PMID- 28452991
OWN - NLM
STAT- MEDLINE
DCOM- 20180109
LR  - 20181113
IS  - 1476-5454 (Electronic)
IS  - 0950-222X (Print)
IS  - 0950-222X (Linking)
VI  - 31
IP  - 9
DP  - 2017 Sep
TI  - Focal choroidal excavation-morphological features and clinical correlation.
PG  - 1373-1379
LID - 10.1038/eye.2017.71 [doi]
AB  - PurposeTo describe and correlate the morphological and clinical features of focal 
      choroidal excavation (FCE).MethodsThis is a consecutive case series from the 
      review of the 4436 optical coherence tomography scans performed by Kowloon East 
      Cluster Ophthalmic Service from 1 August 2014-31 January 2016. Statistical 
      analysis was performed on SPSS 18.0 (SPSS, Chicago, IL, USA). A significance 
      level of P<0.05 was taken.ResultsAll 16 patients with FCE had unilateral 
      involvement. The mean age of diagnosis was 52.56+/-14.00. The mean greatest linear 
      dimension (GLD) of FCE was 636.25+/-265.11 mum. The mean choroidal thickness was 
      183.63+/-52.39 mum. Fourteen FCEs (87.5%) were conforming and two were 
      non-conforming (12.5%). In the eyes with FCE, concurrent macular pathology was 
      present in four cases (25.0%). Tractional pathologies of macular pucker and 
      macular scar corresponded to the two non-conforming FCEs in the series. 
      Polypoidal choroidal vasculopathy (PCV) and lacquer crack had a close topographic 
      relationship with the FCE. The mean GLD was significantly larger in eyes with 
      concurrent macular pathology than those without (878.00 vs 555.67 mum, P=0.029). 
      In the fellow eyes, concurrent macular pathology was present in 5 cases (31.3%): 
      PCV in 3 cases and chronic central serous chorioretinopathy in 2 
      cases.ConclusionAs a significant proportion of FCE is associated with concurrent 
      macular pathology in the involved or fellow eye, angiography for both eyes is 
      recommended even for asymptomatic cases. The GLD of FCE may have clinical value 
      in risk stratification.
FAU - Chung, C Y
AU  - Chung CY
AD  - Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.
AD  - Department of Ophthalmology, Tseung Kwan O Hospital, Kowloon, Hong Kong.
AD  - Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong 
      Kong, Hong Kong, Hong Kong.
FAU - Li, S H
AU  - Li SH
AD  - Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.
AD  - Department of Ophthalmology, Tseung Kwan O Hospital, Kowloon, Hong Kong.
AD  - Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong 
      Kong, Hong Kong, Hong Kong.
FAU - Li, K K W
AU  - Li KKW
AD  - Department of Ophthalmology, United Christian Hospital, Kowloon, Hong Kong.
AD  - Department of Ophthalmology, Tseung Kwan O Hospital, Kowloon, Hong Kong.
AD  - Department of Ophthalmology, LKS Faculty of Medicine, The University of Hong 
      Kong, Hong Kong, Hong Kong.
LA  - eng
PT  - Journal Article
DEP - 20170428
PL  - England
TA  - Eye (Lond)
JT  - Eye (London, England)
JID - 8703986
SB  - IM
MH  - Adult
MH  - Aged
MH  - Central Serous Chorioretinopathy/diagnosis
MH  - Choroid/*pathology
MH  - Choroid Diseases/*pathology
MH  - Choroidal Neovascularization/diagnosis
MH  - Female
MH  - Fluorescein Angiography
MH  - Humans
MH  - Macular Degeneration/diagnosis
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence
MH  - Visual Acuity/physiology
PMC - PMC5601452
COIS- The authors declare no conflict of interest.
EDAT- 2017/04/30 06:00
MHDA- 2018/01/10 06:00
PMCR- 2018/09/01
CRDT- 2017/04/29 06:00
PHST- 2016/11/21 00:00 [received]
PHST- 2017/03/26 00:00 [accepted]
PHST- 2017/04/30 06:00 [pubmed]
PHST- 2018/01/10 06:00 [medline]
PHST- 2017/04/29 06:00 [entrez]
PHST- 2018/09/01 00:00 [pmc-release]
AID - eye201771 [pii]
AID - 10.1038/eye.2017.71 [doi]
PST - ppublish
SO  - Eye (Lond). 2017 Sep;31(9):1373-1379. doi: 10.1038/eye.2017.71. Epub 2017 Apr 28.