PMID- 28539208 OWN - NLM STAT- MEDLINE DCOM- 20180503 LR - 20180503 IS - 1874-1754 (Electronic) IS - 0167-5273 (Linking) VI - 243 DP - 2017 Sep 15 TI - Birth weight, length and head circumference: Progression and impact over the outcome of patients with congenital heart disease. PG - 194-196 LID - S0167-5273(17)30305-4 [pii] LID - 10.1016/j.ijcard.2017.05.078 [doi] AB - BACKGROUND: There are few studies assessing the birth measures of patients with congenital heart disease (CHD). Our aim to evaluate their progression and impact over the outcome. METHODS: The cases consisted of patients with CHD during their first hospitalization in a reference cardiac and pediatric intensive care unit (ICU) from Southern Brazil. Controls were composed of patients with no clinical evidence of CHD hospitalized soon after cases. The cases underwent high-resolution karyotype and fluorescence in situ hybridization (FISH) for 22q11 microdeletion. We analyzed birth weight, length and head circumference of patients of both groups. For CHD patients, we evaluated their progression and impact until hospitalization at ICU. RESULTS: Our sample was composed of 198 cases and controls. We observe a difference in birth weight of CHD patients only in relation to general population. There was a significant increase in children with CHD and weight below the lower limit from birth until the hospitalization at ICU, and this occurred more in those without complex CHD. Syndromic patients and with an extracardiac malformation also presented a greater difficulty to maintain not only the weight but also the length/height until the hospitalization. Individuals with weight below the lower limit at hospitalization who died had a tendency to present longer stay at ICU. CONCLUSIONS: Some CHD patients, especially without complex defects, and with syndromic aspect and a major extracardiac malformation, present a higher difficult to maintain their weight and growth, and, therefore, may be at risk and should be more closely monitored. CI - Copyright (c) 2017 Elsevier B.V. All rights reserved. FAU - Silveira, Danielle Bernardi AU - Silveira DB AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - da Rosa, Ernani Bohrer AU - da Rosa EB AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - Correia, Jamile Dutra AU - Correia JD AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - Trevisan, Patricia AU - Trevisan P AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - Fiegenbaum, Marilu AU - Fiegenbaum M AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil; Human Genetics, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil; Graduate Program in Biosciences, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - Oliveira, Ceres Andreia AU - Oliveira CA AD - Institute of Education and Research, Hospital Moinhos de Vento, RS, Brazil. FAU - Grapiglia, Carolina Geitens AU - Grapiglia CG AD - Graduation in Nursing, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - Nunes, Mauricio Rouvel AU - Nunes MR AD - Graduation in Nursing, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - Rosa, Rosana Cardoso Manique AU - Rosa RCM AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil. FAU - Zen, Tatiana Diehl AU - Zen TD AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil; Pharmacy, Faculdade de Ciencias da Saude, Centro Universitario Ritter dos Reis - UniRitter, Porto Alegre, RS, Brazil. FAU - Zen, Paulo Ricardo Gazzola AU - Zen PRG AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil; Graduate Program in Biosciences, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil; Clinical Genetics, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA) and Complexo Hospitalar Santa Casa de Porto Alegre (CHSCPA), RS, Brazil. FAU - Rosa, Rafael Fabiano Machado AU - Rosa RFM AD - Graduate Program in Pathology, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil; Graduate Program in Biosciences, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA), RS, Brazil; Clinical Genetics, Universidade Federal de Ciencias da Saude de Porto Alegre (UFCSPA) and Complexo Hospitalar Santa Casa de Porto Alegre (CHSCPA), RS, Brazil. Electronic address: rfmrosa@gmail.com. LA - eng PT - Journal Article DEP - 20170518 PL - Netherlands TA - Int J Cardiol JT - International journal of cardiology JID - 8200291 SB - IM MH - Birth Weight/*physiology MH - Body Height/*physiology MH - Brazil/epidemiology MH - *Disease Progression MH - Female MH - Head/*growth & development MH - Heart Defects, Congenital/diagnosis/mortality/*physiopathology MH - Hospitalization/trends MH - Humans MH - Infant MH - Infant, Newborn MH - Male MH - Prospective Studies MH - Treatment Outcome OTO - NOTNLM OT - Birth OT - Congenital heart defects OT - Length OT - Physical exam OT - Syndromic aspect OT - Weight EDAT- 2017/05/26 06:00 MHDA- 2018/05/04 06:00 CRDT- 2017/05/26 06:00 PHST- 2017/01/16 00:00 [received] PHST- 2017/05/17 00:00 [accepted] PHST- 2017/05/26 06:00 [pubmed] PHST- 2018/05/04 06:00 [medline] PHST- 2017/05/26 06:00 [entrez] AID - S0167-5273(17)30305-4 [pii] AID - 10.1016/j.ijcard.2017.05.078 [doi] PST - ppublish SO - Int J Cardiol. 2017 Sep 15;243:194-196. doi: 10.1016/j.ijcard.2017.05.078. Epub 2017 May 18.