PMID- 28471129 OWN - NLM STAT- MEDLINE DCOM- 20170606 LR - 20170606 IS - 1359-4117 (Print) IS - 1359-4117 (Linking) VI - 11 IP - 3 DP - 2016 Jul TI - Management of a multiple endocrine neoplasia type 1 during pregnancy: A case report and review of the literature. PG - 217-220 AB - Multiple Endocrine Neoplasia Type 1 (MEN1) or Wermer's syndrome is a rare hereditary endocrine syndrome with high penetrance caused by mutations in MEN1 tumor suppressor gene. MEN1 is characterized by hyperplasia or tumoral enlargement in a number of endocrine organs (parathyroid glands, pancreas, pituitary gland, adrenal gland) and it could be hormonally active or inactive. MEN1 is a significant cause of morbidity due to hormone secretion and mass effect. Since it is a rare condition, there are no guidelines with respect to the follow-up of pregnant women with MEN1. Herein, we aimed to present the diagnosis and gestational follow-up of a 29-year-old pregnant with MEN1 syndrome. CI - (c) 2016 Old City Publishing, Inc. FAU - Daglar, Halil Korkut AU - Daglar HK AD - Department of Perinatology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey. FAU - Kirbas, Ayse AU - Kirbas A AD - Department of Perinatology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey. FAU - Biberoglu, Ebru AU - Biberoglu E AD - Department of Perinatology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey. FAU - Laleli, Bergen AU - Laleli B AD - Department of Perinatology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey. FAU - Danisman, Nuri AU - Danisman N AD - Department of Perinatology, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, Turkey. LA - eng PT - Case Reports PT - Journal Article PT - Review PL - United States TA - J Exp Ther Oncol JT - Journal of experimental therapeutics & oncology JID - 9604933 RN - 0 (MEN1 protein, human) RN - 0 (Proto-Oncogene Proteins) SB - IM MH - Adult MH - DNA Mutational Analysis MH - Female MH - Genetic Predisposition to Disease MH - Humans MH - Live Birth MH - Multiple Endocrine Neoplasia Type 1/diagnosis/genetics/*therapy MH - Mutation MH - Phenotype MH - Pregnancy MH - Pregnancy Complications, Neoplastic/diagnosis/genetics/*therapy MH - Proto-Oncogene Proteins/genetics MH - Treatment Outcome OTO - NOTNLM OT - calcium OT - insulin OT - parathyroid OT - pituitary OT - pregnancy EDAT- 2017/05/05 06:00 MHDA- 2017/06/07 06:00 CRDT- 2017/05/05 06:00 PHST- 2015/09/30 00:00 [received] PHST- 2015/12/14 00:00 [revised] PHST- 2015/12/18 00:00 [accepted] PHST- 2017/05/05 06:00 [entrez] PHST- 2017/05/05 06:00 [pubmed] PHST- 2017/06/07 06:00 [medline] AID - 150930-AK [pii] PST - ppublish SO - J Exp Ther Oncol. 2016 Jul;11(3):217-220.