PMID- 28497919
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2092-7355 (Print)
IS  - 2092-7363 (Electronic)
IS  - 2092-7355 (Linking)
VI  - 9
IP  - 4
DP  - 2017 Jul
TI  - Accurate Determination of Childhood Food Allergy Prevalence and Correction of 
      Unnecessary Avoidance.
PG  - 322-328
LID - 10.4168/aair.2017.9.4.322 [doi]
AB  - PURPOSE: Because the true prevalence of food allergy (FA), as based on the 
      results of an oral food challenge test (OFC), is unknown, it is likely that 
      children with suspected FA unnecessarily eliminate potentially causative foods. 
      This study aimed to identify the prevalence of FA and to determine the proportion 
      of children who unnecessarily eliminate food. METHODS: To identify children with 
      FA, a primary survey was conducted via a questionnaire with all children aged 
      0-18 years in Niijima village (remote islands of Japan). In the secondary survey, 
      a detailed medical interview was conducted by doctors with children who currently 
      did not eat some foods. The third survey involved serum food-specific 
      immunoglobulin E (IgE) tests and an OFC for children with suspected FA. RESULTS: 
      Of 376 enrolled children, 374 (99.5%) completed the questionnaire. Some foods 
      were eliminated by 18.6% and 13.0% of all children and those >/=6 years old, 
      respectively. The target population for the secondary survey included 69 children 
      who all completed the medical interview. The target population for the third 
      survey consisted of 35 children, of whom 26 (74.3%) underwent the blood test. An 
      OFC was performed 35 times with 20 children. As a result, the prevalence of FA 
      was 4.9% in children of all ages and 4.7% in those >/=6 years old. Moreover, 55.0% 
      children were able to cease eliminating food intake. CONCLUSIONS: It is possible 
      that a considerable number of children unnecessarily eliminate food because of 
      suspected FA.
CI  - Copyright (c) 2017 The Korean Academy of Asthma, Allergy and Clinical Immunology . 
      The Korean Academy of Pediatric Allergy and Respiratory Disease
FAU - Okada, Yuki
AU  - Okada Y
AD  - Department of General Pediatrics, Tokyo Metropolitan Children's Medical Center, 
      Tokyo, Japan. y.okada0422@gmail.com.
AD  - Niijima Clinic, Tokyo, Japan.
AD  - Department of Pediatrics, Jichi Medical University, Tochigi, Japan.
FAU - Yamashita, Takumi
AU  - Yamashita T
AD  - Shikinejima Clinic, Tokyo, Japan.
AD  - Department of Pediatrics, Tokyo Metropolitan Bokutoh Hospital, Tokyo, Japan.
FAU - Kumagai, Hideki
AU  - Kumagai H
AD  - Department of Pediatrics, Jichi Medical University, Tochigi, Japan.
FAU - Morikawa, Yoshihiko
AU  - Morikawa Y
AD  - Clinical Research Support Center, Tokyo Metropolitan Children's Medical Center, 
      Tokyo, Japan.
FAU - Akasawa, Akira
AU  - Akasawa A
AD  - Department of Allergy, Tokyo Metropolitan Children's Medical Center, Tokyo, 
      Japan.
LA  - eng
PT  - Journal Article
PL  - Korea (South)
TA  - Allergy Asthma Immunol Res
JT  - Allergy, asthma & immunology research
JID - 101518382
PMC - PMC5446947
OTO - NOTNLM
OT  - Epidemiology
OT  - food allergy
OT  - oral food challenge test
COIS- There are no financial or other issues that might lead to conflict of interest.
EDAT- 2017/05/13 06:00
MHDA- 2017/05/13 06:01
PMCR- 2017/07/01
CRDT- 2017/05/13 06:00
PHST- 2016/07/05 00:00 [received]
PHST- 2016/12/06 00:00 [revised]
PHST- 2017/01/17 00:00 [accepted]
PHST- 2017/05/13 06:00 [entrez]
PHST- 2017/05/13 06:00 [pubmed]
PHST- 2017/05/13 06:01 [medline]
PHST- 2017/07/01 00:00 [pmc-release]
AID - 9.322 [pii]
AID - 10.4168/aair.2017.9.4.322 [doi]
PST - ppublish
SO  - Allergy Asthma Immunol Res. 2017 Jul;9(4):322-328. doi: 
      10.4168/aair.2017.9.4.322.