PMID- 28483150 OWN - NLM STAT- MEDLINE DCOM- 20170905 LR - 20170906 IS - 1552-6259 (Electronic) IS - 0003-4975 (Linking) VI - 104 IP - 2 DP - 2017 Aug TI - De Novo Aortic Regurgitation After Continuous-Flow Left Ventricular Assist Device Implantation. PG - 704-711 LID - S0003-4975(17)30251-5 [pii] LID - 10.1016/j.athoracsur.2017.01.114 [doi] AB - Continuous-flow left ventricular assist devices (cf-LVAD) play an important role in the management of patients with advanced heart failure. De novo aortic regurgitation after cf-LVAD implantation may adversely impact device performance. We performed a systematic search of PubMed, SCOPUS, and Cochrane Library for articles reporting on the incidence and predictors of de novo aortic regurgitation among cf-LVAD recipients. Eight studies totaling 548 patients were identified in the meta-analysis. The pooled incidence of de novo AR across the analyzed studies was 37%. Factors influencing its development and progression are older age, persistent aortic valve closure, being female, and duration of cf-LVAD support. CI - Copyright (c) 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. FAU - Gasparovic, Hrvoje AU - Gasparovic H AD - Department of Cardiac Surgery, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. Electronic address: hgasparovic@gmail.com. FAU - Kopjar, Tomislav AU - Kopjar T AD - Department of Cardiac Surgery, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. FAU - Saeed, Diyar AU - Saeed D AD - Clinic for Cardiovascular Surgery, Heinrich-Heine University Dusseldorf, Dusseldorf, Germany. FAU - Cikes, Maja AU - Cikes M AD - Department of Cardiology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. FAU - Svetina, Lucija AU - Svetina L AD - Department of Cardiac Surgery, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. FAU - Petricevic, Mate AU - Petricevic M AD - Department of Cardiac Surgery, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. FAU - Lovric, Daniel AU - Lovric D AD - Department of Cardiology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. FAU - Milicic, Davor AU - Milicic D AD - Department of Cardiology, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. FAU - Biocina, Bojan AU - Biocina B AD - Department of Cardiac Surgery, University Hospital Center Zagreb, University of Zagreb School of Medicine, Zagreb, Croatia. LA - eng PT - Journal Article PT - Review DEP - 20170506 PL - Netherlands TA - Ann Thorac Surg JT - The Annals of thoracic surgery JID - 15030100R SB - IM MH - Aortic Valve Insufficiency/*etiology MH - Disease Progression MH - Heart Failure/physiopathology/*surgery MH - Heart-Assist Devices/*adverse effects MH - Humans MH - *Postoperative Complications MH - Ventricular Function, Left/*physiology EDAT- 2017/05/10 06:00 MHDA- 2017/09/07 06:00 CRDT- 2017/05/10 06:00 PHST- 2016/07/06 00:00 [received] PHST- 2016/12/21 00:00 [revised] PHST- 2017/01/30 00:00 [accepted] PHST- 2017/05/10 06:00 [pubmed] PHST- 2017/09/07 06:00 [medline] PHST- 2017/05/10 06:00 [entrez] AID - S0003-4975(17)30251-5 [pii] AID - 10.1016/j.athoracsur.2017.01.114 [doi] PST - ppublish SO - Ann Thorac Surg. 2017 Aug;104(2):704-711. doi: 10.1016/j.athoracsur.2017.01.114. Epub 2017 May 6.