PMID- 28476369 OWN - NLM STAT- MEDLINE DCOM- 20190319 LR - 20190319 IS - 1526-3231 (Electronic) IS - 0749-8063 (Linking) VI - 33 IP - 5 DP - 2017 May TI - Editorial Commentary: Pain and Stress Response After Shoulder Arthroscopic Rotator Cuff Repair: Does Interscalene Block Make a Clinically Important Difference? PG - 927-928 LID - S0749-8063(17)30059-2 [pii] LID - 10.1016/j.arthro.2017.01.013 [doi] AB - Pain control after arthroscopic rotator cuff repair will invariably encompass a multimodal approach which will include, in some form, an anesthetic block. The authors of "Effects of a Single-Dose Interscalene Block on Pain and Stress Biomarkers in Patients Undergoing Arthroscopic Rotator Cuff Repair: A Randomized Controlled Trial" demonstrate better pain control and a decrease in levels of the stress biomarker insulin with the use of a single-dose interscalene block (SISB) and general anesthesia compared to general anesthesia alone. But a closer look at the minimal clinically important difference (MCID) becomes critically important when interpreting the results as the effect may be less than anticipated and the "rebound effect" plays an important role. The notoriously painful rotator cuff repair may need further evaluation beyond the first several days when looking from the patients' perspectives to impact overall satisfaction and utility. CI - Copyright (c) 2017 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved. FAU - Rossi, Michael J AU - Rossi MJ LA - eng PT - Comment PT - Editorial PL - United States TA - Arthroscopy JT - Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association JID - 8506498 RN - 0 (Anesthetics, Local) RN - 0 (Biomarkers) SB - IM CON - Arthroscopy. 2017 May;33(5):918-926. PMID: 27988164 MH - Anesthetics, Local MH - Arthroscopy MH - Biomarkers MH - Humans MH - Pain, Postoperative MH - Prospective Studies MH - Rotator Cuff MH - *Rotator Cuff Injuries MH - *Shoulder EDAT- 2017/05/10 06:00 MHDA- 2019/03/20 06:00 CRDT- 2017/05/07 06:00 PHST- 2016/12/29 00:00 [received] PHST- 2017/01/08 00:00 [revised] PHST- 2017/01/19 00:00 [accepted] PHST- 2017/05/07 06:00 [entrez] PHST- 2017/05/10 06:00 [pubmed] PHST- 2019/03/20 06:00 [medline] AID - S0749-8063(17)30059-2 [pii] AID - 10.1016/j.arthro.2017.01.013 [doi] PST - ppublish SO - Arthroscopy. 2017 May;33(5):927-928. doi: 10.1016/j.arthro.2017.01.013.