PMID- 28529723
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20191120
IS  - 2046-1402 (Print)
IS  - 2046-1402 (Electronic)
IS  - 2046-1402 (Linking)
VI  - 6
DP  - 2017
TI  - Role of major histocompatibility complex variation in graft-versus-host disease 
      after hematopoietic cell transplantation.
PG  - 617
LID - 10.12688/f1000research.10990.1 [doi]
LID - 617
AB  - Graft-versus-host disease (GVHD) remains a significant potentially 
      life-threatening complication of allogeneic hematopoietic cell transplantation 
      (HCT). Since the discovery of the human leukocyte antigen (HLA) system over 50 
      years ago, significant advances have clarified the nature of HLA variation 
      between transplant recipients and donors as a chief etiology of GVHD. New 
      information on coding and non-coding gene variation and GVHD risk provides 
      clinicians with options to consider selected mismatched donors when matched 
      donors are not available. These advances have increased the availability of 
      unrelated donors for patients in need of a transplant and have lowered the 
      overall morbidity and mortality of HCT.
FAU - Petersdorf, Effie W
AU  - Petersdorf EW
AD  - Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
LA  - eng
GR  - U01 AI069197/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Review
DEP - 20170503
PL  - England
TA  - F1000Res
JT  - F1000Research
JID - 101594320
PMC - PMC5419254
OTO - NOTNLM
OT  - HLA expression
OT  - MHC
OT  - haplotype
OT  - hematopoietic cell transplantation
OT  - permissible HLA mismatch
COIS- Competing interests: The author declares that she has no competing interests.No 
      competing interests were disclosed.No competing interests were disclosed.
EDAT- 2017/05/23 06:00
MHDA- 2017/05/23 06:01
PMCR- 2017/05/03
CRDT- 2017/05/23 06:00
PHST- 2017/04/25 00:00 [accepted]
PHST- 2017/05/23 06:00 [entrez]
PHST- 2017/05/23 06:00 [pubmed]
PHST- 2017/05/23 06:01 [medline]
PHST- 2017/05/03 00:00 [pmc-release]
AID - 10.12688/f1000research.10990.1 [doi]
PST - epublish
SO  - F1000Res. 2017 May 3;6:617. doi: 10.12688/f1000research.10990.1. eCollection 
      2017.