PMID- 28455768
OWN - NLM
STAT- MEDLINE
DCOM- 20180424
LR  - 20181202
IS  - 1590-3478 (Electronic)
IS  - 1590-1874 (Linking)
VI  - 38
IP  - 8
DP  - 2017 Aug
TI  - Sleep disturbance in mild cognitive impairment: a systematic review of objective 
      measures.
PG  - 1363-1371
LID - 10.1007/s10072-017-2975-9 [doi]
AB  - Sleep disturbance frequently occurs in patients with mild cognitive impairment 
      (MCI) and appears to be involved in the cellular and molecular mechanisms of 
      cognitive decline. The aim of this systematic review is to clarify whether 
      patients with MCI demonstrate alterations in certain sleep parameters: total 
      sleep time (TST), sleep efficiency (SE), sleep latency (SL), rapid eye movement 
      latency (REML), percent of rapid eye movement (REM%), arousal index (AI), wake 
      after sleep onset (WASO), slow-wave sleep (SWS), periodic leg movement in sleep 
      (PLMS), and cyclic alternating pattern (CAP) through polysomnography (PSG) and 
      actigraphy. Databases including PubMed, Web of Science, Embase, ScienceDirect, 
      Cochrane, CBM, CNKI, Wanfang Data, and VIP were searched up to January 2016 to 
      collect literature on the correlation between sleep disturbance and MCI as 
      assessed by objective measures. Meta-analysis was conducted using the Review 
      Manager 5.3 software. A total of ten case-control studies involving 225 MCI 
      patients and 235 healthy elders (HE) were deemed eligible and included in our 
      meta-analysis. Every type of sleep disturbance was present in our studies with 
      significant differences in the MCI subtypes. Compared with HE, overall MCI 
      patients as a group expressed more SL and less SE; MCI patients showed less TST 
      and SE and more SL and CAP; patients with amnestic mild cognitive impairment 
      (aMCI) had less AI; patients with non-amnestic mild cognitive impairment (naMCI) 
      had more TST and less AI. Patients with naMCI expressed more AI than those with 
      aMCI. The results indicate that MCI patients might experience more serious sleep 
      disturbance and that different MCI subtypes have different patterns of sleep 
      disturbance.
FAU - Hu, Mingyue
AU  - Hu M
AD  - College of Nursing, Jilin University, 965 Xinjiang Road, Changchun, 130021, 
      China.
FAU - Zhang, Ping
AU  - Zhang P
AD  - College of Nursing, Jilin University, 965 Xinjiang Road, Changchun, 130021, 
      China.
FAU - Li, Chen
AU  - Li C
AD  - College of Nursing, Jilin University, 965 Xinjiang Road, Changchun, 130021, 
      China.
FAU - Tan, Yongfei
AU  - Tan Y
AD  - Department of Pharmacology, College of Basic Medical Sciences, Jilin University, 
      Changchun, China.
FAU - Li, Guichen
AU  - Li G
AD  - College of Nursing, Jilin University, 965 Xinjiang Road, Changchun, 130021, 
      China.
FAU - Xu, Duo
AU  - Xu D
AD  - College of Nursing, Jilin University, 965 Xinjiang Road, Changchun, 130021, 
      China.
FAU - Chen, Li
AU  - Chen L
AD  - College of Nursing, Jilin University, 965 Xinjiang Road, Changchun, 130021, 
      China. chen_care@126.com.
AD  - Department of Pharmacology, College of Basic Medical Sciences, Jilin University, 
      Changchun, China. chen_care@126.com.
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20170428
PL  - Italy
TA  - Neurol Sci
JT  - Neurological sciences : official journal of the Italian Neurological Society and 
      of the Italian Society of Clinical Neurophysiology
JID - 100959175
SB  - IM
MH  - Cognitive Dysfunction/*complications
MH  - Humans
MH  - Sleep Wake Disorders/*diagnosis/*etiology
OTO - NOTNLM
OT  - Actigraphy
OT  - Meta-analysis
OT  - Mild cognitive impairment
OT  - PSG
OT  - Sleep disturbance
EDAT- 2017/04/30 06:00
MHDA- 2018/04/25 06:00
CRDT- 2017/04/30 06:00
PHST- 2016/11/21 00:00 [received]
PHST- 2017/04/19 00:00 [accepted]
PHST- 2017/04/30 06:00 [pubmed]
PHST- 2018/04/25 06:00 [medline]
PHST- 2017/04/30 06:00 [entrez]
AID - 10.1007/s10072-017-2975-9 [pii]
AID - 10.1007/s10072-017-2975-9 [doi]
PST - ppublish
SO  - Neurol Sci. 2017 Aug;38(8):1363-1371. doi: 10.1007/s10072-017-2975-9. Epub 2017 
      Apr 28.