PMID- 28447186
OWN - NLM
STAT- MEDLINE
DCOM- 20180326
LR  - 20181113
IS  - 1439-6327 (Electronic)
IS  - 1439-6319 (Linking)
VI  - 117
IP  - 7
DP  - 2017 Jul
TI  - Comparison of the recovery response from high-intensity and high-volume 
      resistance exercise in trained men.
PG  - 1287-1298
LID - 10.1007/s00421-017-3598-9 [doi]
AB  - PURPOSE: The purpose of this study was to compare the physiological responses of 
      a high-volume (HV; 8 sets of 10 repetitions) versus high-intensity (HI; 8 sets of 
      3 repetitions) exercise protocol in resistance-trained men. METHODS: Twelve men 
      (24.5 +/- 4.2 years; 82.3 +/- 8.4 kg; 175.2 +/- 5.5 cm) with 6.3 +/- 3.4 years of 
      resistance training experience performed each protocol in a counterbalanced, 
      randomized order. Performance [counter movement jump peak power (CMJP), 
      isokinetic (ISOK) and isometric leg extension (MVIC), isometric mid-thigh pull 
      (IMTP), and isometric squat (ISQ)] and muscle morphological [cross-sectional area 
      (CSA) of vastus lateralis] assessments were performed at baseline (BL), 30-min 
      (P-30 min), 24-h (P-24 h), 48-h (P-48 h), and 72-h (P-72 h) post-exercise for 
      each testing session. In addition, endocrine (testosterone and cortisol), 
      inflammatory [interleukin-6 (IL-6) and C-reactive protein (CRP)], and markers of 
      muscle damage [creatine kinase (CK), lactate dehydrogenase (LDH), and myoglobin 
      (Mb)] were assessed at the same time points. RESULTS: Significantly greater 
      reductions in CMJP (p < 0.001), and peak torque during both ISOK (p = 0.003) and 
      MVIC (p = 0.008) at P-30 min were detected in HV compared to HI protocol. MVIC 
      was still impaired at P-72 h following the HV protocol, while no differences were 
      noted following HI. Markers of muscle damage (LDH, CK, and Mb) were significantly 
      elevated following both HV and HI (p < 0.05), while cortisol and IL-6 
      concentrations were significantly elevated at P-30 min following HV only 
      (p < 0.001 and p < 0.05, respectively). CONCLUSIONS: Results indicate that 
      high-volume resistance exercise results in greater performance deficits, and a 
      greater extent of muscle damage, than a bout of high-intensity resistance 
      exercise.
FAU - Bartolomei, Sandro
AU  - Bartolomei S
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA. sandro.bartolomei@ucf.edu.
FAU - Sadres, Eliahu
AU  - Sadres E
AD  - The Nat Holman School for Coaches and Instructors, Wingate Institute for Physical 
      Education and Sport, Netanya, Israel.
FAU - Church, David D
AU  - Church DD
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
FAU - Arroyo, Eliott
AU  - Arroyo E
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
FAU - Gordon, Joseph A III
AU  - Gordon JA III
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
FAU - Varanoske, Alyssa N
AU  - Varanoske AN
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
FAU - Wang, Ran
AU  - Wang R
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
FAU - Beyer, Kyle S
AU  - Beyer KS
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
FAU - Oliveira, Leonardo P
AU  - Oliveira LP
AD  - College of Medicine, University of Central Florida, Orlando, FL, 32766, USA.
FAU - Stout, Jeffrey R
AU  - Stout JR
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
FAU - Hoffman, Jay R
AU  - Hoffman JR
AD  - Sport and Exercise Science, University of Central Florida, Orlando, FL, 32766, 
      USA.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20170426
PL  - Germany
TA  - Eur J Appl Physiol
JT  - European journal of applied physiology
JID - 100954790
RN  - 0 (Interleukin-6)
RN  - 0 (Myoglobin)
RN  - 3XMK78S47O (Testosterone)
RN  - 9007-41-4 (C-Reactive Protein)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
RN  - EC 2.7.3.2 (Creatine Kinase)
RN  - WI4X0X7BPJ (Hydrocortisone)
SB  - IM
MH  - Adult
MH  - C-Reactive Protein/metabolism
MH  - Creatine Kinase/blood
MH  - High-Intensity Interval Training/*adverse effects
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Interleukin-6/blood
MH  - Isometric Contraction
MH  - L-Lactate Dehydrogenase/blood
MH  - Leg/physiology
MH  - Male
MH  - Muscle, Skeletal/metabolism/*physiology
MH  - Myalgia/etiology/physiopathology/*rehabilitation
MH  - Myoglobin/metabolism
MH  - Recovery of Function
MH  - Resistance Training/*adverse effects
MH  - Testosterone/blood
OTO - NOTNLM
OT  - Cortisol
OT  - Inflammation
OT  - Muscle damage
OT  - Performance
OT  - Resistance training
OT  - Testosterone
EDAT- 2017/04/28 06:00
MHDA- 2018/03/27 06:00
CRDT- 2017/04/28 06:00
PHST- 2016/11/01 00:00 [received]
PHST- 2017/03/27 00:00 [accepted]
PHST- 2017/04/28 06:00 [pubmed]
PHST- 2018/03/27 06:00 [medline]
PHST- 2017/04/28 06:00 [entrez]
AID - 10.1007/s00421-017-3598-9 [pii]
AID - 10.1007/s00421-017-3598-9 [doi]
PST - ppublish
SO  - Eur J Appl Physiol. 2017 Jul;117(7):1287-1298. doi: 10.1007/s00421-017-3598-9. 
      Epub 2017 Apr 26.