PMID- 28453868
OWN - NLM
STAT- MEDLINE
DCOM- 20180730
LR  - 20220408
IS  - 1600-0838 (Electronic)
IS  - 0905-7188 (Linking)
VI  - 28
IP  - 1
DP  - 2018 Jan
TI  - Combined aerobic and resistance training decreases inflammation markers in 
      healthy men.
PG  - 40-47
LID - 10.1111/sms.12906 [doi]
AB  - Our primary aim was to study the effects of 24 weeks of combined aerobic and 
      resistance training performed on the same day or on different days on 
      inflammation markers. Physically active, healthy young men were randomly divided 
      into three groups that performed: aerobic and resistance training consecutively 
      in the same training session (SS) 2-3 days wk(-1) or on alternating days (AD) 4-6 
      days wk(-1) as well as control (C). The total training volume was matched in the 
      training groups. The control group was asked to maintain their habitual physical 
      activity and exercise level. Maximal leg press strength (1RM) and peak oxygen 
      uptake (VO2(peak) ) were measured. Abdominal fat mass was estimated with 
      dual-energy absorptiometry (DXA). High-sensitivity C-reactive protein (hs-CRP), 
      interleukin-6 (IL-6), monocyte chemoattractant protein 1 (MCP-1), tumor necrosis 
      factor alpha (TNF-alpha), and adipocytokines resistin, adiponectin, and leptin were 
      analyzed from plasma samples. Training significantly reduced circulating hs-CRP, 
      leptin, and resistin in both training groups (P<.05), whereas MCP-1 and TNF-alpha 
      decreased only in AD (P<.05). Significant correlations were observed between 
      changes in abdominal fat mass and corresponding changes in MCP-1, leptin, 
      adiponectin, and resistin. Long-term combined aerobic and resistance training 
      reduced markers of subclinical inflammation in healthy young men. The results 
      indicate that a higher frequency of individual exercise sessions might be more 
      beneficial with respect to the anti-inflammatory effects of physical activity. 
      The decreases in inflammation markers seem to be related to decreases in 
      abdominal fat mass.
CI  - (c) 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Ihalainen, J K
AU  - Ihalainen JK
AUID- ORCID: 0000-0001-9428-4689
AD  - Neuromuscular Research Center, Biology of Physical Activity, Faculty of Sport and 
      Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
FAU - Schumann, M
AU  - Schumann M
AD  - Neuromuscular Research Center, Biology of Physical Activity, Faculty of Sport and 
      Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
AD  - Department of Molecular and Cellular Sport Medicine, German Sport University 
      Cologne, Cologne, Germany.
FAU - Eklund, D
AU  - Eklund D
AD  - Neuromuscular Research Center, Biology of Physical Activity, Faculty of Sport and 
      Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
FAU - Hamalainen, M
AU  - Hamalainen M
AD  - Faculty of Medicine and Life Sciences, The Immunopharmacology Research Group, 
      University of Tampere, Tampere University Hospital, Tampere, Finland.
FAU - Moilanen, E
AU  - Moilanen E
AD  - Faculty of Medicine and Life Sciences, The Immunopharmacology Research Group, 
      University of Tampere, Tampere University Hospital, Tampere, Finland.
FAU - Paulsen, G
AU  - Paulsen G
AD  - The Norwegian Olympic and Paralympic Committee and Confederation of Sports, Oslo, 
      Norway.
AD  - Norwegian School of Sport Sciences, Oslo, Norway.
FAU - Hakkinen, K
AU  - Hakkinen K
AD  - Neuromuscular Research Center, Biology of Physical Activity, Faculty of Sport and 
      Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
FAU - Mero, A A
AU  - Mero AA
AD  - Neuromuscular Research Center, Biology of Physical Activity, Faculty of Sport and 
      Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20170613
PL  - Denmark
TA  - Scand J Med Sci Sports
JT  - Scandinavian journal of medicine & science in sports
JID - 9111504
RN  - 0 (ADIPOQ protein, human)
RN  - 0 (Adiponectin)
RN  - 0 (Biomarkers)
RN  - 0 (CCL2 protein, human)
RN  - 0 (Chemokine CCL2)
RN  - 0 (IL6 protein, human)
RN  - 0 (Interleukin-6)
RN  - 0 (Leptin)
RN  - 0 (RETN protein, human)
RN  - 0 (Resistin)
RN  - 0 (Tumor Necrosis Factor-alpha)
RN  - 9007-41-4 (C-Reactive Protein)
SB  - IM
MH  - Abdominal Fat
MH  - Adiponectin/blood
MH  - Adult
MH  - Biomarkers/blood
MH  - Body Composition
MH  - C-Reactive Protein/analysis
MH  - Chemokine CCL2/blood
MH  - *Exercise
MH  - Humans
MH  - Inflammation/*blood
MH  - Interleukin-6/blood
MH  - Leptin/blood
MH  - Male
MH  - Oxygen Consumption
MH  - *Resistance Training
MH  - Resistin/blood
MH  - Tumor Necrosis Factor-alpha/blood
OTO - NOTNLM
OT  - abdominal fat
OT  - adipokines
OT  - low-grade inflammation
OT  - physical exercise
EDAT- 2017/04/30 06:00
MHDA- 2018/07/31 06:00
CRDT- 2017/04/29 06:00
PHST- 2017/04/25 00:00 [accepted]
PHST- 2017/04/30 06:00 [pubmed]
PHST- 2018/07/31 06:00 [medline]
PHST- 2017/04/29 06:00 [entrez]
AID - 10.1111/sms.12906 [doi]
PST - ppublish
SO  - Scand J Med Sci Sports. 2018 Jan;28(1):40-47. doi: 10.1111/sms.12906. Epub 2017 
      Jun 13.