PMID- 28491458 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220331 IS - 2055-1169 (Print) IS - 2055-1169 (Electronic) IS - 2055-1169 (Linking) VI - 3 IP - 1 DP - 2017 Jan-Jun TI - Caecocolic intussusception associated with a caecal polyp and concurrent hepatocellular carcinoma in a cat. PG - 2055116917706652 LID - 10.1177/2055116917706652 [doi] LID - 2055116917706652 AB - CASE SUMMARY: A 17-year-old female neutered domestic shorthair cat presented for several days of reduced faecal volume and a rectal prolapse. Physical examination revealed a 2 cm rectal prolapse, hepatomegaly and a low body condition score of 3/9. Haematology and biochemistry revealed a mild non-regenerative anaemia (haematocrit 24.5%; reference interval [RI] 30.3-52.3%), a mild mature neutrophilia (16.21 x 10(9)/l; RI 1.48-10.29 x 10(9)/l) and a mild increase in alanine aminotransferase activity (222 IU/l; RI 12-130 IU/l). Abdominal radiographs identified hepatomegaly. The rectal prolapse was reduced under general anaesthesia. Abdominal ultrasound identified a caecocolic intussusception and a large hepatic mass. Thoracic radiographs were unremarkable. Hepatic fine-needle aspirate cytology revealed well-differentiated hepatocytes. A typhlectomy was performed and the quadrate liver lobe, with mass, was resected. Gross examination of the caecum identified a focal polyp; histopathology showed moderate plasmacytic-lymphocytic typhlitis and reactive mucosal-associated lymphoid tissue. The hepatic mass was diagnosed as a well-differentiated hepatocellular carcinoma. Six weeks postoperatively the cat had gained 0.5 kg, had an improved body condition score of 5/9 and resolution of clinical signs. The cat died acutely 1 year later from an unknown cause. RELEVANCE AND NOVEL INFORMATION: Caecocolic intussusception is rare in cats and uncommon in dogs. This is the third report in a cat and the first associated with a caecal polyp. As reported in dogs, the outcome following surgery was good. Hepatocellular carcinoma is a rarely reported feline neoplasm, which may have a good prognosis with surgical resection. FAU - Boland, Lara AU - Boland L AD - Valentine Charlton Cat Centre, Sydney School of Veterinary Science, Faculty of Science, University of Sydney, NSW, Australia. FAU - Lindsay, Scott AU - Lindsay S AD - Veterinary Pathology Diagnostic Services, Sydney School of Veterinary Science, Faculty of Science, University of Sydney, NSW, Australia. AD - School of Animal and Veterinary Sciences, Faculty of Science, The University of Adelaide, SA, Australia. FAU - Brunel, Laurencie AU - Brunel L AD - Valentine Charlton Cat Centre, Sydney School of Veterinary Science, Faculty of Science, University of Sydney, NSW, Australia. FAU - Podadera, Juan AU - Podadera J AD - Valentine Charlton Cat Centre, Sydney School of Veterinary Science, Faculty of Science, University of Sydney, NSW, Australia. FAU - Bennett, Peter AU - Bennett P AD - Valentine Charlton Cat Centre, Sydney School of Veterinary Science, Faculty of Science, University of Sydney, NSW, Australia. LA - eng PT - Case Reports DEP - 20170504 PL - England TA - JFMS Open Rep JT - JFMS open reports JID - 101672978 PMC - PMC5423586 COIS- Conflict of interest: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. EDAT- 2017/05/12 06:00 MHDA- 2017/05/12 06:01 PMCR- 2017/05/04 CRDT- 2017/05/12 06:00 PHST- 2017/05/12 06:00 [entrez] PHST- 2017/05/12 06:00 [pubmed] PHST- 2017/05/12 06:01 [medline] PHST- 2017/05/04 00:00 [pmc-release] AID - 10.1177_2055116917706652 [pii] AID - 10.1177/2055116917706652 [doi] PST - epublish SO - JFMS Open Rep. 2017 May 4;3(1):2055116917706652. doi: 10.1177/2055116917706652. eCollection 2017 Jan-Jun.