PMID- 28511240 OWN - NLM STAT- MEDLINE DCOM- 20180905 LR - 20180905 IS - 1439-1058 (Electronic) IS - 0937-2032 (Linking) VI - 67 IP - 9-10 DP - 2017 Sep TI - [Treatment Outcome in Female In-Patients with Anorexia nervosa and Comorbid Personality Disorders Prevalence - Therapy Drop out and Weight Gain]. PG - 420-430 LID - 10.1055/s-0043-103271 [doi] AB - Introduction Personality disorders (PD) are among the most common comorbid disorders in female patients with Anorexia Nervosa (AN). Recent research findings suggest that comorbid PD are associated with a higher treatment drop-out rate and a worse therapeutic outcome. However, no study to date has distinguished between certain age groups concerning these issues. Research questions Therefore, the present study focuses on the prevalence of PD (1), treatment drop-out rates (2) and weight gain (3) in female in-patients with AN. Thereby, we differentiate among three age groups (17-24 years; 25-34 years; 35-65 years). Material & Methods We assessed female in-patients (N=331) with AN at the Helios Clinic in Bad Gronenbach in Germany using the Eating Disorders Inventory-2 and the psychotherapeutic-medical basic documentation at the beginning and at the end of their treatment. Furthermore, we investigated the drop-out rate and weight gain by comparing anorexic patients with and without comorbid PD that were diagnosed by clinicians using ICD-10 criteria. Results In sum, our patients with AN demonstrated a prevalence rate of 34% for one or more comorbid PD. Interestingly, patients between 17-24 years showed a lower prevalence rate of 22% compared to those between 25-34 years (42%) and 35-65 years (41%). Furthermore, younger age and comorbid PD seemed to be significant predictors for treatment dropout. One of the most striking results was that younger patients (17-24) without a comorbid PD had the highest weight gain during treatment. This could not be observed in patients with a comorbid PD, who demonstrated the highest weight gain between 25 and 34 years of age. Conclusion Our findings support the hypothesis that comorbid PD are related to a worse outcome in patients with eating disorders. Future studies might do well in assessing dimensional scores of personality disorders and other relevant aspects like for example the amount of social support to draw further conclusions on these associations. Our results emphasize the need for more disorder-specific interventions tailoring at patients with AN and comorbid PD to improve treatment outcome. CI - (c) Georg Thieme Verlag KG Stuttgart . New York. FAU - Link, Timo Maximilian AU - Link TM AD - Institut fur Psychologie, Universitat Innsbruck, Osterreich. FAU - Beermann, Ursula AU - Beermann U AD - Institut fur Psychologie, Universitat Innsbruck, Osterreich. FAU - Mestel, Robert AU - Mestel R AD - HELIOS Klinik in Bad Gronenbach, Berlin. FAU - Gander, Manuela AU - Gander M AD - Abteilung fur Kinder- und Jugendpsychiatrie, Medizinische Universitat Innsbruck, Osterreich. AD - Institut fur Psychologie, Universitat Innsbruck, Osterreich. LA - ger PT - Journal Article TT - Stationarer Therapieerfolg bei Patientinnen mit Anorexia Nervosa und komorbiden Personlichkeitsstorungen. DEP - 20170516 PL - Germany TA - Psychother Psychosom Med Psychol JT - Psychotherapie, Psychosomatik, medizinische Psychologie JID - 8002823 SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - Aged MH - Anorexia Nervosa/epidemiology/*psychology/*therapy MH - Female MH - Humans MH - Inpatients MH - Middle Aged MH - Patient Dropouts/psychology/statistics & numerical data MH - Personality Disorders/epidemiology/*psychology/*therapy MH - Prevalence MH - Treatment Outcome MH - Weight Gain MH - Young Adult COIS- Interessenkonflikt: Die Autoren geben an, dass kein Interessenkonflikt besteht. EDAT- 2017/05/17 06:00 MHDA- 2018/09/06 06:00 CRDT- 2017/05/17 06:00 PHST- 2017/05/17 06:00 [pubmed] PHST- 2018/09/06 06:00 [medline] PHST- 2017/05/17 06:00 [entrez] AID - 10.1055/s-0043-103271 [doi] PST - ppublish SO - Psychother Psychosom Med Psychol. 2017 Sep;67(9-10):420-430. doi: 10.1055/s-0043-103271. Epub 2017 May 16.