PMID- 28503530 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 2288-176X (Print) IS - 2288-1778 (Electronic) IS - 2288-176X (Linking) VI - 13 IP - 2 DP - 2017 Apr TI - Caffeine supplementation affects the immunometabolic response to concurrent training. PG - 179-184 LID - 10.12965/jer.1734938.445 [doi] AB - The aim of the present study was to investigate the effects of caffeine (CAF) and carbohydrate (CHO) intake on strength performance and its metabolic and inflammatory responses during concurrent training. Seven active males ingested a double-placebo (P), CAF (capsule 5 mg/kg) or CHO (20% maltodextrin solution) supplementation before strength exercise. Participants performed three randomized sessions of 5,000-m high-intensity intermittent aerobic exercise at maximal intensity followed by strength exercise, performing after the P, CHO, and CAF intake. The blood samples were collected before (pre) and immediately after concurrent strength exercise (post). We found a similar number of repetitions and total volume in all supplementation groups. There was a main effect of time on glucose, lactate, and interleukin (IL)-6 (P<0.05). When compared the changes between groups (postvalues minus prevalues), there was lower glucose in CAF group when compared to CHO group (CAF= 5.0+/-10.4 vs. CHO=27.8+/-20 vs. P=15.1+/-14, P=0.031) and higher IL-6 levels (CAF=11.9+/-9.2 vs. CHO=-2.4+/-1.7 vs. P=4.3+/- 11.7, P=0.017). There was significant interaction for glucose and lactate (P<0.001). In conclusion, CAF and CHO intake did not improve strength performance during concurrent strength training in active males. However, CAF affected immunometabolic responses. FAU - Rossi, Fabricio Eduardo AU - Rossi FE AD - Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista, Presidente Prudente, Sao Paulo, Brazil. AD - Department of Sport, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil. FAU - Panissa, Valeria Leme Goncalves AU - Panissa VLG AD - Department of Sport, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil. FAU - Monteiro, Paula Aulves AU - Monteiro PA AD - Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista, Presidente Prudente, Sao Paulo, Brazil. FAU - Gerosa-Neto, Jose AU - Gerosa-Neto J AD - Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista, Presidente Prudente, Sao Paulo, Brazil. FAU - Caperuto, Erico Chagas AU - Caperuto EC AD - Human Movement Laboratory, Universidade Sao Judas Tadeu, Sao Paulo, Brazil. FAU - Cholewa, Jason Michael AU - Cholewa JM AD - Department of Kinesiology, Coastal Carolina University, Conway, SC, USA. FAU - Zagatto, Alessandro Moura AU - Zagatto AM AD - Department of Physical Education, Universidade Estadual Paulista, Bauru, Sao Paulo, Brazil. FAU - Lira, Fabio Santos AU - Lira FS AD - Exercise and Immunometabolism Research Group, Department of Physical Education, Universidade Estadual Paulista, Presidente Prudente, Sao Paulo, Brazil. LA - eng PT - Journal Article DEP - 20170430 PL - Korea (South) TA - J Exerc Rehabil JT - Journal of exercise rehabilitation JID - 101615171 PMC - PMC5412491 OTO - NOTNLM OT - Caffeine OT - Inflammation OT - Metabolism OT - Performance COIS- CONFLICT OF INTEREST No potential conflict of interest relevant to this article was reported. EDAT- 2017/05/16 06:00 MHDA- 2017/05/16 06:01 PMCR- 2017/04/30 CRDT- 2017/05/16 06:00 PHST- 2017/01/02 00:00 [received] PHST- 2017/04/03 00:00 [accepted] PHST- 2017/05/16 06:00 [entrez] PHST- 2017/05/16 06:00 [pubmed] PHST- 2017/05/16 06:01 [medline] PHST- 2017/04/30 00:00 [pmc-release] AID - jer-13-2-179 [pii] AID - 10.12965/jer.1734938.445 [doi] PST - epublish SO - J Exerc Rehabil. 2017 Apr 30;13(2):179-184. doi: 10.12965/jer.1734938.445. eCollection 2017 Apr.