PMID- 28473868 OWN - NLM STAT- MEDLINE DCOM- 20171109 LR - 20191210 IS - 1748-6718 (Electronic) IS - 1748-670X (Print) IS - 1748-670X (Linking) VI - 2017 DP - 2017 TI - A Novel Fusion Framework Based on Adaptive PCNN in NSCT Domain for Whole-Body PET and CT Images. PG - 8407019 LID - 10.1155/2017/8407019 [doi] LID - 8407019 AB - The PET and CT fusion images, combining the anatomical and functional information, have important clinical meaning. This paper proposes a novel fusion framework based on adaptive pulse-coupled neural networks (PCNNs) in nonsubsampled contourlet transform (NSCT) domain for fusing whole-body PET and CT images. Firstly, the gradient average of each pixel is chosen as the linking strength of PCNN model to implement self-adaptability. Secondly, to improve the fusion performance, the novel sum-modified Laplacian (NSML) and energy of edge (EOE) are extracted as the external inputs of the PCNN models for low- and high-pass subbands, respectively. Lastly, the rule of max region energy is adopted as the fusion rule and different energy templates are employed in the low- and high-pass subbands. The experimental results on whole-body PET and CT data (239 slices contained by each modality) show that the proposed framework outperforms the other six methods in terms of the seven commonly used fusion performance metrics. FAU - Song, Zhiying AU - Song Z AUID- ORCID: 0000-0002-3849-6238 AD - Software College, Northeastern University, Shenyang 110819, China. FAU - Jiang, Huiyan AU - Jiang H AUID- ORCID: 0000-0002-1428-8776 AD - Software College, Northeastern University, Shenyang 110819, China. FAU - Li, Siqi AU - Li S AD - Software College, Northeastern University, Shenyang 110819, China. LA - eng PT - Journal Article DEP - 20170403 PL - United States TA - Comput Math Methods Med JT - Computational and mathematical methods in medicine JID - 101277751 SB - IM MH - *Algorithms MH - Humans MH - Image Interpretation, Computer-Assisted/*methods/standards MH - *Neural Networks, Computer MH - *Positron-Emission Tomography MH - *Tomography, X-Ray Computed PMC - PMC5394910 EDAT- 2017/05/06 06:00 MHDA- 2017/11/10 06:00 PMCR- 2017/04/03 CRDT- 2017/05/06 06:00 PHST- 2017/01/09 00:00 [received] PHST- 2017/03/12 00:00 [revised] PHST- 2017/03/28 00:00 [accepted] PHST- 2017/05/06 06:00 [entrez] PHST- 2017/05/06 06:00 [pubmed] PHST- 2017/11/10 06:00 [medline] PHST- 2017/04/03 00:00 [pmc-release] AID - 10.1155/2017/8407019 [doi] PST - ppublish SO - Comput Math Methods Med. 2017;2017:8407019. doi: 10.1155/2017/8407019. Epub 2017 Apr 3.