PMID- 28514581 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20191120 IS - 0890-9016 (Print) IS - 0890-9016 (Linking) VI - 31 DP - 2015 TI - Advancing Histocompatibility Testing for Solid Organ Transplantation - What is Needed? A Personal Opinion. PG - 193-201 AB - The field of histocompatibility testing has seen significant changes and advancements in the past quarter of a century. The introduction of polymerase chain reaction amplification into routine human leukocyte antigen (HLA) typing has informed us on the magnitude of polymorphism among HLA alleles. Solid phase testing for antibodies has provided unparalleled insight into antibody specificity and the role of antibody mediated rejection in transplant outcomes. Herein, we provide a brief overview of advancements in the field that are currently in progress. We also provide our own personal opinion on what is on the horizon and the direction in which we think the field should progress. CI - Copyright(c) 2016 by the Terasaki Foundation Laboratory. FAU - Cusick, Matthew F AU - Cusick MF AD - Transplant Immunology Laboratory, Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL. FAU - Tambur, Anat R AU - Tambur AR AD - Transplant Immunology Laboratory, Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL. LA - eng PT - Journal Article PL - United States TA - Clin Transpl JT - Clinical transplants JID - 8812419 OTO - NOTNLM OT - HLA OT - histocompatibility OT - transplantation EDAT- 2015/01/01 00:00 MHDA- 2015/01/01 00:01 CRDT- 2017/05/18 06:00 PHST- 2017/05/18 06:00 [entrez] PHST- 2015/01/01 00:00 [pubmed] PHST- 2015/01/01 00:01 [medline] PST - ppublish SO - Clin Transpl. 2015;31:193-201.