PMID- 28502143
OWN - NLM
STAT- MEDLINE
DCOM- 20171205
LR  - 20171205
IS  - 1110-4902 (Print)
VI  - 22
IP  - 2
DP  - 2015 Jun
TI  - Skin Prick Test Reactivity to Aeroallergens among Egyptian Patients with Isolated 
      Allergic Conjunctival Disease.
PG  - 41-47
AB  - Allergic conjunctival disease (ACD) is a type of ocular allergy, which includes 
      seasonal allergic conjunctivitis (SAC), perennial allergic conjunctivitis (PAC), 
      and vernal keratoconjunctivitis (VKC). Little is known about the pattern of 
      sensitization or prevalent aeroallergens among patients with isolated ACD in 
      Egypt We aimed to evaluate the prevalence of skin prick test positivity to common 
      aeroallergens among Egyptian patients with isolated allergic conjunctival 
      disease. The study included 75 patients with isolated ACD recruited from a 
      tertiary Egyptian outpatient clinic. Skin prick test (SPT) was performed for all 
      patients with common aeroallergens. Total serum immunoglobulin E (IgE) was 
      measured by ELISA. A positive SPT reaction was present among 32 patients (42.7%). 
      The most prevalent aeroallergens among all patients were mites and pollens (12% 
      respectively), followed by grass (8%) and hay dust (6.7%). Eight patients (10.7%) 
      had SAC, 19 patients (25.3%) had PAC, and 48 patients (64%) had VKC. Prevalence 
      of SPT positivity to indoor allergens was significantly more common among PAC 
      (52.6%) than among SAC (25%) and VKC (16.7%), P= 0.011. Outdoor allergen 
      sensitization did not differ significantly between the 3 subgroups, P= 0.614. 
      Elevated IgE levels were observed among 62.5%, 73.7% and 66.7% of patients with 
      SAC, PAC and VKC, respectively, with no statistically significant difference 
      between them, P= 0.806. In conclusion aeroallergen sensitization is common among 
      Egyptian patients with isolated ACD. Accordingly, SPT should be included in the 
      diagnostic workup of these patients.
CI  - Copyright(c) by the Egyptian Association of Immunologists.
FAU - Abo-Ali, Fawzeia H
AU  - Abo-Ali FH
AD  - Department of Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams 
      University, Cairo, Egypt.
FAU - Farres, Mohamed N
AU  - Farres MN
AD  - Department of Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams 
      University, Cairo, Egypt.
FAU - Shahin, Rasha Y
AU  - Shahin RY
AD  - Department of Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams 
      University, Cairo, Egypt.
FAU - Eissa, Abeer M
AU  - Eissa AM
AD  - Department of Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams 
      University, Cairo, Egypt.
FAU - Ahmed, Abutaleb
AU  - Ahmed A
AD  - Department of Allergy & Clinical Immunology, Faculty of Medicine, Ain Shams 
      University, Cairo, Egypt.
FAU - Abdel-Monsef, Ahmed
AU  - Abdel-Monsef A
AD  - Department of Ophthalmology, Faculty of Medicine, Ain Shams University, Cairo, 
      Egypt.
FAU - Arafa, Naglaa A
AU  - Arafa NA
AD  - Department of Community Environmental & Occupational Medicine, Faculty of 
      Medicine, Ain Shams University, Cairo, Egypt.
LA  - eng
PT  - Journal Article
PL  - Egypt
TA  - Egypt J Immunol
JT  - The Egyptian journal of immunology
JID - 9816016
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Allergens/*immunology
MH  - Conjunctival Diseases/*diagnosis/*immunology
MH  - Cross-Sectional Studies
MH  - Egypt
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/immunology
MH  - Male
MH  - Skin Tests/methods
EDAT- 2015/06/01 00:00
MHDA- 2015/06/01 00:01
CRDT- 2017/05/15 06:00
PHST- 2017/05/15 06:00 [entrez]
PHST- 2015/06/01 00:00 [pubmed]
PHST- 2015/06/01 00:01 [medline]
PST - ppublish
SO  - Egypt J Immunol. 2015 Jun;22(2):41-47.