10.1002/hon.2416 [doi]
PST - ppublish
SO  - Hematol Oncol. 2018 Feb;36(1):344-348. doi: 10.1002/hon.2416. Epub 2017 Apr 25.