PMID- 28499569 OWN - NLM STAT- MEDLINE DCOM- 20170911 LR - 20180306 IS - 1532-8228 (Electronic) IS - 0883-9417 (Linking) VI - 31 IP - 3 DP - 2017 Jun TI - Prevalence of Major Depression and Its Associations With Demographic and Clinical Characteristics and Quality of Life in Chinese Patients With HBV-related Liver Diseases. PG - 287-290 LID - S0883-9417(16)30204-7 [pii] LID - 10.1016/j.apnu.2017.02.004 [doi] AB - BACKGROUND: There are no data about the frequency of major depression in patients with liver disease related to Hepatitis B virus (HBV) in China. This study examined the prevalence of major depression and its clinical correlates and association with quality of life (QOL) in patients with HBV-related liver diseases. METHOD: Altogether 634 patients with HBV-related liver diseases met study entry criteria and completed the survey. The diagnosis of major depression was established with the Mini International Neuropsychiatric Interview (MINI). Socio-demographic and clinical characteristics, Global Assessment of Functioning (GAF) and QOL were measured. RESULTS: The prevalence of major depression was 6.4%. Multivariable logistic regression analyses revealed that insomnia (P=0.01, OR=5.5, 95%CI=1.4-21.6) and global functioning (P<0.001, OR=0.6, 95% CI=0.5-0.7) were independently associated with major depression. Major depression was associated with both poor physical (F ((1, 634))=4.0, P=0.04) and mental QOL (F ((1, 634))=26.2, P<0.001). CONCLUSIONS: Given the negative impact of depression on patients' QOL, more attempts should be made to identify and treat it in HBV-related diseases. CI - Copyright (c) 2017. Published by Elsevier Inc. FAU - Liu, Mei AU - Liu M AD - Artificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, China. FAU - Li, Lu AU - Li L AD - Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China. FAU - Zheng, Su-Jun AU - Zheng SJ AD - Artificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, China. FAU - Zhao, Jing AU - Zhao J AD - Artificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, China. FAU - Ungvari, Gabor S AU - Ungvari GS AD - The University of Notre Dame Australia/Marian Centre, Perth, Australia; School of Psychiatry & Clinical Neurosciences, University of Western Australia, Perth, Australia. FAU - Hall, Brian J AU - Hall BJ AD - Global and Community Mental Health Research Group, Department of Psychology, University of Macau, Macao SAR, China; Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA. FAU - Duan, Zhong-Ping AU - Duan ZP AD - Artificial Liver Center, Beijing YouAn Hospital, Capital Medical University, Beijing, China. Electronic address: duan2517@163.com. FAU - Xiang, Yu-Tao AU - Xiang YT AD - Unit of Psychiatry, Faculty of Health Sciences, University of Macau, Macao SAR, China. Electronic address: xyutly@gmail.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20170206 PL - United States TA - Arch Psychiatr Nurs JT - Archives of psychiatric nursing JID - 8708534 SB - IM MH - Adult MH - China/epidemiology MH - Depressive Disorder, Major/*epidemiology MH - Female MH - *Hepatitis B virus MH - Humans MH - *Liver Diseases MH - Male MH - Middle Aged MH - Prevalence MH - Psychiatric Status Rating Scales/statistics & numerical data MH - *Quality of Life MH - Surveys and Questionnaires OTO - NOTNLM OT - China OT - Depression OT - HBV-related liver diseases OT - Quality of life EDAT- 2017/05/14 06:00 MHDA- 2017/09/12 06:00 CRDT- 2017/05/14 06:00 PHST- 2016/08/30 00:00 [received] PHST- 2017/01/11 00:00 [revised] PHST- 2017/02/04 00:00 [accepted] PHST- 2017/05/14 06:00 [entrez] PHST- 2017/05/14 06:00 [pubmed] PHST- 2017/09/12 06:00 [medline] AID - S0883-9417(16)30204-7 [pii] AID - 10.1016/j.apnu.2017.02.004 [doi] PST - ppublish SO - Arch Psychiatr Nurs. 2017 Jun;31(3):287-290. doi: 10.1016/j.apnu.2017.02.004. Epub 2017 Feb 6.