PMID- 28515956
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240326
IS  - 2055-0391 (Print)
IS  - 2055-0391 (Electronic)
IS  - 2055-0391 (Linking)
VI  - 59
DP  - 2017
TI  - Effects of phosalone consumption via feeding with or without sodium bentonite on 
      performance, blood metabolites and its transition to milk of Iranian Baluchi 
      sheep.
PG  - 10
LID - 10.1186/s40781-017-0135-7 [doi]
LID - 10
AB  - BACKGROUND: Transfer of pesticides from environment to animal products is 
      inevitable, so the purpose of the present work was to evaluate phosalone 
      consumption via feeding with or without sodium bentonite (SB) on performance, 
      blood metabolites and its transition to milk of Iranian Baluchi sheep. METHODS: 
      Twenty Baluchi ewes were divided into four treatments (P1 as control, P2, P3, and 
      P4) of five animals in which phosalone, an organophosphate pesticide, was given 
      via diet (only for P2 and P3) at a dose of 280 mg/sheep/day for 63 consecutive 
      days. The SB (32 g/sheep/day; for P3 and P4) was also evaluated for its ability 
      to reduce deleterious effects of phosalone in the sheep diets. The control group 
      (P1) did not receive any phosalone and SB during the experiment. Sampling was 
      conducted in two periods of time including weeks 5 and 9. RESULTS: Phosalone 
      residues were observed in the milk samples of P2 and P3 groups during two 
      sampling periods. During period 1, the transfer rate of phosalone from feed to 
      milk was 0.23 and 0.02%, respectively for the contaminated diets (P2 and P3), 
      which is relatively similar to period 2 (0.22 and 0.02%). Only 0.34 (period 1) 
      and 0.36% (period 2) of phosalone residue are excreted in the feces of P2 group 
      following its daily consumption. Transfer of phosalone from feed to milk was 
      affected (P < 0.05) by the dietary inclusion of a commercial SB, as it (SB) 
      decreased excretion of phosalone via milk (P3). The phosalone and SB alone or 
      together had no significant effect (P > 0.05) on the dry matter intake (DMI) and 
      body weight (BW) gain, but feed efficiency, milk production, milk fat, dry matter 
      (DM) and organic matter (OM) digestibility, acetylcholinesterase (AChE) 
      inhibitory activity, hemoglobin (Hb), red blood cell (RBC), serum glutamic 
      pyruvic transaminase (SGPT), serum glutamic oxaloacetic transaminase (SGOT), 
      albumin and mean corpuscular hemoglobin concentration (MCHC) affected by the 
      treatments in period 1 or 2 (P < 0.05). The Hb, RBC, and MCHC were significantly 
      decreased (P < 0.05) by about 9.72, 20.77, and 9.71%, respectively in the group 
      P2 as compared to those of the control group during period 1. The AChE inhibitory 
      activity (period 1 and 2) significantly increased when phosalone administered via 
      the diet (P < 0.05). CONCLUSIONS: Although there were no adverse effects on the 
      performance of sheep following the intake of phosalone alone (P2 vs. P1), but 
      other research on the long and short times to the phosalone in high and low doses 
      with more animals is suggested. Overall, compared to the control group, addition 
      of SB in the diet of sheep improved nutrient digestibility, animal performance, 
      and milk health.
FAU - Kazemi, Mohsen
AU  - Kazemi M
AD  - Department of Animal Science, Faculty of Agriculture and Animal Science, 
      University of Torbat-e Jam, Torbat-e Jam, Iran.
FAU - Torbaghan, Ameneh Eskandary
AU  - Torbaghan AE
AD  - Department of Environmental Health Engineering, Torbat-e Jam Faculty of Medical 
      Sciences, Torbat-e Jam, Iran.
FAU - Tahmasbi, Abdoul Mansour
AU  - Tahmasbi AM
AD  - Department of Animal Science, Faculty of Agriculture, Ferdowsi University of 
      Mashhad, Mashhad, Iran. ISNI: 0000 0001 0666 1211. GRID: grid.411301.6
FAU - Valizadeh, Reza
AU  - Valizadeh R
AD  - Department of Animal Science, Faculty of Agriculture, Ferdowsi University of 
      Mashhad, Mashhad, Iran. ISNI: 0000 0001 0666 1211. GRID: grid.411301.6
FAU - Naserian, Abbas Ali
AU  - Naserian AA
AD  - Department of Animal Science, Faculty of Agriculture, Ferdowsi University of 
      Mashhad, Mashhad, Iran. ISNI: 0000 0001 0666 1211. GRID: grid.411301.6
LA  - eng
PT  - Journal Article
DEP - 20170515
PL  - Korea (South)
TA  - J Anim Sci Technol
JT  - Journal of animal science and technology
JID - 101661694
PMC - PMC5430607
OTO - NOTNLM
OT  - Iranian Baluchi sheep
OT  - Milk
OT  - Performance
OT  - Phosalone
OT  - Sodium bentonite
EDAT- 2017/05/19 06:00
MHDA- 2017/05/19 06:01
PMCR- 2017/05/15
CRDT- 2017/05/19 06:00
PHST- 2017/01/03 00:00 [received]
PHST- 2017/04/21 00:00 [accepted]
PHST- 2017/05/19 06:00 [entrez]
PHST- 2017/05/19 06:00 [pubmed]
PHST- 2017/05/19 06:01 [medline]
PHST- 2017/05/15 00:00 [pmc-release]
AID - 135 [pii]
AID - 10.1186/s40781-017-0135-7 [doi]
PST - epublish
SO  - J Anim Sci Technol. 2017 May 15;59:10. doi: 10.1186/s40781-017-0135-7. 
      eCollection 2017.