PMID- 28459413 OWN - NLM STAT- MEDLINE DCOM- 20180515 LR - 20201209 IS - 2095-4352 (Print) VI - 29 IP - 1 DP - 2017 Jan TI - [Advance on human umbilical cord mesenchymal stem cells for treatment of ALI in severe burns]. PG - 90-96 LID - 10.3760/cma.j.issn.2095-4352.2017.01.020 [doi] AB - Severe burn is often accompanied by multiple organ damage. Acute lung injury (ALI) is one of the most common complications, and often occurs in the early stage of severe burns. If it is not treated in time, it will progress to acute respiratory distress syndrome (ARDS), which will be a serious threat to the lives of patients. At present, the treatment of ALI in patients with severe burn is still remained in some common ways, such as the liquid resuscitation, the primary wound treatment, ventilation support, and anti-infection. In recently, human umbilical cord mesenchymal stem cells (hUCMSCs) have been found having some good effects on ALI caused by various causes, but few reports on the efficacy of ALI caused by severe burns were reported. By reviewing the mechanism of stem cell therapy for ALI, therapeutic potential of hUCMSCs in the treatment of severe burns with ALI and a new approach for clinical treatment was provided. FAU - Wang, Yu AU - Wang Y AD - Graduate School, Jinzhou Medical University, Jinzhou 121000, Liaoning, China (Wang Y); Department of Pediatrics, the First Affiliated Hospital to PLA General Hospital, Beijing 100048, China (Hu XH). Corresponding author: Hu Xiaohong, Email: xhh304@163.com. FAU - Hu, Xiaohong AU - Hu X LA - chi PT - Journal Article PL - China TA - Zhonghua Wei Zhong Bing Ji Jiu Yi Xue JT - Zhonghua wei zhong bing ji jiu yi xue JID - 101604552 SB - IM MH - Acute Lung Injury MH - Burns MH - Humans MH - Lung MH - *Mesenchymal Stem Cells MH - Respiratory Distress Syndrome MH - Umbilical Cord EDAT- 2017/05/02 06:00 MHDA- 2018/05/16 06:00 CRDT- 2017/05/02 06:00 PHST- 2017/05/02 06:00 [entrez] PHST- 2017/05/02 06:00 [pubmed] PHST- 2018/05/16 06:00 [medline] AID - 10.3760/cma.j.issn.2095-4352.2017.01.020 [doi] PST - ppublish SO - Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2017 Jan;29(1):90-96. doi: 10.3760/cma.j.issn.2095-4352.2017.01.020.