PMID- 28491827
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 1016-1430 (Print)
IS  - 2251-6840 (Electronic)
IS  - 1016-1430 (Linking)
VI  - 30
DP  - 2016
TI  - Effect of exercise training on saliva brain derived neurotrophic factor, catalase 
      and vitamin c.
PG  - 452
AB  - Background: The balance between production of Reactive Oxygen Species (ROS) and 
      antioxidant defense in the body has important health implications. The aim of 
      this study was to investigate the changes in salivary antioxidants: catalase, 
      vitamin C and brain-derived neurotrophic factor (BDNF), in sedentary men at rest 
      and after acute exhaustive exercise. Methods: This randomized controlled clinical 
      trial (The registry code IRCT2011053212431N1) recruited twenty-five sedentary men 
      (age=21+/-3yrs; height=172+/-8cm; weight=66+/-9kg; VO2 max=37.6+/-7.4mL*kgkg(-1)*min(-1)) 
      participated in a double-blind randomized experiment. Unstimulated whole saliva 
      samples were collected before, immediately and 1 hour after exhaustive treadmill 
      running. Catalase, vitamin C (Vit C) concentration, and BDNF concentrations were 
      determined using biochemical assays and ELISA respectively. Repeated measures 
      ANOVA and Bonferroni posthoc test were used to analyze data. Results: The results 
      of the present study showed that an acute intensive exercise causes a reduction 
      in salivary catalase, Vit C and also BDNF concentration (p<0.05) compared with 
      pre-exercise. Both catalase and Vit C showed a tendency to return to pre-exercise 
      value after one hour. However, BDNF continued to reduction at least 1 hour after 
      the ending of the training. Conclusion: Reduction in antioxidants capacity of 
      saliva might reflects disturbance in natural antioxidant defense mechanisms of 
      the body after an acute intensive physical stress and possible further health 
      threatening consequences.
FAU - Babaei, Parvin
AU  - Babaei P
AD  - Neuroscience Research Center, Faculty of Medicine, Guilan University of Medical 
      Sciences, Rasht, Iran & Cellular & Molecular Research Center, Guilan University 
      of Medical Sciences, Rasht, Iran. p_babaei@gums.ac.ir.
FAU - Damirchi, Arsalan
AU  - Damirchi A
AD  - Professor of Sports Physiology, Faculty of Physical Education and Sports 
      Sciences, University of Guilan, Rasht, Iran. damirchi@guilan.ac.ir.
FAU - Soltani Tehrani, Bahram
AU  - Soltani Tehrani B
AD  - Associate Professor of Pharmacology, Cellular & Molecular Research Center, Guilan 
      University of Medical Sciences, Rasht, Iran. bahram_s_t@yahoo.com.
FAU - Nazari, Yazgaldi
AU  - Nazari Y
AD  - PhD student of Exercise Physiology, Faculty of Physical Education and Sports 
      Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran. y.nazari53@gmail.com.
FAU - Sariri, Reyhaneh
AU  - Sariri R
AD  - Professor of Biochemistry, Faculty of Science, University of Guilan, Rasht, Iran. 
      sariri@guilan.ac.ir.
FAU - Hoseini, Rastegar
AU  - Hoseini R
AD  - Department of Sport Science and Physical Education, Kermanshah Branch, Islamic 
      Azad University, Kermanshah, Iran. rastegar.hoseini@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20161212
PL  - Iran
TA  - Med J Islam Repub Iran
JT  - Medical journal of the Islamic Republic of Iran
JID - 8910777
PMC - PMC5419233
OTO - NOTNLM
OT  - Antioxidants
OT  - BDNF
OT  - Catalase
OT  - Exercise
OT  - Saliva
OT  - Vitamin C
EDAT- 2017/05/12 06:00
MHDA- 2017/05/12 06:01
PMCR- 2016/12/12
CRDT- 2017/05/12 06:00
PHST- 2015/02/12 00:00 [received]
PHST- 2016/08/15 00:00 [accepted]
PHST- 2017/05/12 06:00 [entrez]
PHST- 2017/05/12 06:00 [pubmed]
PHST- 2017/05/12 06:01 [medline]
PHST- 2016/12/12 00:00 [pmc-release]
PST - epublish
SO  - Med J Islam Repub Iran. 2016 Dec 12;30:452. eCollection 2016.