PMID- 28524542 OWN - NLM STAT- MEDLINE DCOM- 20190621 LR - 20190621 IS - 1751-7893 (Electronic) IS - 1751-7885 (Linking) VI - 12 IP - 6 DP - 2018 Dec TI - Negative schemata about the self and others and paranoid ideation in at-risk states and those with persisting positive symptoms. PG - 1157-1165 LID - 10.1111/eip.12433 [doi] AB - BACKGROUND: The objective of this study is to test the conflicting theories concerning the association of negative self and other schemata and paranoid ideation. METHODS: A risk-based approach, including risk stratification, is used to gain insight into the association of the negative self and other schemata that may be shared by individuals or differentiate between individuals at clinical high risk (CHR) for a first-episode psychosis and those with full-blown psychosis. The dataset includes a sample of individuals at CHR (n = 137) and a sample of individuals with persisting positive symptoms (PPS, n = 211). The CHR sample was subdivided according to a prognostic index yielding 4 CHR sub-classes with increasing risk for transition to psychosis. RESULTS: Negative beliefs about the self were associated with paranoid ideation in CHR and a lower risk state. In the highest risk state and full-blown psychosis, there is an association with negative beliefs about others. CONCLUSION: These findings are in line with theories suggesting a switch from a predominantly activated negative self-schema to a malevolent others-schema in association with paranoid ideation along the risk-continuum. However, due to methodological limitations these results should be replicated by future studies. CI - (c) 2017 John Wiley & Sons Australia, Ltd. FAU - Muller, Hendrik AU - Muller H AD - Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany. FAU - de Millas, Walter AU - de Millas W AD - Department of Psychiatry and Psychotherapy, Charite University Medicine Campus Mitte, Berlin, Germany. FAU - Gaebel, Wolfgang AU - Gaebel W AD - Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany. FAU - Herrlich, Jutta AU - Herrlich J AD - Department of Psychiatry, Psychosomatics and Psychotherapy, Goethe-University of Frankfurt am Main, Frankfurt am Main, Germany. FAU - Hasan, Alkomiet AU - Hasan A AD - Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, Munich, Germany. FAU - Janssen, Birgit AU - Janssen B AD - Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany. FAU - Juckel, Georg AU - Juckel G AD - Department of Psychiatry, Psychotherapy, and Preventive Medicine, Ruhr University Bochum, Bochum, Germany. FAU - Karow, Anne AU - Karow A AD - Psychosis Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany. FAU - Kircher, Tilo AU - Kircher T AD - Department of Psychiatry and Psychotherapy, Philipps-University of Marburg, Marburg, Germany. FAU - Kiszkenow-Baker, Stefanie AU - Kiszkenow-Baker S AD - Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany. FAU - Klingberg, Stefan AU - Klingberg S AD - Department of Psychiatry and Psychotherapy, Eberhard-Karls-University of Tuebingen, Tuebingen, Germany. FAU - Klosterkotter, Joachim AU - Klosterkotter J AD - Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany. FAU - Kruger-Ozgurdal, Seza AU - Kruger-Ozgurdal S AD - Department of Psychiatry, Psychotherapy, and Preventive Medicine, Ruhr University Bochum, Bochum, Germany. FAU - Lambert, Martin AU - Lambert M AD - Psychosis Centre, Department of Psychiatry and Psychotherapy, Centre for Psychosocial Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany. FAU - Lautenschlager, Marion AU - Lautenschlager M AD - Department of Psychiatry and Psychotherapy, Charite University Medicine Campus Mitte, Berlin, Germany. FAU - Maier, Wolfgang AU - Maier W AD - Department of Psychiatry and Psychotherapy, Rhineland Friedrich Wilhelms University of Bonn, Bonn, Germany. FAU - Michel, Tanja Maria AU - Michel TM AD - Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen, Aachen, Germany. FAU - Mehl, Stefanie AU - Mehl S AD - Department of Psychiatry and Psychotherapy, Philipps-University of Marburg, Marburg, Germany. FAU - Muller, Bernhard W AU - Muller BW AD - Department for Psychiatry and Psychotherapy, LVR-Clinic Essen, Faculty of Medicine, University of Duisburg-Essen, Duisburg, Germany. FAU - Putzfeld, Verena AU - Putzfeld V AD - Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany. FAU - Rausch, Franziska AU - Rausch F AD - Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany. FAU - Riedel, Michael AU - Riedel M AD - Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich, Munich, Germany. FAU - Sartory, Gudrun AU - Sartory G AD - Department of Clinical Psychology, University of Wuppertal, Wuppertal, Germany. FAU - Schneider, Frank AU - Schneider F AD - Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen, Aachen, Germany. FAU - Wagner, Michael AU - Wagner M AD - Department of Psychiatry and Psychotherapy, Rhineland Friedrich Wilhelms University of Bonn, Bonn, Germany. FAU - Wiedemann, Georg AU - Wiedemann G AD - Department of Psychiatry, Psychosomatics and Psychotherapy, Goethe-University of Frankfurt am Main, Frankfurt am Main, Germany. FAU - Wittorf, Andreas AU - Wittorf A AD - Department of Psychiatry and Psychotherapy, Eberhard-Karls-University of Tuebingen, Tuebingen, Germany. FAU - Wobrock, Thomas AU - Wobrock T AD - Department of Psychiatry and Psychotherapy, Georg-August-University Goettingen, Goettingen, Germany. FAU - Wolwer, Wolfgang AU - Wolwer W AD - Department of Psychiatry and Psychotherapy, Medical Faculty, Heinrich-Heine-University, Duesseldorf, Germany. FAU - Zink, Mathias AU - Zink M AD - Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany. FAU - Bechdolf, Andreas AU - Bechdolf A AD - Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany. AD - Department of Psychiatry, Psychotherapy and Psychosomatics, Vivantes Clinic am Urban and Vivantes Clinic im Friedrichshain, Academic Hospital Charite, Berlin, Germany. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20170519 PL - Australia TA - Early Interv Psychiatry JT - Early intervention in psychiatry JID - 101320027 SB - IM MH - Adult MH - *Culture MH - Female MH - Humans MH - Male MH - Paranoid Disorders/complications/*diagnosis MH - Prodromal Symptoms MH - Prognosis MH - Psychotic Disorders/complications/*diagnosis MH - Young Adult OTO - NOTNLM OT - paranoia OT - prodrome OT - psychosis OT - schemata OT - suspiciousness EDAT- 2017/05/20 06:00 MHDA- 2019/06/22 06:00 CRDT- 2017/05/20 06:00 PHST- 2016/07/12 00:00 [received] PHST- 2016/12/13 00:00 [revised] PHST- 2017/01/19 00:00 [accepted] PHST- 2017/05/20 06:00 [pubmed] PHST- 2019/06/22 06:00 [medline] PHST- 2017/05/20 06:00 [entrez] AID - 10.1111/eip.12433 [doi] PST - ppublish SO - Early Interv Psychiatry. 2018 Dec;12(6):1157-1165. doi: 10.1111/eip.12433. Epub 2017 May 19.