PMID- 28527920
OWN - NLM
STAT- MEDLINE
DCOM- 20180607
LR  - 20220321
IS  - 1879-016X (Electronic)
IS  - 0163-7258 (Linking)
VI  - 179
DP  - 2017 Nov
TI  - Emerging bronchoscopic treatments for chronic obstructive pulmonary disease.
PG  - 96-101
LID - S0163-7258(17)30126-2 [pii]
LID - 10.1016/j.pharmthera.2017.05.007 [doi]
AB  - Chronic obstructive pulmonary disease (COPD) is a progressive lung disease 
      characterized by pathophysiological factors including airflow limitation, 
      hyperinflation and reduced gas exchange. Treatment consists of lifestyle changes, 
      lung rehabilitation and pharmacological therapies such as long acting 
      beta-2-agonists (LABA) and long acting muscarinic antagonists (LAMA). More 
      recently bronchoscopic treatments are emerging for COPD. Among them endobronchial 
      valves (EBV) and endobronchial coils (EBC), next to endobronchial stents, 
      sclerosing agents, targeted lung denervation and liquid nitrogen metered 
      cryospray. In this review we aim to summarize the new emerging bronchoscopic 
      treatments and their effect sizes compared with lung rehabilitation and 
      pharmacological therapies.
CI  - Copyright (c) 2017 The Author(s). Published by Elsevier Inc. All rights reserved.
FAU - van Geffen, Wouter H
AU  - van Geffen WH
AD  - Medical Centre Leeuwarden, Department of Respiratory Medicine, Leeuwarden, The 
      Netherlands; University of Groningen, University Medical Center Groningen, 
      Department of Pulmonary Diseases, Groningen, The Netherlands. Electronic address: 
      wouter.van.geffen@znb.nl.
FAU - Kerstjens, Huib A M
AU  - Kerstjens HAM
AD  - University of Groningen, University Medical Center Groningen, Department of 
      Pulmonary Diseases, Groningen, The Netherlands.
FAU - Slebos, Dirk-Jan
AU  - Slebos DJ
AD  - University of Groningen, University Medical Center Groningen, Department of 
      Pulmonary Diseases, Groningen, The Netherlands.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170518
PL  - England
TA  - Pharmacol Ther
JT  - Pharmacology & therapeutics
JID - 7905840
SB  - IM
MH  - *Bronchoscopy
MH  - Humans
MH  - Lung/physiopathology
MH  - Pneumonectomy
MH  - Pulmonary Disease, Chronic Obstructive/drug therapy/physiopathology/*surgery
OTO - NOTNLM
OT  - Bronchoscopic treatment
OT  - Chronic obstructive pulmonary disease (COPD)
OT  - Endobronchial coils (EBC)
OT  - Endobronchial valves (EBV)
OT  - Hyperinflation
OT  - Lung volume reduction
EDAT- 2017/05/22 06:00
MHDA- 2018/06/08 06:00
CRDT- 2017/05/22 06:00
PHST- 2017/05/22 06:00 [pubmed]
PHST- 2018/06/08 06:00 [medline]
PHST- 2017/05/22 06:00 [entrez]
AID - S0163-7258(17)30126-2 [pii]
AID - 10.1016/j.pharmthera.2017.05.007 [doi]
PST - ppublish
SO  - Pharmacol Ther. 2017 Nov;179:96-101. doi: 10.1016/j.pharmthera.2017.05.007. Epub 
      2017 May 18.